ChemicalBook >> CAS DataBase List >>(R)-3-Hydroxypyrrolidine
(R)-3-Hydroxypyrrolidine
- CAS No.
- 2799-21-5
- Chemical Name:
- (R)-3-Hydroxypyrrolidine
- Synonyms
- (R)-PYRROLIDIN-3-OL;(3R)-Pyrrolidin-3-ol;R-HP;98%，ee99%;(R)-3-PYRROLIDINOL;(-)-3-Pyrrolidinol;(3R)-3-PYRROLIDINOL;3-PYRROLIDINOL, (R);(R)-Pyrrolidine-3-ol;R-(-)-3-PYRROLIDINOL
- CBNumber:
- CB7494161
- Molecular Formula:
- C4H9NO
- Molecular Weight:
- 87.12
- MDL Number:
- MFCD00145220
- MOL File:
- 2799-21-5.mol
- MSDS File:
- SDS
Last updated:2024-04-08 13:48:25
| Melting point | 15°C |
|---|---|
| Boiling point | 215-216 °C (lit.) |
| alpha | 6.5 º (c=3.5% in MeOH) |
| Density | 1.078 g/mL at 20 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 14.91±0.20(Predicted) |
| form | Viscous Liquid |
| color | Clear yellow to orange-brown |
| Specific Gravity | 1.048 |
| optical activity | [α]20/D +6.5°, c = 3.5 in methanol |
| Water Solubility | Soluble in water and methanol. |
| Sensitive | Air Sensitive & Hygroscopic |
| BRN | 5376132 |
| CAS DataBase Reference | 2799-21-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280a-P321-P332+P313-P337+P313-P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-34 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
(R)-3-Hydroxypyrrolidine price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 382981 | (R)-3-Pyrrolidinol 98% | 2799-21-5 | 1g | $85.4 | 2023-01-07 | Buy |
| Sigma-Aldrich | 382981 | (R)-3-Pyrrolidinol 98% | 2799-21-5 | 5g | $137 | 2023-01-07 | Buy |
| TCI Chemical | P1608 | (R)-3-Pyrrolidinol >98.0%(GC) | 2799-21-5 | 1g | $50 | 2024-03-01 | Buy |
| TCI Chemical | P1608 | (R)-3-Pyrrolidinol >98.0%(GC) | 2799-21-5 | 5g | $151 | 2024-03-01 | Buy |
| Alfa Aesar | L19499 | (R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99% | 2799-21-5 | 1g | $61.65 | 2024-03-01 | Buy |
(R)-3-Hydroxypyrrolidine Chemical Properties,Uses,Production
Chemical Properties
clear yellow to orange-brown viscous liquid
Uses
(R)-Pyrrolidin-3-ol is used in preparation of allosteric BCR-ABL bifunctional proteolysis targeting chimera compounds.
Purification Methods
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]
(R)-3-Hydroxypyrrolidine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Global( 304)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2169 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
View Lastest Price from (R)-3-Hydroxypyrrolidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-08 | (R)-3-Hydroxypyrrolidine
2799-21-5
|
US $34.00-1.20 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2024-01-02 | (R)-3-Hydroxypyrrolidine
2799-21-5
|
US $80.00-800.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2023-09-06 | (R)-3-Hydroxypyrrolidine
2799-21-5
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- (R)-3-Hydroxypyrrolidine
2799-21-5
- US $34.00-1.20 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- (R)-3-Hydroxypyrrolidine
2799-21-5
- US $80.00-800.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- (R)-3-Hydroxypyrrolidine
2799-21-5
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
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(R)-3-Pyrrolidinol>
(R)-3-Hydroxypyrrolidine USP/EP/BP
(3R)-Pyrrolidin-3-ol
(R)-PYRROLIDIN-3-OL
(-)-3-Pyrrolidinol
2799-21-5
Asymmetric Synthesis
Simple Alcohols (Chiral)
Chiral Building Blocks
Heterocyclic Building Blocks
Pyrrolidines
pharmacetical
API intermediates
Chiral Building Blocks
Simple Alcohols (Chiral)
Synthetic Organic Chemistry