Identification | More | [Name]
8-Aminooctanoic acid | [CAS]
1002-57-9 | [Synonyms]
8-AMINOCAPRYLIC ACID 8-AMINOOCTANOIC ACID GAMMA-AMINOCAPRYLIC ACID H-8-AMINOCAPRYLIC ACID H-8-AMINOOCTANOIC ACID H-AOC(8)-OH NH2-(CH2)7-COOH OMEGA-AMINOCAPRYLIC ACID RARECHEM EM WB 0024 TIMTEC-BB SBB006735 Octanoic acid, 8-amino- w-Aminocaprylic acid OMEGA-AMINOCAPRYLIC ACID CRYSTALLINE omega-Aminocaprylic acid, 99+% i-aminocaprylic acid 8-amino capylic acid 8-AMINOOCTANOIC ACID PURUM 98% | [EINECS(EC#)]
213-687-9 | [Molecular Formula]
C8H17NO2 | [MDL Number]
MFCD00008245 | [Molecular Weight]
159.23 | [MOL File]
1002-57-9.mol |
Chemical Properties | Back Directory | [Appearance]
WHITE TO SLIGHTLY BEIGE CRYSTALLINE POWDER | [Melting point ]
194 °C (dec.) (lit.) | [Boiling point ]
286.0±23.0 °C(Predicted) | [density ]
1.0500 (estimate) | [refractive index ]
1.4630 (estimate) | [storage temp. ]
Store at 0-5°C | [solubility ]
Methanol (Very Slightly), Water (Slightly) | [form ]
Crystalline Powder | [pka]
4.76±0.10(Predicted) | [color ]
White to slightly beige | [Water Solubility ]
Soluble in water. | [BRN ]
1756493 | [InChI]
InChI=1S/C8H17NO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7,9H2,(H,10,11) | [InChIKey]
UQXNEWQGGVUVQA-UHFFFAOYSA-N | [SMILES]
C(O)(=O)CCCCCCCN | [CAS DataBase Reference]
1002-57-9(CAS DataBase Reference) | [NIST Chemistry Reference]
8-Aminocaprylic acid(1002-57-9) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . S37/39:Wear suitable gloves and eye/face protection . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29224985 |
Hazard Information | Back Directory | [Chemical Properties]
WHITE TO SLIGHTLY BEIGE CRYSTALLINE POWDER | [Uses]
8-Aminooctanoic acid is involved in the preparation of lactams using enzyme catalyzed aminolysis. | [Definition]
ChEBI: 8-aminooctanoic acid is an omega-amino fatty acid that is octanoic acid which carries an amino group at position 8. It has a role as a human metabolite. It is a medium-chain fatty acid and an omega-amino fatty acid. | [Synthesis]
In a 1 l flask with paddle stirrer, internal thermometer and reflux condenser, 142.6 g (1 mol) of 2-azacyclononanone and 110 g (1 mol) of about 36 wt.-% sodium hydroxide solution are boiled under reflux for 4 hours. The solution is subsequently cooled to about 80 °C and mixed with Lewatit SP-112?. After one hour, the acidic ion exchanger is filtered. 500 g of 2-Propanol is added dropwise to the mixture at 80 °C, and the homogeneous solution is slowly cooled to -5 °C. The precipitated solid is filtered and washed with 50 g of 2-propanol. After drying at 85 °C and 20 mbar, 8-Aminooctanoic acid is obtained as a fine colorless powder. A colorless powder. Yield: 127 g (80%). Melting point: 191-193 °C (Lit.: 194 °C).
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