ChemicalBook--->CAS DataBase List--->126631-93-4

126631-93-4

126631-93-4 Structure

126631-93-4 Structure
IdentificationMore
[Name]

N-Fmoc-8-Aminooctanoic acid
[CAS]

126631-93-4
[Synonyms]

8-(FMOC-AMINO)CAPRYLIC ACID
8-(FMOC-AMINO)OCTANOIC ACID
FMOC-8-AMINOCAPRYLIC ACID
FMOC-8-AMINOOCTANOIC ACID
FMOC-8-AOC-OH
FMOC-AMINOCAPRYLIC ACID
FMOC-AOC(8)-OH
FMOC-NH-(CH2)7-COOH
N-(9-FLUORENYLMETHOXYCARBONYL)-8-AMINOCAPRYLIC ACID
N-(9-FLUORENYLMETHOXYCARBONYL)-8-AMINOOCTANOIC ACID
N-(9-FLUORENYLMETHYLOXYCARBONYL)-8-AMINO-OCTANOIC ACID
N-ALPHA-FMOC-8-AMINOOCTANOIC ACID
N-FMOC-8-AMINOOCTANOIC ACID
RARECHEM EM WB 0026
NALPHA-9-Fluorenylmethoxycarbonyl-8-aminooctanoic acid
Fmoc-omega-aminocaprylic acid
Fmoc-8-aminooctanoic acid (Fmoc-aminocaprylic acid)
8-Aminooctanoic acid, N-FMOC protected
8-(Fmoc-amino)caprylic acid, 8-(Fmoc-amino)octanoic acid
8-(9H-Fluoren-9-ylmethoxycarbonylamino)octanoic acid
[Molecular Formula]

C23H27NO4
[MDL Number]

MFCD00235890
[Molecular Weight]

381.46
[MOL File]

126631-93-4.mol
Chemical PropertiesBack Directory
[Melting point ]

118-119 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
[Boiling point ]

597.7±33.0 °C(Predicted)
[density ]

1.174±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[form ]

Powder
[pka]

4.77±0.10(Predicted)
[color ]

White
[BRN ]

8286497
[CAS DataBase Reference]

126631-93-4(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[HazardClass ]

IRRITANT
[HS Code ]

29242990
Hazard InformationBack Directory
[Description]

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
[Chemical Properties]

White powder
[Uses]

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

N-Fmoc-8-Aminooctanoic acid(126631-93-4)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

126631-93-4(sigmaaldrich)
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