| Identification | Back Directory | [Name]
2-Chloromethoxyethylchloride | [CAS]
1462-33-5 | [Synonyms]
chloroethylchloromethylether
2-CHLOROMETHOXYETHYLCHLORIDE
1-CHLORO-2-CHLOROMETHOXYETHANE
2-CHLOROETHYLCHLOROMETHYLESTER
(2-Chloroethoxy)methyl Chloride
2-CHLOROETHYL CHLOROMETHYL ETHER
Ethane, 1-chloro-2-(chloromethoxy)-
2-Chloroethyl Chloromethyl Ether >
2-CHLOROETHYL CHLOROMETHYL ETHER 96+% | [Molecular Formula]
C3H6Cl2O | [MDL Number]
MFCD00191406 | [MOL File]
1462-33-5.mol | [Molecular Weight]
128.99 |
| Chemical Properties | Back Directory | [Boiling point ]
147 °C | [density ]
1,28 g/cm3 | [refractive index ]
1.4570-1.4600 | [storage temp. ]
0-10°C | [solubility ]
Chloroform | [form ]
Oil | [color ]
Yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Oil | [Uses]
(2-Chloroethoxy)methyl Chloride (cas# 1462-33-5) is a compound useful in organic synthesis. | [Synthesis]
The most conveniently prepared of 2-Chloromethoxyethylchloride is by reaction of 2-chloroethanol and 1,3,5-trioxane with HCl(g) at 0 °C (1.0 mol scale, 66% yield).
| [Precautions]
2-Chloromethoxyethylchloride is a deviate of Chloromethyl ethers, which are recognized carcinogens. The reagent should be prepared and handled in an efficient fume hood, and skin contact should be avoided. Chloromethyl ethers are also moisture-sensitive and should be stored and transferred under an inert atmosphere. Excess reagent should be hydrolyzed in water before removing it from the fume hood.
| [References]
1. Ogle, C. A.; Wilson, T. E.; Stowe, J. A. S 1990, 495.
2. Hutchison, A. J.; Kishi, Y. JACS 1979, 101, 6786.
3. Farren, J. W.; Fife, H. F.; Clark, F. E.; Garland, C. E. JACS 1925, 47, 2419.
4. For similar procedures, see ref 5 and Holy, A.; Rosenberg, I.; Dvorakova, H. CCC 1989, 54, 2190 (4.6 mol scale, 74% yield) |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Aemon Chemical
|
| Telephone: |
0086-755-86198205 |
| Website: |
www.aemonchem.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
DoCheman Shanghai Co., Ltd.
|
| Telephone: |
+86-21-31664694 157 21077413 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList16824/0_EN.htm |
|