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627-11-2

627-11-2 Structure

627-11-2 Structure
IdentificationMore
[Name]

2-Chloroethyl chloroformate
[CAS]

627-11-2
[Synonyms]

2-CHLOROETHOXYCARBONYL CHLORIDE
2-CHLOROETHYL CHLOROFORMATE
BETA-CHLORO ETHYL CHLOROFORMATE
CHLORO ETHYL CHLOROFORMATE
CHLOROFORMIC ACID 2-CHLOROETHYL ESTER
2-Chlorethylester kyseliny chlormravenci
2-chlorethylesterkyselinychlormravenci
2-chlorethylesterkyselinychlormravenci(czech)
2-Chloroethyl chloridocarbonate
2-Chloroethyl chlorocarbonate
beta-chloroethylchlorocarbonate
Carbonochloridicacid,2-chloroethylester
Carbonochloridicacid2-chloroethylester
chlorocarbonicacid2-chloro-ethylester
Chloroformic acid beta-chloroethyl ester
chloro-formicaci2-chloroethylester
chloroformicacid,beta-chloroethylester
Formic acid, chloro-, 2-chloroethyl ester
TL 207
tl207
[EINECS(EC#)]

210-982-4
[Molecular Formula]

C3H4Cl2O2
[MDL Number]

MFCD00000646
[Molecular Weight]

142.97
[MOL File]

627-11-2.mol
Chemical PropertiesBack Directory
[Melting point ]

<25 °C
[Boiling point ]

155-156°C
[density ]

1.385
[vapor pressure ]

0.23 psi ( 20 °C)
[refractive index ]

1.446
[Fp ]

158°F
[storage temp. ]

Refrigerator
[solubility ]

soluble in Ether,Benzene,Acetone
[form ]

Liquid
[color ]

Colorless to yellow
[BRN ]

506639
[Henry's Law Constant]

9.0×10-3 mol/(m3Pa) at 25℃, HSDB (2015)
[InChIKey]

SVDDJQGVOFZBNX-UHFFFAOYSA-N
[CAS DataBase Reference]

627-11-2(CAS DataBase Reference)
[NIST Chemistry Reference]

Carbonochloridic acid, 2-chloroethyl ester(627-11-2)
[EPA Substance Registry System]

627-11-2(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
[Signal word ]

Danger
[Hazard statements ]

H314-H331
[Precautionary statements ]

P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
[Hazard Codes ]

T
[Risk Statements ]

R23:Toxic by inhalation.
R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

3277
[WGK Germany ]

3
[RTECS ]

LQ5950000
[TSCA ]

TSCA listed
[REACH Registrations]

Active
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[HS Code ]

29159000
[Safety Profile]

Poison by inhalation. May also cause fatahties by ingestion or skin contact. May cause burns to the eyes and skin. When heated to decomposition it emits toxic fumes of Cl-
[Hazardous Substances Data]

627-11-2(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->2-Chloroethanol-->Flow Cell
[Preparation Products]

Vinyl chloroformate-->2-Nitro-N-hydroxyethyl aniline-->1,1-Dichloroethane-->2-chloroethyl N-(3-chlorophenyl)carbamate
Hazard InformationBack Directory
[General Description]

Liquid.
[Reactivity Profile]

CHLOROETHYL CHLOROFORMATE is an acid halide. Acid halides are water reactive; some are violently reactive. They are incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
[Air & Water Reactions]

Decomposed slowly by water forming ethanol, HCl, and CO2; on contact with moist air, CHLOROETHYL CHLOROFORMATE(627-11-2) gives off HCl fumes; attacks many metals especially in humid atmosphere. REF [Handling Chemicals Safely, 1980. p. 476].
[Health Hazard]

(Non-Specific--Ethyl Chloroformate) Poisonous; may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes.
[Chemical Properties]

Clear colorless liquid
[Uses]

2-Chloroethyl Chloroformate is a reactant used in the preparation of artemisinin-derived dimer carbonates and thiocarbonates with antimalarial activity.
[Purification Methods]

Purify it by fractional distillation, preferably in a vacuum and store it in a dry atmosphere. [Jones J Chem Soc 2735 1957, Beilstein 3 IV 24.]
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Chloroethyl chloroformate(627-11-2).msds
Spectrum DetailBack Directory
[Spectrum Detail]

2-Chloroethyl chloroformate(627-11-2)MS
2-Chloroethyl chloroformate(627-11-2)1HNMR
2-Chloroethyl chloroformate(627-11-2)13CNMR
2-Chloroethyl chloroformate(627-11-2)IR1
2-Chloroethyl chloroformate(627-11-2)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

627-11-2(sigmaaldrich)
[TCI AMERICA]

2-Chloroethyl Chloroformate,>98.0%(T)(627-11-2)
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