| Identification | More | [Name]
Bromoacetaldehyde diethyl acetal | [CAS]
2032-35-1 | [Synonyms]
1,1-DIETHOXY-2-BROMOETHANE
2,2-DIETHOXYETHYL BROMIDE
2-BROMO-1,1-DIETHOXYETHANE
BADEA
BROMOACETAL
BROMOACETALDEHYDE DIETHYL ACETAL
BROMO ACETYL DIACETAL
1-Bromo-2,2-diethoxyethane
2-bromo-1,1-diethoxy-ethan
2-Bromoacetaldehyde diethyl acetal
Acetaldehyde, bromo-, diethyl acetal
Bromacetal
bromoacetaldehydedlethylacetal
-Bromodiethylacetal
Diethyl bromoacetal
Diethyl bromoacetaldehyde acetal
Betabromoacetaldehyde diethylacetal
BROMOACETALDEHYDE DIETHYL ACETAL, STAB.
Bromoacetaldehydediethylacetate
Ethane, 2-bromo-1,1-diethoxy- | [EINECS(EC#)]
217-989-1 | [Molecular Formula]
C6H13BrO2 | [MDL Number]
MFCD00000214 | [Molecular Weight]
197.07 | [MOL File]
2032-35-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless to light yellow liqui | [Boiling point ]
66-67 °C18 mm Hg(lit.)
| [density ]
1.31 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.439(lit.)
| [Fp ]
125 °F
| [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oil | [color ]
Clear Colourless | [Specific Gravity]
1.310 | [Water Solubility ]
immiscible | [Sensitive ]
Moisture Sensitive | [BRN ]
635754 | [InChI]
1S/C6H13BrO2/c1-3-8-6(5-7)9-4-2/h6H,3-5H2,1-2H3 | [InChIKey]
LILXDMFJXYAKMK-UHFFFAOYSA-N | [SMILES]
CCOC(CBr)OCC | [CAS DataBase Reference]
2032-35-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethane, 2-bromo-1,1-diethoxy-(2032-35-1) | [Storage Precautions]
Light sensitive | [EPA Substance Registry System]
Ethane, 2-bromo-1,1-diethoxy- (2032-35-1) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301-H315-H319-H330 | [Precautionary statements ]
P301+P310+P330-P302+P352-P304+P340+P310-P305+P351+P338 | [Hazard Codes ]
Xi,T | [Risk Statements ]
R10:Flammable.
R36:Irritating to the eyes.
R36/38:Irritating to eyes and skin .
R23:Toxic by inhalation.
R22:Harmful if swallowed. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S38:In case of insufficient ventilation, wear suitable respiratory equipment .
S37/39:Wear suitable gloves and eye/face protection .
S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [F ]
8-9-21 | [Hazard Note ]
Toxic/Irritant | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29110000 | [Storage Class]
6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | [Hazard Classifications]
Acute Tox. 2 Inhalation
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Bromine-->Vinyl acetate | [Preparation Products]
Thianaphthene-->1-Benzofuran-5-carbaldehyde-->Benzofuran-5-boronic acid-->3-Bromo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine-->7-(Trifluoromethyl)-3-iodoimidazo[1,2-a]pyrimidine-->7-Bromo-3-trifluoromethyl-imidazo[1,2-b][1,2,4]triazine-->1-Benzofuran-5-carbonitrile-->5-Bromo-1-benzofuran-->Benzo[b]thiophen-5-yl-5-boronic acid-->4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-->5-Methyl-1-benzothiophene-2-carbaldehyde-->5-Methoxybenzofuran-->Pyrrolo[2,3-d]pyrimidin-4-ol-->3,3-Diphenyltetrahydrofuran-2-ylidene(dimethyl)ammonium bromide-->5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97%-->6-Bromoimidazo[1,2-a]pyridine-->6-Bromo-benzo[b]thiophene-->5-Methylindole-->6,8-Dibromoimidazo[1,2-a]pyrazine-->3-(p-Chlorophenyl)-3-(2-pyridyl)propylaldehyde diethyl acetal-->1,1'-oxybis[2,2-diethoxyethane]-->Chlorphenamine maleate-->(2,2-diethoxyethyl)methylamine |
| Questions And Answer(Q&A) | Back Directory | [Preparation]
To a flask containing 118.0 gm (1.0 mole) of diethyl acetal and 55 gm (0.55 mole) of calcium carbonate is dropwise added 55 ml (1.0 mole) of bromine over a 30-45 min period while keeping the reaction temperature at 5°-10°C. The reaction mixture is allowed to stand 24 hr, steam is introduced to dissolve the salts, the oil separated, dried over potassium carbonate, and distilled to afford 61-83 gm (31-42%), b.p. 167°-170°C. The product is further purified by shaking with potassium carbonate and distilling it under reduced pressure, b.p. 48°-49°C (3 mm Hg). The pure acetal is unstable and becomes colored in a few hours and black after several days. However, the crude acetal boiling at 167°-170°C is stable for several months.
|
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liqui | [Uses]
Bromoacetaldehyde diethyl acetal, is used as a synthetic building block. It is mainly used for synthesis of antibiotics such as erythromycin and cephalosporins and to other drugs. It also can be used as pharmaceutical intermediates. Besides, this chemical can be used to pruduce drugs such as methylthio imidazole, chlorpheniramine and others for thyroid. It also acts as a Useful intermediate for the preparation of other ?-heterosubstituted acetaldehyde acetals. | [Uses]
Synthetic building block1,2 | [General Description]
May darken in storage |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|