ChemicalBook--->CAS DataBase List--->2375-03-3

2375-03-3

2375-03-3 Structure

2375-03-3 Structure
IdentificationMore
[Name]

6alpha-Methylprednisolone sodium succinate
[CAS]

2375-03-3
[Synonyms]

1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-SUCCINATE, SODIUM SALT
(6alpha,11beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione monosodium salt
6ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 21-HEMISUCCINATE SODIUM SALT
6ALPHA-METHYLPREDNISOLONE 21-HEMISUCCINATE SODIUM SALT
6-ALPHA-METHYLPREDNISOLONE SODIUM SUCCINATE
METHPREDNISOLONE SODIUM SUCCINATE
METHYLPREDNISOLONE SODIUM SUCCINATE
11-beta,17,21-trihydroxy-6-alpha-methyl-1,4-pregnadiene-3,20-dione21-(sodium
4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-(hyd
6a-methylprednisolone21-hemisuccinate*sodium
rogensuccinate),monosodiumsalt
solu-medrol
solu-medrone
succinate)
u9088
urbasonsolubile
Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, monosodium salt, (6alpha,11beta)-
Methylprodnisolone Sodium Succinate
Methylprednisolone Succinate BP93,USP26
6α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate
[EINECS(EC#)]

219-156-8
[Molecular Formula]

C48H64Na2O14
[MDL Number]

MFCD00152612
[Molecular Weight]

910.99
[MOL File]

2375-03-3.mol
Chemical PropertiesBack Directory
[Melting point ]

>186°C (dec.)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

lyophilized powder
[color ]

White to Off-White
[CAS DataBase Reference]

2375-03-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

R61:May cause harm to the unborn child.
R40:Limited evidence of a carcinogenic effect.
[Safety Statements ]

S53:Avoid exposure-obtain special instruction before use .
S22:Do not breathe dust .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[WGK Germany ]

3
[RTECS ]

TU4154060
[Toxicity]

LD50 oral in rat: > 5gm/kg
Hazard InformationBack Directory
[Uses]

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.
[Uses]

6α-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries.
[Definition]

ChEBI: Methylprednisolone sodium succinate is a corticosteroid hormone.
[Brand name]

A-Methapred (Abbott); A-Methapred (Hospira); Solu-Medrol (Pharmacia & Upjohn).
[Biochem/physiol Actions]

Glucocorticoid with slightly longer half-life than that of prednisolone.
Spectrum DetailBack Directory
[Spectrum Detail]

6alpha-Methylprednisolone sodium succinate(2375-03-3)MS
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

2375-03-3(sigmaaldrich)
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