| Identification | More | [Name]
Methyl 4-amino-2-methoxybenzoate | [CAS]
27492-84-8 | [Synonyms]
4-AMINO-2-METHOXYBENZOIC ACID METHYL ESTER
METHYL 4-AMINO-2-METHOXYBENZENECARBOXYLATE
METHYL 4-AMINO-2-METHOXYBENZOATE
methyl 4-amino-o-anisate
Methyl 4-amino-2-methoxybenzoate, 95+%
4-Amino-o-anisic acid methyl ester | [EINECS(EC#)]
248-494-9 | [Molecular Formula]
C9H11NO3 | [MDL Number]
MFCD00017202 | [Molecular Weight]
181.19 | [MOL File]
27492-84-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
155-159 °C (lit.) | [Boiling point ]
339.2±22.0 °C(Predicted) | [density ]
1.179±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
2.04±0.10(Predicted) | [color ]
White | [InChI]
InChI=1S/C9H11NO3/c1-12-8-5-6(10)3-4-7(8)9(11)13-2/h3-5H,10H2,1-2H3 | [InChIKey]
YUPQMVSYNJQULF-UHFFFAOYSA-N | [SMILES]
C(OC)(=O)C1=CC=C(N)C=C1OC | [CAS DataBase Reference]
27492-84-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
2
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2916399090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Grey Solid | [Uses]
An intermediate in the synthesis of Metoclopramide | [Synthesis]
Methyl 2-methoxy-4-nitrobenzoate (700 mg, 3.3 mmol) was used as a raw material for a catalytic hydrogenation reaction in methanol (10 mL) with the addition of 5% Pd-C (100 mg) and Na2SO4 (100 mg) as a catalyst for 1 h at 50 psi hydrogen pressure. Upon completion of the reaction, methyl 2-methoxy-4-aminobenzoate (600 mg, quantitative yield) was obtained and the product was a white solid. | [References]
[1] Patent: US2015/266828, 2015, A1. Location in patent: Paragraph 1023
[2] Patent: WO2016/53794, 2016, A1. Location in patent: Page/Page column 125
[3] Patent: WO2015/6100, 2015, A1. Location in patent: Page/Page column 176
[4] Proceedings - Indian Academy of Sciences, Section A, 1950, vol. 32, p. 357,362
[5] Journal of the American Chemical Society, 1952, vol. 74, p. 592,595 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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| Telephone: |
0573-85285100 18627885956 |
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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