| Identification | Back Directory | [Name]
Nicomol | [CAS]
27959-26-8 | [Synonyms]
K-31
nicomol
Atomirate
Cholexamin
2,2,6,6-Tetrakis(nicotinoyloxymethyl)cyclohexanol
[2-hydroxy-1,3,3-tris(pyridin-3-ylcarbonyloxyMethyl)cyclohexyl]M
2-Hydroxy-1,1,3,3-cyclohexanetetramethanol 1,1,3,3-tetranicotinate
(2-Hydroxycyclohexane-1,1,3,3-tetrayl)tetrakis(methylene) tetranicotinate
nicotin [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl ester
[2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl pyridine-3-carboxylate
[2-hydroxy-1,3,3-tris(pyridin-3-ylcarbonyloxymethyl)cyclohexyl]methyl pyridine-3-carboxylate
3-Pyridinecarboxylicacid,1,1',1'',1'''-[(2-hydroxy-1,3-cyclohexanediylidene)tetrakis(Methylene)]ester | [EINECS(EC#)]
248-748-9 | [Molecular Formula]
C34H32N4O9 | [MDL Number]
MFCD00865754 | [MOL File]
27959-26-8.mol | [Molecular Weight]
640.64 |
| Chemical Properties | Back Directory | [Melting point ]
177-180° | [Boiling point ]
672.42°C (rough estimate) | [density ]
1.3015 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
Sealed in dry,2-8°C |
| Hazard Information | Back Directory | [Originator]
Cholexamine,Kyorin,Japan,1971 | [Definition]
ChEBI: Nicomol is an organic molecular entity. | [Manufacturing Process]
To a mixture of 60 cc of benzene, 40 cc of pyridine and 17 g of hydrochloric
acid salt of nicotinic acid chloride, was added 4.5 g of 2,2,6,6-
tetramethylolcyclohexanol, and the whole mixture was refuxed at 75°C to
80°C for 2.5 hours. After the mixture was cooled water was added. Precipitate
formed was separated by filtration, washed thoroughly with water and dried.
Recrystallization from dilute acetic acid gave 14 g of the final compound,
melting point 177°C to 180°C. | [Therapeutic Function]
Anticholesteremic |
| Safety Data | Back Directory | [Toxicity]
LD50 in mice, male and female rats (g/kg): >10, 15, <10 orally; >5, >2.5, >2.5 i.p. (Sugawara) |
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
|