| Identification | Back Directory | [Name]
Almitrine dimesylate | [CAS]
29608-49-9 | [Synonyms]
Mesylate AlMitrine
ALMITRINE DIMESYLATE
ALMITRINE DIMESILATE
ALMITRINE BISMESYLATE
Almitrine bismethanesulfonate
2,4-bis(allylamino)-6-[4-[bis(p-fluorophenyl)methyl]-1-piperazinyl]-s-triazine dimethanesulfonate
n,n'-diallyl-6-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1,3,5-triazine-2,4-diamine dimethanesulphonate
N2,N4-Diallyl-6-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine dimethanesulfonate
1,3,5-Triazine-2,4-diamine,6-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-N,N'-di-2-propenyl-,dimethanesulfonate | [EINECS(EC#)]
249-726-1 | [Molecular Formula]
C28H37F2N7O6S2 | [MDL Number]
MFCD01679060 | [MOL File]
29608-49-9.mol | [Molecular Weight]
669.76 |
| Chemical Properties | Back Directory | [Melting point ]
243° (dec) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | [Toxicity]
LD50 in mice: 210 mg/kg i.v., 390 mg/kg i.p., >2 g/kg orally (Regnier) |
| Hazard Information | Back Directory | [Uses]
Respiratory stimulant. | [Definition]
ChEBI: The dimethanesulfonate salt of almitrine. | [Brand name]
Vectarion (Oril S.A., France). | [in vivo]
Almitrine acts via the peripheral arterial chemoreceptors raising carotid sinus nerve output and minute ventilation. Almitrine also has a pulmonary vascular action causing a dose-dependent constriction and dilatation. At low doses Almitrine enhances hypoxic pulmonary vasoconstriction and may improve the overall ventilation/perfusion ratio[2]. | [storage]
Store at -20°C |
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