| Identification | More | [Name]
Methanesulfonamide | [CAS]
3144-09-0 | [Synonyms]
LABOTEST-BB LT00153664
METHANESULFONAMIDE
METHANESULPHANAMIDE
METHANESULPHONAMIDE
METHANSULFONAMIDE
METHYL SULFONAMIDE
METHYL SULFONYLAMINE
Methylsulfonamid
Methanesulfonamide, 98+%
Methanesulphonamide,98+%
Mesyl amide
Methanesulfonyl amide
METHYLSULFAMIDE
Methanesulfonic amide | [EINECS(EC#)]
221-553-6 | [Molecular Formula]
CH5NO2S | [MDL Number]
MFCD00007940 | [Molecular Weight]
95.12 | [MOL File]
3144-09-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White to yellow crystals, powder or flakes | [Melting point ]
85-89 °C(lit.)
| [Boiling point ]
208.2±23.0 °C(Predicted) | [density ]
1.229 (estimate) | [refractive index ]
1.5130 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Slightly soluble in DMSO and methanol. | [form ]
Crystals, Powder or Flakes | [pka]
10.87±0.60(Predicted) | [color ]
White to yellow | [BRN ]
1740835 | [InChI]
InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4) | [InChIKey]
HNQIVZYLYMDVSB-UHFFFAOYSA-N | [SMILES]
CS(N)(=O)=O | [CAS DataBase Reference]
3144-09-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Methane sulfonamide(3144-09-0) | [EPA Substance Registry System]
3144-09-0(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319 | [Precautionary statements ]
P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29350090 |
| Hazard Information | Back Directory | [Chemical Properties]
White to yellow crystals, powder or flakes | [Uses]
Methanesulfonamide will react with thionyl chloride, cyanates, carbon disulfide and ketones and aldehydes to prepare pharmaceuticals, brightening agent and other target molecules. It is also used in biological studies to predict binding affinity and binding mode of protein ligand complexes. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 90, p. 4096, 1968 DOI: 10.1021/ja01017a032
The Journal of Organic Chemistry, 60, p. 7682, 1995 DOI: 10.1021/jo00128a048
Tetrahedron Letters, 35, p. 7201, 1994 DOI: 10.1016/0040-4039(94)85360-6 | [Toxics Screening Level]
The initial threshold screening level (ITSL) for methanesulfonamide is 44 μg/m3 (annual
averaging time). |
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