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532-43-4

532-43-4 Structure

532-43-4 Structure
IdentificationMore
[Name]

Thiamine nitrate
[CAS]

532-43-4
[Synonyms]

3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium nitrate
3-(4-AMINO-2-METHYLPYRIMIDYL-5-METHYL)-4-METHYL-5-(B-HYDROXYETHYL)THIAZOLIUM CHLORIDE MONONITRATE
ANEURINE MONONITRATE
ANEURINE NITRATE
BETABION NITRATE
THIAMINE MONONITRATE
THIAMINE NITRATE
VITAMIN B-1
VITAMIN B1 MONONITRATE
VITAMIN B1 NITRATE
3-(4-amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,beta-hydroxyethylthiazoliu
betabionmononitrate
mnitrate
nitrate(salt)
thiaminenitrate(salt)
Thiaminenitratel
Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate(salt)
vitaminb(sub1)nitrate
Thiamin Mononitrate
Thiaminenitrate,98%
[EINECS(EC#)]

208-537-4
[Molecular Formula]

C12H17N5O4S
[MDL Number]

MFCD00036330
[Molecular Weight]

327.36
[MOL File]

532-43-4.mol
Chemical PropertiesBack Directory
[Appearance]

White or almost white, crystalline powder or small, colourless crystals.
[Melting point ]

374-392 °C
[density ]

1.58 g/cm3
[storage temp. ]

2-8°C
[solubility ]

Sparingly soluble in water, freely soluble in boiling water, slightly soluble in alcohol and in methanol.
[form ]

solid
[pka]

4.8(at 25℃)
[color ]

White to Off-White
[Odor]

wh. cryst. or cryst. powd., sl. char. odor
[Stability:]

Stable. Incompatible with strong oxidizing agents.
[biological source]

synthetic
[Merck ]

9295
[BRN ]

3857790
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
[InChI]

InChI=1S/C12H17N4OS.NO3/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;2-1(3)4/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);/q+1;-1
[InChIKey]

UIERGBJEBXXIGO-UHFFFAOYSA-N
[SMILES]

[N+]1(CC2=CN=C(C)N=C2N)C(C)=C(SC=1)CCO.[N+]([O-])([O-])=O
[Uses]

Vitamin B1.
[CAS DataBase Reference]

532-43-4(CAS DataBase Reference)
[EPA Substance Registry System]

532-43-4(EPA Substance)
Safety DataBack Directory
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

1
[RTECS ]

XI7400000
[TSCA ]

Yes
[HS Code ]

29362200
[Storage Class]

11 - Combustible Solids
[Safety Profile]

Poison by intravenous and intraperitoneal routes. A powerful oxidizer. When heated to decomposition it emits very toxic fums of SOx, and NOx. See also NITRATES.
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ammonium hydroxide-->Quinoline-->Acetamidine hydrochloride-->(2-Methyl-1H-indol-3-yl)-oxo-acetic acid ethyl ester-->Thiamine hydrochloride-->3-Methoxypropionitrile-->Pyramat
[Preparation Products]

Thiamine hydrochloride
Questions And AnswerBack Directory
[Description]

Thiamine nitrate is the thiamine salt formed from one mole of thiamine base and one mole of nitric acid. It occurs as an anhydrous crystalline solid of low hygroscopicity. Thiamin (vitamin B1) is a member of the vitamin B complex. Attributing to low hydroscopicity, thiamine nitrate works as a more stable form of thiamine in pharmaceutical preparations.
Thiamine nitrate is preferred to be used for the preparation of multivitamins and as a food fortification in dry blends and dry products such as in wheat flour.
[References]

[1] Food and Agriculture Organization of the United Nations, Food Fortification: Technology and Quality Control: Report of an FAO technical meeting Rome, 1995
[2] Ronald R. Eitenmiller, W. O. Landen Jr and Lin Ye, Vitamin Analysis for the Health and Food Sciences, Second Edition, 2008
[3] Thomas J. Macek, Beate A. Feller and Edward J. Hanus, Pharmaceutical studies with thiamine mononitrate, Journal of Pharmaceutical Sciences, 1950, vol. 39, 365-369
Hazard InformationBack Directory
[Chemical Properties]

White or almost white, crystalline powder or small, colourless crystals.
[benefits]

Some of the critical uses and benefits of Vitamin B1 Mononitrate(Thiamine nitrate) include:
Supports Energy production: Thiamine nitrate is involved in converting food into energy, particularly in the metabolism of carbohydrates.
Helps Nervous system: Thiamine nitrate is essential for proper nervous system function and is involved in transmitting nerve impulses.
Improves Cardiovascular health: Thiamine nitrate is important for maintaining healthy heart function, and may help to reduce the risk of heart disease.
Supports Appetite regulation: Vitamin B1 mononitrate is involved in regulating appetite and may help to reduce the risk of overeating and weight gain.
Improves Eye health: Thiamine nitrate is involved in maintaining healthy eye function, and may help to reduce the risk of certain eye disorders.
[General Description]

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine Nitrate is a mononitrate salt of thiamine. It is synthesized from thiamine hydrochloride following a sequence of steps. Thiamine Nitrate is used as a dietary supplement in crackers, eggs substitute and enriched flour.
[storage]

Store at 2-8°C, protect from light
Spectrum DetailBack Directory
[Spectrum Detail]

Thiamine nitrate(532-43-4)MS
Thiamine nitrate(532-43-4)1HNMR
Thiamine nitrate(532-43-4)IR1
Thiamine nitrate(532-43-4)IR2
Well-known Reagent Company Product InformationBack Directory
[TCI AMERICA]

Thiamine Nitrate,>98.0%(LC)(E)(532-43-4)
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