| Identification | More | [Name]
Thiamine nitrate | [CAS]
532-43-4 | [Synonyms]
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium nitrate
3-(4-AMINO-2-METHYLPYRIMIDYL-5-METHYL)-4-METHYL-5-(B-HYDROXYETHYL)THIAZOLIUM CHLORIDE MONONITRATE
ANEURINE MONONITRATE
ANEURINE NITRATE
BETABION NITRATE
THIAMINE MONONITRATE
THIAMINE NITRATE
VITAMIN B-1
VITAMIN B1 MONONITRATE
VITAMIN B1 NITRATE
3-(4-amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,beta-hydroxyethylthiazoliu
betabionmononitrate
mnitrate
nitrate(salt)
thiaminenitrate(salt)
Thiaminenitratel
Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate(salt)
vitaminb(sub1)nitrate
Thiamin Mononitrate
Thiaminenitrate,98% | [EINECS(EC#)]
208-537-4 | [Molecular Formula]
C12H17N5O4S | [MDL Number]
MFCD00036330 | [Molecular Weight]
327.36 | [MOL File]
532-43-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White or almost white, crystalline powder or small, colourless crystals. | [Melting point ]
374-392 °C | [storage temp. ]
2-8°C | [solubility ]
Sparingly soluble in water, freely soluble in boiling water, slightly soluble in alcohol and in methanol. | [form ]
solid | [pka]
4.8(at 25℃) | [color ]
White to Off-White | [Odor]
wh. cryst. or cryst. powd., sl. char. odor | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Merck ]
9295 | [BRN ]
3857790 | [InChIKey]
UIERGBJEBXXIGO-UHFFFAOYSA-N | [Uses]
Vitamin B1. | [CAS DataBase Reference]
532-43-4(CAS DataBase Reference) | [EPA Substance Registry System]
532-43-4(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
1 | [RTECS ]
XI7400000 | [TSCA ]
Yes | [HS Code ]
29362200 | [Safety Profile]
Poison by intravenous
and intraperitoneal routes. A powerful
oxidizer. When heated to decomposition it emits very toxic fums of SOx, and NOx. See also NITRATES. |
| Questions And Answer | Back Directory | [Description]
Thiamine nitrate is the thiamine salt formed from one mole of thiamine base and one mole of nitric acid. It occurs as an anhydrous crystalline solid of low hygroscopicity. Thiamin (vitamin B1) is a member of the vitamin B complex. Attributing to low hydroscopicity, thiamine nitrate works as a more stable form of thiamine in pharmaceutical preparations.
Thiamine nitrate is preferred to be used for the preparation of multivitamins and as a food fortification in dry blends and dry products such as in wheat flour.
| [References]
[1] Food and Agriculture Organization of the United Nations, Food Fortification: Technology and Quality Control: Report of an FAO technical meeting Rome, 1995
[2] Ronald R. Eitenmiller, W. O. Landen Jr and Lin Ye, Vitamin Analysis for the Health and Food Sciences, Second Edition, 2008
[3] Thomas J. Macek, Beate A. Feller and Edward J. Hanus, Pharmaceutical studies with thiamine mononitrate, Journal of Pharmaceutical Sciences, 1950, vol. 39, 365-369
|
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white, crystalline powder or small, colourless crystals. | [General Description]
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine Nitrate is a mononitrate salt of thiamine. It is synthesized from thiamine hydrochloride following a sequence of steps. Thiamine Nitrate is used as a dietary supplement in crackers, eggs substitute and enriched flour. | [storage]
Store at 2-8°C, protect from light |
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