| Identification | More | [Name]
2-Amino-5-iodobenzoic acid | [CAS]
5326-47-6 | [Synonyms]
5-IODOANTHRANILIC ACID
TIMTEC-BB SBB001006
2-amino-5-iodo-benzoicaci
5-iodo-anthranilicaci
5-Iodoanthranillic acid
5-iodoanthranil acid
2-AMINO-5-IODOBENZOIC ACID (5-IODOANTHRANILIC ACID)
5-Iodoanthanilic acid | [EINECS(EC#)]
226-205-7 | [Molecular Formula]
C7H6INO2 | [MDL Number]
MFCD00007849 | [Molecular Weight]
263.03 | [MOL File]
5326-47-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
219-221 °C (dec.) (lit.) | [Boiling point ]
383.2±37.0 °C(Predicted) | [density ]
1.8886 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
4.59±0.10(Predicted) | [color ]
Beige or gray to purple | [Water Solubility ]
Soluble in alcohol. Insoluble in water. | [Sensitive ]
Light Sensitive | [BRN ]
639029 | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C7H6INO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11) | [InChIKey]
GOLGILSVWFKZRQ-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC(I)=CC=C1N | [CAS DataBase Reference]
5326-47-6(CAS DataBase Reference) | [Storage Precautions]
Air sensitive;Moisture sensitive | [EPA Substance Registry System]
5326-47-6(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
To the mixture of 2.89 g (18.2 mmol) sodium 2-
aminobenzoate, 40 mL acetic acid and 2.31 g (9.1 mmol) molecular iodine, 5 mL
(44.1 mmol, 30 wt %) aqueous hydrogen peroxide was added drop wise. The
S3
reaction mixture was stirred at 50 °C for 3 h and poured into 400 mL water. The
formed crystals were filtered and recrystallized from benzene to give 2-azido-5-
iodobenzoic acid . IR (suspension in nujol, cm−1
): 3500, 3387, 1670, 1612, 1580,
1541, 1419, 1377, 1319, 1290, 1163, 1125, 813, 688, 619. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
DG2802000
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT, LIGHT SENSITIVE | [HS Code ]
29224999 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2-Amino-5-iodobenzoic acid is used in wide range of medicals industrial applications as well as in human and animal nutrition products such as pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals. | [reaction suitability]
reaction type: solution phase peptide synthesis | [References]
[1] Tetrahedron Letters, 2006, vol. 47, # 28, p. 4793 - 4796
[2] Synlett, 2014, vol. 25, # 1, p. 148 - 152
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006, vol. 45, # 11, p. 2558 - 2565
[4] Medicinal Chemistry Research, 2016, vol. 25, # 6, p. 1125 - 1139
[5] Synthetic Communications, 2008, vol. 38, # 11, p. 1792 - 1798 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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| Telephone: |
0573-85285100 18627885956 |
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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