ChemicalBook--->CAS DataBase List--->5407-87-4

5407-87-4

5407-87-4 Structure

5407-87-4 Structure
IdentificationMore
[Name]

2-Amino-4,6-dimethylpyridine
[CAS]

5407-87-4
[Synonyms]

2-AMINO-4,6-DIMETHYLPYRIDINE
2-AMINO-4,6-LUTIDINE
4,6-DIMETHYL-2-LUTIDINE
4,6-DIMETHYLPYRIDIN-2-AMINE
4,6-DIMETHYL-PYRIDIN-2-YLAMINE
6-AMINO-2,4-LUTIDINE
LABOTEST-BB LT00080724
2,4-Lutidine, 6-amino-
2-Amino-4,6-dimethylpuridine
2-amino-4,6-dimethyl-pyridin
4,6-Dimethyl-2-aminopyridine
4,6-dimethyl-2-pyridinamin
4,6-Dimethyl-2-pyridinamine
Pyridine, 2-amino-4,6-dimethyl-
4,6-dimethyl-2-pyridylamine
6-AMINO-2,4-LUTIDINE 98+%
2-amino-4,6-dimethylpyridine (6-amino-2,4,-lutidine)
2,4-Dimethyl-6-aminopyridine
[EINECS(EC#)]

226-470-9
[Molecular Formula]

C7H10N2
[MDL Number]

MFCD00006322
[Molecular Weight]

122.17
[MOL File]

5407-87-4.mol
Chemical PropertiesBack Directory
[Melting point ]

63-64 °C (lit.)
[Boiling point ]

235 °C (lit.)
[density ]

1.0959 (rough estimate)
[refractive index ]

1.6100 (estimate)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[form ]

Crystalline Powder
[pka]

7.62±0.35(Predicted)
[color ]

White to light brown
[InChI]

InChI=1S/C7H10N2/c1-5-3-6(2)9-7(8)4-5/h3-4H,1-2H3,(H2,8,9)
[InChIKey]

BRBUBVKGJRPRRD-UHFFFAOYSA-N
[SMILES]

C1(N)=NC(C)=CC(C)=C1
[CAS DataBase Reference]

5407-87-4(CAS DataBase Reference)
[NIST Chemistry Reference]

2-Pyridinamine, 4,6-dimethyl-(5407-87-4)
[EPA Substance Registry System]

5407-87-4(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[RTECS ]

US1818000
[Hazard Note ]

Irritant
[TSCA ]

TSCA listed
[HS Code ]

2933399990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Xylene-->Sodium amide-->2,4-Lutidine
[Preparation Products]

2-BROMO-4,6-DIMETHYLPYRIDINE-->CARBAMIC ACID, N-(4,6-DIMETHYL-2-PYRIDINYL)-,1,1-DIMETHYLETHYL ESTER-->Ethyl N-(4,6-dimethylpyridin-2-yl)carbamate-->JM 42-->Propanamide, N-(4,6-dimethyl-2-pyridinyl)-
Hazard InformationBack Directory
[Chemical Properties]

White to off-white crystalline
[Uses]

Organic intermediate.
[Application]

2-Amino-4,6-dimethylpyridine is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandins and leukotrienes. 2-Amino-4,6-dimethylpyridine binds to the cyclooxygenase enzyme and blocks its conversion of arachidonic acid to prostaglandin H2. This compound has been shown to have potent inhibitory effects against Leishmania, with high values in reactive compounds. The molecular modeling of this compound shows that it has an unpaired amino function and an amide.
[Purification Methods]

Recrystallise this base from hexane, ether/pet ether or *benzene. Residual *benzene is removed over paraffin-wax chips in an evacuated desiccator. The dipicrate crystallises from EtOH and has m 205-207o(dec). [Beilstein 22 III/IV 4210.]
Spectrum DetailBack Directory
[Spectrum Detail]

2-Amino-4,6-dimethylpyridine(5407-87-4)1HNMR
2-Amino-4,6-dimethylpyridine(5407-87-4)13CNMR
2-Amino-4,6-dimethylpyridine(5407-87-4)IR1
2-Amino-4,6-dimethylpyridine(5407-87-4)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

5407-87-4(sigmaaldrich)
[TCI AMERICA]

6-Amino-2,4-lutidine,>98.0%(T)(5407-87-4)
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