ChemicalBook--->CAS DataBase List--->5570-77-4

5570-77-4

5570-77-4 Structure

5570-77-4 Structure
IdentificationMore
[Name]

4-Chloro-N-methylpiperidine
[CAS]

5570-77-4
[Synonyms]

1-METHYL-4-CHLORO-PIPERIDINE
4-CHLORO-1-METHYLPIPERIDINE
4-CHLORO-N-METHYL PIPERIDINE
N-METHYL-4-CHLORO PIPERIDINE
4-chloro-1-methyl-piperidin
N-METHYL 4 CHLORO PIPERIDINE BASE
N-Methyl-4-Chloropiperdine/4-Chloro-1-Methylpiperidine
N-Methyl-4-chloro
4-CHLORO-N-METHYLPIPERIDINE HYDROCHLORIDE 97%
[EINECS(EC#)]

226-942-4
[Molecular Formula]

C6H12ClN
[MDL Number]

MFCD00044489
[Molecular Weight]

133.62
[MOL File]

5570-77-4.mol
Chemical PropertiesBack Directory
[Melting point ]

160-165°C
[Boiling point ]

162°C(lit.)
[density ]

1.02
[vapor pressure ]

3.493hPa at 25℃
[refractive index ]

1.4670-1.4710
[Fp ]

48 °C
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

Chloroform (Slightly), Ethanol (Slightly) , Methanol (Slightly)
[form ]

clear liquid to slightly cloudy liquid
[pka]

7.88±0.10(Predicted)
[color ]

Colorless to Light yellow to Light orange
[Water Solubility ]

1.533g/L at 29℃
[InChIKey]

MYGXGCCFTPKWIH-UHFFFAOYSA-N
[LogP]

1.318 at 25℃
[CAS DataBase Reference]

5570-77-4(CAS DataBase Reference)
[EPA Substance Registry System]

5570-77-4(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

10-34-36/38
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[RIDADR ]

1993
[HazardClass ]

3
[PackingGroup ]

III
[HS Code ]

29333990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Thionyl chloride-->4-Hydroxypiperidine-->1-Methyl-4-piperidone
[Preparation Products]

4-Chloro-1-methylpiperidine hydrochloride-->1-(1-Methyl-4-piperidinyl)piperazine-->1-Methylpiperdin-4-ylmagnesium chloride, 0.50 M in THF-->4-Chloropiperidine-->4-Piperidinesulfonamide, 1-methyl-
Hazard InformationBack Directory
[Chemical Properties]

Clear colorless liquid
[Uses]

4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.
[Flammability and Explosibility]

Notclassified
[Physiological effects]

4-Chloro-N-methylpiperidine can be used to treat bronchial asthma, chronic obstructive pulmonary disease, and other respiratory disorders by inhibiting the production of histamine in the body. It also has antihistaminic effects that may be due to its ability to inhibit histamine release from mast cells or block H1 receptors.
Spectrum DetailBack Directory
[Spectrum Detail]

4-Chloro-N-methylpiperidine(5570-77-4)MS
4-Chloro-N-methylpiperidine(5570-77-4)13CNMR
4-Chloro-N-methylpiperidine(5570-77-4)IR1
4-Chloro-N-methylpiperidine(5570-77-4)IR2
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