| Identification | More | [Name]
D-Glutamine | [CAS]
5959-95-5 | [Synonyms]
D-2-AMINOGLUTARAMIC ACID
D(-)-GLUTAMIC ACID-5-AMIDE
D-GLUTAMIC ACID 5-AMIDE
D(-)-GLUTAMINE
D-GLUTAMINE
D-GLUTAMINIC ACID 5-AMIDE
H-D-GLN-OH
(R)-2-AMINO-4-CARBAMOYL-BUTYRIC ACID
(2R)-2-amino-4-carbamoyl-butanoic acid
D-Glutamine (9CI)
Glutamine,D-(8Cl)
D-Gln-OH
D-GLUTAMINE extrapure
D-2-Aminoglutaramic acid, D-Glutamic acid 5-amide
Citric Acid, Monohydrate, Crystal, Reagent
D-Gln | [EINECS(EC#)]
673-968-0 | [Molecular Formula]
C5H10N2O3 | [MDL Number]
MFCD00065607 | [Molecular Weight]
146.14 | [MOL File]
5959-95-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystalline powder | [Melting point ]
184-185 °C | [alpha ]
-32 º (589nm, c=10, N HCl) | [Boiling point ]
265.74°C (rough estimate) | [density ]
1.3394 (rough estimate) | [refractive index ]
-33 ° (C=5, 5mol/L HCl) | [storage temp. ]
-15°C | [solubility ]
Water (Slightly, Sonicated) | [form ]
Powder | [pka]
2.27±0.10(Predicted) | [color ]
White | [Water Solubility ]
42.53g/L(temperature not stated) | [BRN ]
1723796 | [InChIKey]
ZDXPYRJPNDTMRX-GSVOUGTGSA-N | [LogP]
-1.576 (est) | [CAS DataBase Reference]
5959-95-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing . | [WGK Germany ]
3
| [HS Code ]
29241990 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
D-Glutamine is an unnatural isomer of L-Glutamine (G597000) that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well. It is often used to determine the activity of Glutamine synthetase, an enzyme that is commonly found in the mammalian liver and brain that controls the use of nitrogen in cells. | [Definition]
ChEBI: The D-enantiomer of glutamine. | [General Description]
Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids. | [Biochem/physiol Actions]
Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%. |
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