| Identification | More | [Name]
5-Nitro-2-furoic acid | [CAS]
645-12-5 | [Synonyms]
2-CARBOXY-5-NITROFURAN
5-NITRO-2-FURANCARBOXYLIC ACID
5-NITRO-2-FUROIC ACID
RARECHEM AL BO 1619
2-Furancarboxylic acid, 5-nitro-
2-furancarboxylicacid,5-nitro
2-Furoic acid, 5-nitro-
5-nitro-2-furoicaci
5-Nitrofurancarboxylic acid
5-nitrofurancarboxylicacid
5-Nitrofuroic acid
5-nitrofuroicacid
5-nitropyromucate
5-Nitropyromucic acid
Nitrofurate
5-Nitrofuran-2-carboxylic acid
5-Nitro-2-furoic acid, 98+%
5-Nitro-2-furylcarboxylic acid | [EINECS(EC#)]
211-432-6 | [Molecular Formula]
C5H3NO5 | [MDL Number]
MFCD00003240 | [Molecular Weight]
157.08 | [MOL File]
645-12-5.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow crystalline powder | [Melting point ]
185-189 °C (lit.) | [Boiling point ]
281.7°C (rough estimate) | [density ]
1.8109 (rough estimate) | [refractive index ]
1.4798 (estimate) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.06±0.10(Predicted) | [color ]
White to Light Yellow | [Water Solubility ]
Slightly soluble in water. | [BRN ]
139373 | [InChI]
InChI=1S/C5H3NO5/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8) | [InChIKey]
IODMEDPPCXSFLD-UHFFFAOYSA-N | [SMILES]
O1C([N+]([O-])=O)=CC=C1C(O)=O | [CAS DataBase Reference]
645-12-5(CAS DataBase Reference) | [NIST Chemistry Reference]
5-Nitrofuran-2-carboxylic acid(645-12-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R68:Possible risk of irreversible effects.
R36/37/38:Irritating to eyes, respiratory system and skin .
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S36/37:Wear suitable protective clothing and gloves .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [WGK Germany ]
3
| [RTECS ]
LV2012000
| [HS Code ]
2932.19.5100 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow crystalline powder | [Uses]
5-Nitro-2-furoic acid was used in the preparation of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles. | [Uses]
5-Nitro-2-furoic acid is a representative of 2-substituted
5-nitrofurans. A number of nitrofurans have been used as
antibacterial, antiprotozoal, and anthelmintic drugs in
humans and animals. 2-Substituted 5-nitrofurans have been
used worldwide as human and veterinary medicines, food
preservatives, and feed additives, and they are utilized in
human medicine as antibacterial agents. Therefore, the relationship
between the antibacterial effect and the mutagenicity
of these compounds and their oxidized metabolites is
important. Comparison of the antibacterial effects and genotoxic
potencies of nitrofuran drugs and their oxidative
metabolites may provide a new direction for selecting nitrofuran
drugs for human use. | [Uses]
5-Nitro-2-furoic acid was used in the preparation of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles. The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid has also been studied. | [General Description]
The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid has been studied. | [Environmental Fate]
5-Nitro-2-furoic acid is a yellow crystalline powder with molecular
weight of 157.08 g mol-1 and density of 1.72 g cm-3. The
boiling point is 332.4 ℃ and the melting point is 185.00–
189.00 ℃ at 760 mm Hg. Vapor pressure is 5.83E-05 mm Hg
at 25 ℃ and enthalpy of vaporization is 60.71 kJ mol-1.
5-Nitro-2-furoic acid is very soluble in water. It is stable under
normal temperature and pressure. | [Toxicity evaluation]
The toxicological properties of this compound have not been
fully investigated. However, as a minimum precaution, it
should be considered harmful. Precautions should be taken
and procedures adopted to prevent exposure. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|