| Identification | More | [Name]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone | [CAS]
7226-23-5 | [Synonyms]
1,3-DIMETHYL-2-OXOHEXAHYDROPYIRIMIDINE
1,3-DIMETHYL-3,4,5,6-TETRAHYDRO-2(1H)-PYRIMIDINONE
1,3-DIMETHYL-PROPYLENEUREA
1,3-DIMETHYLTETRAHYDRO-2-PYRIMIDINONE
DIMETHYL(1,3-)-3,4,5,6-TETRAHYDRO-2H-PYRIMIDONE
DIMETHYLPROPYLENE UREA
DMPU
LABOTEST-BB LT00848352
N,N'-DIMETHYL-N,N'-TRIMETHYLENEUREA
N,N'-DIMETHYLPROPYLENEUREA
1,3-dimethyl-perhydro-2-pyrimidinone
1,3-dimethyl-tetrahydro-pyrimidin-2-one
n,n’-dimethyltrimethyleneurea
tetrahydro-1,3-dimethyl-2(1h)pyrimidine
tetrahydro-1,3-dimethyl-2(1h)-pyrimidinon
1,3-Dimethyl-2-oxohexahydropyrimidine
1,3-Dimethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one
tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one
N,N'-Dimethyl-N,N'-trimethyleneurea (DMPU)
1,3-DIMETHYL-3,4,5,6-TETRAHYDRO-2(1H)-PY RIMIDINONE ABS. | [EINECS(EC#)]
230-625-6 | [Molecular Formula]
C6H12N2O | [MDL Number]
MFCD00006550 | [Molecular Weight]
128.17 | [MOL File]
7226-23-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to slightly yellowish liquid | [Melting point ]
-20 °C
| [Boiling point ]
146 °C44 mm Hg(lit.)
| [density ]
1.06 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.5 hPa (57 °C) | [refractive index ]
n20/D 1.488(lit.)
| [Fp ]
121 °C
| [storage temp. ]
Store below +30°C. | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Liquid | [pka]
-0.65±0.20(Predicted) | [color ]
Clear colorless to slightly yellow | [PH]
11 (100g/l, H2O, 20℃) | [explosive limit]
1.6-9.3%(V) | [Water Solubility ]
soluble | [Sensitive ]
Hygroscopic | [Detection Methods]
GC | [BRN ]
110562 | [Dielectric constant]
36.119999999999997 | [Stability:]
Hygroscopic | [Major Application]
peptide synthesis | [InChI]
1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3 | [InChIKey]
GUVUOGQBMYCBQP-UHFFFAOYSA-N | [SMILES]
CN1CCCN(C)C1=O | [LogP]
0.05 at 25℃ | [CAS DataBase Reference]
7226-23-5(CAS DataBase Reference) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl- (7226-23-5) |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS05,GHS07,GHS08 | [Signal word ]
Danger | [Hazard statements ]
H302-H318-H361f | [Precautionary statements ]
P201-P280-P301+P312+P330-P305+P351+P338+P310-P308+P313 | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes.
R43:May cause sensitization by skin contact.
R62:Possible risk of impaired fertility.
R41:Risk of serious damage to eyes. | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
2
| [RTECS ]
UW7582500
| [F ]
3-10 | [Autoignition Temperature]
255 °C | [TSCA ]
Yes | [HS Code ]
29335995 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1
Repr. 2 | [Toxicity]
LD50 orally in Rabbit: 1770 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is clear colorless to slightly yellowish liquid
| [Uses]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is a versatile organic solvent in and less toxic than HMPA. It is mainly applied in the synthesis of pharmaceuticals and agrochemicals. DMPU is also used in the electronics industry.
| [Flammability and Explosibility]
Nonflammable(100%) | [Synthesis]
The general procedure for the synthesis of N,N-dimethylpropenyl urea and compounds (CAS:96690-06-1) from carbon dioxide, 1,3-dichloropropane and monomethylamine was as follows: 1.24 g of aqueous 1,3-dichloropropane and 5.15 g of a 40% aqueous solution of methylamine were added to a pressure vessel made of 20 mL of SUS316. At a pressure of about 0.5 MPa, 1.95 g of carbon dioxide gas was passed into the vessel. Subsequently, the reaction mixture was reacted at a constant temperature at 120°C for 2 hours. At the end of the reaction, 3-methyl-1,3-oxazin-2-one was obtained in 15% yield, as well as 1,3-dimethyltetrahydropyrimidin-2(1H)-one in 64% yield. | [References]
[1] Patent: US2005/154200, 2005, A1. Location in patent: Page/Page column 4 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone(7226-23-5)MS
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone(7226-23-5)1HNMR
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone(7226-23-5)13CNMR
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone(7226-23-5)IR1
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone(7226-23-5)Raman
|
| Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 97%(7226-23-5) | [Alfa Aesar]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 98+%(7226-23-5) | [Sigma Aldrich]
7226-23-5(sigmaaldrich) | [TCI AMERICA]
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone,>98.0%(GC)(7226-23-5) |
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