| Identification | More | [Name]
4-Methylmorpholine N-oxide | [CAS]
7529-22-8 | [Synonyms]
4-METHYLMORPHOLINE 4-OXIDE
4-METHYLMORPHOLINE N-OXIDE
N-METHYLMORPHOLINE 4-OXIDE
NMO
4-methyl-morpholin4-oxide
Morpholine, 4-methyl-, 4-oxide
Morpholine,4-methyl-,4-oxide
N-Methylmorpholine oxide
METHYL MORPHOLINE OXIDE
4-METHYLMORPHOLINE N-OXIDE, 50 WT. % SOL UTION IN WATER
4-METHYLMORPHOLINE-4-OXIDE SOLUTION, ~50 % IN WATER
N-MethylMorpholineOxide50%(Nmmo)
4-MethlMorpholine-N-Oxide99%
N-Methyl morpholine-N-oxide, 60% w/w soln. in water
N-MethylMorpholineOxide(NMMO)
N-MethylmorpholineN-oxide,50%w/waq.soln.
4-methylmorpholine n-oxide solution
nmo solution
N-METHYLMORPHOLINE N-OXIDE: 50% W/W AQUEOUS SOLUTION
4-Methylmorpholine oxide | [EINECS(EC#)]
231-391-8 | [Molecular Formula]
C5H11NO2 | [MDL Number]
MFCD00005947 | [Molecular Weight]
117.15 | [MOL File]
7529-22-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to yellow solution | [Melting point ]
180-184 °C(lit.)
| [Boiling point ]
118-119°C | [density ]
1,14 g/cm3 | [vapor pressure ]
1.41hPa at 20℃ | [refractive index ]
n20/D 1.43
| [Fp ]
118-119°C | [storage temp. ]
2-8°C | [solubility ]
DMSO (Soluble), Methanol (Slightly) | [form ]
Liquid | [pka]
4.93±0.20(Predicted) | [color ]
Clear colorless to yellow | [PH]
9.00 ( in neat) | [Water Solubility ]
Soluble in water, methanol, ethanol, acetone, ethers and dimethylsulfoxide. | [BRN ]
507437 | [Stability:]
Hygroscopic | [Cosmetics Ingredients Functions]
SURFACTANT - FOAM BOOSTING
SURFACTANT - CLEANSING
CLEANSING | [InChI]
1S/C5H11NO2/c1-6(7)2-4-8-5-3-6/h2-5H2,1H3 | [InChIKey]
LFTLOKWAGJYHHR-UHFFFAOYSA-N | [SMILES]
C[N+]1([O-])CCOCC1 | [LogP]
-1.2 at 25℃ | [CAS DataBase Reference]
7529-22-8(CAS DataBase Reference) | [NIST Chemistry Reference]
N-Methylmorpholine-N-oxide(7529-22-8) | [EPA Substance Registry System]
7529-22-8(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS02,GHS03,GHS08 | [Signal word ]
Danger | [Hazard statements ]
H228-H272-H361f | [Precautionary statements ]
P202-P210-P220-P240-P241-P308+P313 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
1
| [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29349990 | [Storage Class]
4.1B - Flammable solid hazardous materials | [Hazard Classifications]
Flam. Sol. 1
Repr. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to yellow solution | [Uses]
4-Methylmorpholine N-Oxide is a metabolite of Morpholine (M723725). N-Methylmorpholine N-Oxide is commonly used to dissolve cellulose as well as in the dissolution of of scleroproteins. | [Definition]
ChEBI: N-methylmorpholine N-oxide is a morpholine N-oxide resulting from the oxidation of the amino group of N-methylmorpholine. | [General Description]
4-Methylmorpholine?N-oxide is an organic compound used as a co-oxidant along with OsO4 and ruthenates in organic synthesis. In recent studies, it has been used as a catalyst in silylcyanation of aldehydes and ketones. Lyocell, a regenerated cellulose fiber, can be prepared using 4-methylmorpholine?N-oxide in an eco-friendly manner. | [Flammability and Explosibility]
Flammable | [reaction suitability]
reagent type: oxidant | [Synthesis]
A preparation method of N-methylmorpholine-N-oxide comprises the following steps: (1) adding the nano metal oxide into N-methyl morpholine (NMM) and mixing and stirring to uniformly mix the nano metal oxide with the NMM; (2) dropwise adding a hydrogen peroxide solution into a mixed solution of NMM and a catalyst; (3) raising the temperature to accelerate the reaction process; (4) and (4) filtering and distilling the solution prepared in the step (3) under reduced pressure to obtain the required NMMO solution. The method for preparing NMMO provided by the present disclosure has the advantages of a fast reaction rate, low reaction temperature, few byproducts, etc. | [Purification Methods]
When the oxide is dried for 2-3hours at high vacuum, it dehydrates. Add MeOH to the oxide and distil off the solvent under vacuum until the temperature is ca 95o. Then add Me2CO at reflux and cool to 20o. The crystals are filtered off, washed with Me2CO and dried. The degree of hydration may vary and may be important for the desired reactions. [van Rheenan et al. Tetrahedron Lett 1973 1076, Schneider & Hanze US Pat 2 769 823; see also Sharpless et al. Tetrahedron Lett 2503 1976.] | [References]
[1] Journal of the American Chemical Society, 1980, vol. 102, # 21, p. 6498 - 6503
[2] Patent: EP1348692, 2003, A1. Location in patent: Page/Page column 6-7
[3] Journal of the American Chemical Society, 2003, vol. 125, # 10, p. 2868 - 2869
[4] Patent: EP1348692, 2003, A1. Location in patent: Page/Page column 7
[5] Patent: EP1348692, 2003, A1. Location in patent: Page/Page column 7 |
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J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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