| Identification | More | [Name]
Iron saccharate | [CAS]
8047-67-4 | [Synonyms]
ferric hydroxide sucrose complex
FERRIC OXIDE, SACCHARATED
IRON (III) OXIDE, SACCHARATED
Iron saccharate
saccharated iron oxide
collironi.v.
feojectin
ferricsaccharate
ferricsaccharate...ironoxide(mix.)
ferrivenin
ironoxide,saccharated
ironsugar
iviron
neo-ferrum
proferrin
saccharatedferricoxide
saccharatediron
IronSucrose
Iron(III) saccharate
IRONSUCROSEUSP | [EINECS(EC#)]
232-464-7 | [Molecular Formula]
C18H24Fe2O24 | [MDL Number]
MFCD00166305 | [Molecular Weight]
736.06 | [MOL File]
8047-67-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
168-171°C | [storage temp. ]
Refrigerator | [solubility ]
Water (Slightly) | [form ]
Solid | [color ]
Brown to Dark Brown | [InChI]
InChI=1/3C6H10O8.2Fe/c3*7-1(3(9)5(11)12)2(8)4(10)6(13)14;;/h3*1-4,7-10H,(H,11,12)(H,13,14);;/q;;;2*+3/p-6/t3*1-,2-,3-,4+;;/s3 | [InChIKey]
ADQSUDSYBZBMFT-JMMWHMDLNA-H | [CAS DataBase Reference]
8047-67-4(CAS DataBase Reference) | [IARC]
3 (Vol. 2, Sup 7) 1987 | [EPA Substance Registry System]
8047-67-4(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
Brown solid | [Uses]
Iron Saccharate has been used to treat iron deficiency and iron deficiency anemia associated with different chronic diseases. | [Uses]
Semi-synthetic macrolide antibiotic | [Brand name]
Venofer (Luitpold). | [Clinical Use]
Phosphate binder | [Drug interactions]
Potentially hazardous interactions with other drugs
Antibacterials: reduced absorption of 4-quinolones
and tetracyclines.
Dimercaprol: avoid concomitant use.
Mycophenolate: may significantly reduce absorption
of mycophenolate. | [Metabolism]
After intravenous infusion, iron sucrose is taken up by
the cells of the reticuloendothelial cells, particularly in the
liver and spleen. The reticuloendothelial cells gradually
separate iron from the iron-sucrose complex. Most
absorbed iron is bound to transferrin and transported
to the bone marrow where it is incorporated into
haemoglobin; the remainder is contained within the
storage forms, ferritin or haemosiderin, or as myoglobin,
with smaller amounts occurring in haem-containing
enzymes or in plasma bound to transferrin.
Only very small amounts of iron are excreted as the
majority released after the destruction of the haemoglobin
molecule is re-used. |
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