ChemicalBook--->CAS DataBase List--->8047-67-4

8047-67-4

8047-67-4 Structure

8047-67-4 Structure
IdentificationMore
[Name]

Iron saccharate
[CAS]

8047-67-4
[Synonyms]

ferric hydroxide sucrose complex
FERRIC OXIDE, SACCHARATED
IRON (III) OXIDE, SACCHARATED
Iron saccharate
saccharated iron oxide
collironi.v.
feojectin
ferricsaccharate
ferricsaccharate...ironoxide(mix.)
ferrivenin
ironoxide,saccharated
ironsugar
iviron
neo-ferrum
proferrin
saccharatedferricoxide
saccharatediron
IronSucrose
Iron(III) saccharate
IRONSUCROSEUSP
[EINECS(EC#)]

232-464-7
[Molecular Formula]

C18H24Fe2O24
[MDL Number]

MFCD00166305
[Molecular Weight]

736.06
[MOL File]

8047-67-4.mol
Chemical PropertiesBack Directory
[Melting point ]

168-171°C
[storage temp. ]

Refrigerator
[solubility ]

Water (Slightly)
[form ]

Solid
[color ]

Brown to Dark Brown
[InChI]

InChI=1/3C6H10O8.2Fe/c3*7-1(3(9)5(11)12)2(8)4(10)6(13)14;;/h3*1-4,7-10H,(H,11,12)(H,13,14);;/q;;;2*+3/p-6/t3*1-,2-,3-,4+;;/s3
[InChIKey]

ADQSUDSYBZBMFT-JMMWHMDLNA-H
[CAS DataBase Reference]

8047-67-4(CAS DataBase Reference)
[IARC]

3 (Vol. 2, Sup 7) 1987
[EPA Substance Registry System]

8047-67-4(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501
[HS Code ]

29400090
[Toxicity]

LD50 in mice (mg Fe/kg): >2500 orally; >200 i.v. (Geisser)
Hazard InformationBack Directory
[Chemical Properties]

Brown solid
[Uses]

Iron Saccharate has been used to treat iron deficiency and iron deficiency anemia associated with different chronic diseases.
[Uses]

Semi-synthetic macrolide antibiotic
[Brand name]

Venofer (Luitpold).
[Clinical Use]

Phosphate binder
[Drug interactions]

Potentially hazardous interactions with other drugs
Antibacterials: reduced absorption of 4-quinolones and tetracyclines.
Dimercaprol: avoid concomitant use.
Mycophenolate: may significantly reduce absorption of mycophenolate.
[Metabolism]

After intravenous infusion, iron sucrose is taken up by the cells of the reticuloendothelial cells, particularly in the liver and spleen. The reticuloendothelial cells gradually separate iron from the iron-sucrose complex. Most absorbed iron is bound to transferrin and transported to the bone marrow where it is incorporated into haemoglobin; the remainder is contained within the storage forms, ferritin or haemosiderin, or as myoglobin, with smaller amounts occurring in haem-containing enzymes or in plasma bound to transferrin. Only very small amounts of iron are excreted as the majority released after the destruction of the haemoglobin molecule is re-used.
Spectrum DetailBack Directory
[Spectrum Detail]

Iron saccharate(8047-67-4)MS
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