| Identification | More | [Name]
3-(Dimethylamino)benzoic acid | [CAS]
99-64-9 | [Synonyms]
3-DIMETHYLAMINOBENZOIC ACID
M-DIMETHYLAMINOBENZOIC ACID
M-(N,N-DIMETHYLAMINO) BENZOIC ACID
3-(dimethylamino)-benzoicaci
Benzoicacid,3-(dimethylamino)-
3-Diaminomethylbenzoic acid
3-DIMETHYLAMINOBENZOIC ACID, CRYSTALLIZE D
3-DIMETHYLAMINO-BENZOESAEURE
3-(DIMETHYLAMINO)BENZOIC ACID 97%.
3-Dimethylaminobenzoic
META DIMETHYLAMINOBENZOIC ACID
M-dimetylaminobenzoic acid
3-(N,N-Dimethylamino)benzoic | [EINECS(EC#)]
202-775-2 | [Molecular Formula]
C9H11NO2 | [MDL Number]
MFCD00002497 | [Molecular Weight]
165.19 | [MOL File]
99-64-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Light yellow to yellow-beige crystalline powder | [Melting point ]
148-150 °C(lit.) | [Boiling point ]
293.03°C (rough estimate) | [density ]
1.1603 (rough estimate) | [refractive index ]
1.5200 (estimate) | [storage temp. ]
Store below +30°C. | [solubility ]
methanol: 50mg/mL, clear to very slightly hazy, yellow to brown | [form ]
Crystalline Powder | [pka]
3.36±0.10(Predicted) | [color ]
Light yellow to yellow-beige | [Water Solubility ]
Soluble in methanol (50 mg/ml). Insoluble in water. | [Detection Methods]
HPLC,NMR,T | [BRN ]
2208586 | [InChI]
InChI=1S/C9H11NO2/c1-10(2)8-5-3-4-7(6-8)9(11)12/h3-6H,1-2H3,(H,11,12) | [InChIKey]
NEGFNJRAUMCZMY-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC=CC(N(C)C)=C1 | [CAS DataBase Reference]
99-64-9(CAS DataBase Reference) | [EPA Substance Registry System]
99-64-9(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow to yellow-beige crystalline powder | [Uses]
3-(Dimethylamino)benzoic acid has been used to analyse glucose content from the extraction of starch and soluble sugars. | [Uses]
3-Dimethylaminobenzoic acid is used as a benzoic acid derivative. | [Biochem/physiol Actions]
3-dimethylaminobenzoic?acid?(DMAB)?can be used to quantity the activity of peroxidase and manganese peroxidase. | [Synthesis]
In a 250 mL three-neck flask, 95 mL of methanol and 3 mL of tetrahydrofuran were added, followed by 16.7 g of m-nitrobenzoic acid and 0.2 g of 5% palladium carbon catalyst. A constant pressure dropping funnel was installed and 15.2 mL of 37% formaldehyde aqueous solution was added to it. The air in the reaction system was replaced with hydrogen via an air pump. The reaction system was warmed up to 64 °C and the reaction was stirred at this temperature until hydrogen uptake stopped. Subsequently, the hydrogenation reaction was continued by slowly adding the formaldehyde solution through a dropping funnel until the hydrogen uptake stopped again. After stopping stirring, the reaction mixture was filtered to recover the catalyst. The filtrate was concentrated to precipitate the product m-dimethylaminobenzoic acid. The precipitate was collected by filtration, washed with a small amount of water and dried at 100 °C to give 15.3 g of m-dimethylaminobenzoic acid in 93% yield. The recovered catalyst was washed with reaction solvent and could be reused in subsequent reactions. | [References]
[1] Patent: CN107056633, 2017, A. Location in patent: Paragraph 0013; 0014; 0015; 0016
[2] Journal of the Chemical Society, 1950, p. 1342,1345 |
|
|