ML324
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- CAS号:
- 1222800-79-4
- 英文名:
- ML234
- 英文别名:
- ML243;ML324;ML234;CS-2198;ML324, ML-324;5-Pyrroledione;ML234 USP/EP/BP;NCGC00183808-01;ML-324;ML324;ML 324;ML324(CID-44143209)
- 中文名:
- ML324
- 中文别名:
- 优选]ML324;ML324,JMJD2抑制剂;JMJD2去甲基酶抑制剂(ML324);N-(3-(二甲胺基)丙基)-4-(8-羟基喹啉-6-基)苯甲酰胺;N-(3-(二甲氨基)丙基)-4-(8-羟基喹啉-6-基)苯甲酰胺
- CBNumber:
- CB72744613
- 分子式:
- C21H23N3O2
- 分子量:
- 349.43
- MOL File:
- 1222800-79-4.mol
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ML324化学性质
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熔点:
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>187oC (dec.)
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沸点:
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590.1±50.0 °C(Predicted)
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密度:
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1.188±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,2-8°C
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溶解度:
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DMSO: soluble10mg/mL, clear
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酸度系数(pKa):
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4.71±0.40(Predicted)
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形态:
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powder
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颜色:
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white to light brown
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稳定性:
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Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
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ML324性质、用途与生产工艺
ML324是一种选择性的jumonji histone demethylase (JMJD2)抑制剂， 其对JMJD2E的IC50为920 nM。
ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes. ML324 demonstrates potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection by inhibiting viral IE gene expression.
In a mouse ganglia explant model of latently infected mice, ML324 suppresses the formation of HSV plaques, and blocks HSV-1 reactivation.
ML324
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-12725 | ML324 | | 5 mg | 487元 |
| 2024/01/25 | HY-12725 | ML324
ML324 | 1222800-79-4 | 10mg | 780元 |
1222800-79-4, ML324 相关搜索:
- Inhibitors
- 抗疟配体
- 生物试剂
- 细胞生物学试剂
- 抑制剂
- 小分子抑制剂，天然产物
- ML324,JMJD2抑制剂
- 优选]ML324
- N-(3-(二甲胺基)丙基)-4-(8-羟基喹啉-6-基)苯甲酰胺
- JMJD2去甲基酶抑制剂(ML324)
- N-(3-(二甲氨基)丙基)-4-(8-羟基喹啉-6-基)苯甲酰胺
- 1222800-79-4
- ML324, ML-324
- ML243
- 5-Pyrroledione
- ML234 USP/EP/BP
- Benzamide, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-
- ML-324;ML324;ML 324
- CS-2198
- ML324(CID-44143209)
- NCGC00183808-01
- N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide
- ML324
- ML234