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GABEXATE

GABEXATE Struktur
39492-01-8
CAS-Nr.
39492-01-8
Englisch Name:
GABEXATE
Synonyma:
GABEXATE;Gabexate USP/EP/BP;GabexateMesylateBase;4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester;ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium;4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester;Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester;[N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate
CBNumber:
CB1258637
Summenformel:
C16H23N3O4
Molgewicht:
321.37
MOL-Datei:
39492-01-8.mol
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GABEXATE Eigenschaften

Siedepunkt:
472.2±55.0 °C(Predicted)
Dichte
1.20±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.83±0.70(Predicted)
Farbe
White

Sicherheit

GABEXATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Gabexate mesylate is used in combination with somatostatin and octreotide in the treatment of severe acute pancreatitis in elderly patients.

Biologische Aktivität

Serine protease inhibitor; inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC 50 values are 9.4, 30, 41 and 110 mM respectively). Antithrombotic in vitro and in vivo . Also inhibits LPS-induced TNF- α production, probably by inhibiting NF- κ B and AP-1 activation.

GABEXATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Natriumhydroxid Ethylbenzoat Thionyldichlorid Pyridin

Downstream Produkte

GABEXATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 32)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd 		18192627656
 1012@dideu.com China 3422 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167
 1026@dideu.com China 9320 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 29220 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118
 xie@china-sinoway.com China 992 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49739 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
9ding chemical ( Shanghai) Limited 4009209199
sales@9dingchem.com China 18216 56
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60

39492-01-8()Verwandte Suche:

4-Butoxybenzoesure 6-Guanidinohexansure
  • GABEXATE
  • GabexateMesylateBase
  • [N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate
  • 4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester
  • 4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester
  • diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium
  • Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester
  • Gabexate USP/EP/BP
  • ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate
  • 39492-01-8
  • Proteinase-activated receptor (PAR)
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