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N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Produkt Beschreibung

FENFLURAMINE Struktur
458-24-2
CAS-Nr.
458-24-2
Bezeichnung:
N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin
Englisch Name:
FENFLURAMINE
Synonyma:
Acino;Pesos;S-768;C06996;EQUINE;Obedrex;Adipomin;Ponderex;Pondimin;Rotondin
CBNumber:
CB1325500
Summenformel:
C12H16F3N
Molgewicht:
231.26
MOL-Datei:
458-24-2.mol

N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Eigenschaften

Schmelzpunkt:
170°C
Siedepunkt:
bp12 108-112°
Dichte
1.0950 (estimate)
storage temp. 
?20°C
pka
pKa 9.10 (Uncertain)

Sicherheit

Kennzeichnung gefährlicher F,T
R-Sätze: 11-23/24/25-39/23/24/25
S-Sätze: 16-36/37-45
Toxizität LD50 i.p. in mice: 144 mg/kg

N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anorexic.

Definition

ChEBI: A secondary amino compound that is 1-phenyl-propan-2-amine in which one of the meta-hydrogens is substituted by trifluoromethyl, and one of the hydrogens attached to the nitrogen is substituted by an ethyl group. It binds to the serotonin reu take pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding ehavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine was used as the hydrochloride for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertensio .

Trademarks

Pondimin (Robins).

Weltgesundheitsorganisation (WHO)

Fenfluramine, dexfenfluramine and phentermine were approved individually more than 20 years ago in the USA for single-drug, short-term treatment of obesity. The manufacturers of fenfluramine and dexfenfluramine have since voluntarily withdrawn both products from the market worldwide. Phentermine remains available.

N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 0)Lieferanten
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458-24-2(N-Ethyl-alpha-methyl-3-(trifluor-methyl)benzolethanamin)Verwandte Suche:


  • FENFLURAMINE
  • AURORA KA-7683
  • AURORA KA-7684
  • 1-(meta-Trifluoromethyl-phenyl)-2 ethylaminopropane
  • 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
  • Acino
  • Adipomin
  • N-Ethyl-1-[3-(trifluoromethyl)phenyl]-2-propanamine
  • N-Ethyl-alpha-methyl-3-trifluoromethylphenethylamine
  • Obedrex
  • Pesos
  • Phenethylamine, N-ethyl-alpha-methyl-m-(trifluoromethyl)-
  • Ponderax PA
  • Ponderex
  • Pondimin
  • Rotondin
  • ethyl(alpha-methyl-3-trifluoromethylphenethyl)amine
  • Phenfluoramine
  • n-ethyl-alpha-methyl-m-(trifluoromethyl)-phenethylamin
  • n-ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine
  • FENCLORIN
  • N-Ethyl-α-methyl-3-(tfifluoromethyl)benzeneethanamine
  • Ponderal:Pon-derax
  • S-768
  • Fenfluramin
  • N-Ethyl-3-trifluoromethyl-α-methylbenzeneethanamine
  • N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine
  • N-Ethyl-α-methyl-m-(trifluoromethyl)benzeneethanamine
  • dl-Fenfluramine
  • C06996
  • Methanol(Test Fenfluramine, 1.0 mg/mL)
  • FenfluraMine API
  • EQUINE
  • Fenfluramine solution
  • 458-24-2
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