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Clindamycinhydrochlorid Produkt Beschreibung

Clindamycin hydrochloride Struktur
21462-39-5
CAS-Nr.
21462-39-5
Bezeichnung:
Clindamycinhydrochlorid
Englisch Name:
Clindamycin hydrochloride
Synonyma:
CLEOCIN;Dalacin;U-21251F;dalacina;Dalacin S;Lujiemycin;Clidamacin;Panancocin;CLINDAMYCIN HC;ClindaMycin-d3
CBNumber:
CB2398837
Summenformel:
C18H34Cl2N2O5S
Molgewicht:
461.44
MOL-Datei:
21462-39-5.mol

Clindamycinhydrochlorid Eigenschaften

Schmelzpunkt:
141°C
storage temp. 
2-8°C
Löslichkeit
H2O: 50 mg/mL, clear, colorless
Aggregatzustand
neat
BRN 
4070786
InChIKey
AUODDLQVRAJAJM-XJQDNNTCSA-N
CAS Datenbank
21462-39-5(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 26-36-37/39
WGK Germany  2
RTECS-Nr. GF2275000
10
HS Code  29419000

Clindamycinhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

White Solid

Verwenden

antibacterial, inhibits protein synthesis

Verwenden

Clindamycin hydrochloride is a salt of clindamycin, a semi-synthetic lincosamide. The hydrochloride salt forms at the basic N-ethylproline moiety and is the preferred pharmaceutical formulation. Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin hydrochloride acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin hydrochloride has been extensively studied with over 8,000 literature citations.

Verwenden

Labelled Clindamycin. Semi-synthetic antibiotic prepared from Lincomycin;Labeled Clindamycin, intended for use as an internal standard for the quantification of Clindamycin by GC- or LC-mass spectrometry.

Trademarks

Cleocin (Pharmacia & Upjohn).

Kontakt-Allergie

This lincosanide antibiotic is used in topical form for acne, or systemically has been responsible for exanthematous rashes and acute generalized exanthematous pustulosis.

Clinical Use

Clindamycin is recommended for the treatment of a widevariety of upper respiratory, skin, and tissue infections causedby susceptible bacteria. Its activity against streptococci,staphylococci, and pneumococci is indisputably high, and it isone of the most potent agents available against somenon–spore-forming anaerobic bacteria, the Bacteroides spp.in particular. An increasing number of reports of clindamycin-associated GI toxicity, which range in severity fromdiarrhea to an occasionally serious pseudomembranous colitis,have, however, caused some clinical experts to call for areappraisal of the role of this antibiotic in therapy.Clindamycin- (or lincomycin)-associated colitis may be particularlydangerous in elderly or debilitated patients and hascaused deaths in such individuals. The colitis, which is usuallyreversible when the drug is discontinued, is now believedto result from an overgrowth of a clindamycin-resistant strainof the anaerobic intestinal bacterium Clostridium difficile.229The intestinal lining is damaged by a glycoprotein endotoxinreleased by lysis of this organism.
The glycopeptide antibiotic vancomycin has been effectivein the treatment of clindamycin-induced pseudomembranouscolitis and in the control of the experimentally induced bacterial condition in animals. Clindamycin shouldbe reserved for staphylococcal tissue infections, such as cellulitisand osteomyelitis, in penicillin-allergic patients andfor severe anaerobic infections outside the central nervoussystem. Ordinarily, it should not be used to treat upper respiratorytract infections caused by bacteria sensitive to othersafer antibiotics or in prophylaxis.

Veterinary Drugs and Treatments

Clindamycin products are approved for use in dogs and cats. The labeled indications for dogs include wounds, abscesses and osteomyelitis caused by Staphylococcus aureus. Because clindamycin has excellent activity against most pathogenic anaerobic organisms, it is also used extensively for those infections. Clindamycin is used for a variety of protozoal infections, including toxoplasmosis. For further information, refer to the Dosage or Pharmacology sections.

Clindamycinhydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Clindamycinhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 332)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22631 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3015 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 569 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1892 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30053 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23978 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28235 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12231 58

21462-39-5(Clindamycinhydrochlorid)Verwandte Suche:


  • Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride
  • (4R)-N-[(1S,2S)-2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylthio)-2-oxanyl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide hydrochloride
  • Lujiemycin
  • monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio
  • CLINDAMYCIN HC
  • Clindaymcin Hydrochloride BP98,USP25,EP97
  • L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride
  • CLINDAMYCINHYDROCHLORIDE,CRYSTAL
  • CLINDAMYCINHYDROCHLORIDE,USP
  • CLINDAMYCIN HCI
  • (7S)-7CHLORO-7-DEOXYLINCOMYCIN HCL
  • Clindamycin hydrochloride, Antibiotic for Culture Media Use Only
  • Clindamycin IMP
  • CLINDAMYCIN HYDROCHLORIDE, LINCOSAMI
  • Clindamycin hydrochloride, nonsterileUSP, ≥ 860 μg/mg
  • (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2- pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside Hydrochloride
  • Clindamycin hydrochloride Solution, 1000ppm
  • Clindamycin Impurity 14(Clindamycin Phosphate EP Impurity E)
  • (2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE
  • (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE
  • 7(S)-CHLORO-7-DEOXYLINCOMYCIN
  • 7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL
  • 7[S]-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE
  • CLEOCIN
  • CLEOCIN HYDROCHLORIDE
  • CLINDAMYCIN HCL
  • CLINDAMYCIN HYDROCHLORIDE
  • U-21251F
  • 7-chloro-7-deoxylincomycinhydrochloride
  • clindimycinhydrochloride
  • clindomycinhydrochloride
  • dalacina
  • Clindamycin hydrochloride, nonsterile
  • Clidamacin
  • Dalacin
  • Dalacin S
  • Panancocin
  • (2S-trans)-Methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octothiopyranoside monohydrochloride
  • (7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin
  • Clindamycin Base & Phosphate
  • Clindamycin hydrochloride,(7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin
  • (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2- pyrrolidinyl]carbonyl]aMino]-1-thio-
  • ClindaMycin hydrochloride Antipyrotic
  • ClindaMycin HCL USP30 EP5 BP2007
  • ClindaMycin-d3
  • 7-Chloro-7-deoxylincoMycin hydrochloride, 7-ChlorolincoMycin hydrochloride
  • (L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1))
  • 21462-39-5
  • 21642-39-5
  • C18H33ClN2O5SClH
  • C18H34Cl2N2O5S
  • C18H33ClN2O5SHClC18H34Cl2N2O5S
  • C18H33CIN2O5SHCL
  • C18H33ClN2O5SxHCl
  • C18Cl1H33N2O5S1
  • C18H30D3ClN2O5S
  • Antibiotics
  • Antibiotics A to Z
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