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9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol Produkt Beschreibung

Vitamin D2 Struktur
50-14-6
CAS-Nr.
50-14-6
Bezeichnung:
9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
Englisch Name:
Vitamin D2
Synonyma:
Daral;Vio-D;Doral;Buco-D;Condol;Crtron;Decaps;minad2;Arthin;Ertron
CBNumber:
CB3731934
Summenformel:
C28H44O
Molgewicht:
396.65
MOL-Datei:
50-14-6.mol

9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol Eigenschaften

Schmelzpunkt:
114-118 °C(lit.)
alpha 
82 º (c=3, in acetone 25 ºC)
Siedepunkt:
460.3°C (rough estimate)
Dichte
0.9784 (rough estimate)
Dampfdruck
7 x l0-7 Pa (20 °C), est.)
Brechungsindex
1.5100 (estimate)
Flammpunkt:
14 °C
storage temp. 
2-8°C
Löslichkeit
H2O: 200 mg/mL, clear to hazy
Aggregatzustand
powder
Farbe
white to yellowish
Optische Aktivität
[α]20/D +105±2°, c = 4% in ethanol
Wasserlöslichkeit
Soluble in ethanol, water, methanol, dimethylformamide, and dimethyl sulfoxide.
Merck 
14,10018
BRN 
1916682
InChIKey
MECHNRXZTMCUDQ-RKHKHRCZSA-N
CAS Datenbank
50-14-6(CAS DataBase Reference)
NIST chemische Informationen
Ergocalciferol(50-14-6)
EPA chemische Informationen
9,10-Secoergosta- 5,7,10(19),22-tetraen-3-ol, (3.beta.,5Z,7E,22E)-(50-14-6)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn,T+,T,F
R-Sätze: 22-48/25-26-24/25-40-23/24/25-48/22-23-11-20
S-Sätze: 28-36/37-45-28A-36-26-36/37/39-22-16-7
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS-Nr. KE1050000
1-8-10
TSCA  Yes
HazardClass  6.1(a)
PackingGroup  II
HS Code  29362900
Giftige Stoffe Daten 50-14-6(Hazardous Substances Data)
Bildanzeige (GHS)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H300 Lebensgefahr bei Verschlucken. Akute Toxizität oral Kategorie 2 Achtung P264, P270, P301+P310, P321, P330,P405, P501
H301 Giftig bei Verschlucken. Akute Toxizität oral Kategorie 3 Achtung P264, P270, P301+P310, P321, P330,P405, P501
H311 Giftig bei Hautkontakt. Akute Toxizität dermal Kategorie 3 Achtung P280, P302+P352, P312, P322, P361,P363, P405, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H330 Lebensgefahr bei Einatmen. Akute Toxizität inhalativ Kategorie 1 Achtung P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H372 Schädigt bei Hautkontakt und Verschlucken die Organe bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 1 Achtung P260, P264, P270, P314, P501
H373 Kann die Organe schädigen bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P260 Dampf/Aerosol/Nebel nicht einatmen.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P320 Besondere Behandlung dringend erforderlich
P330 Mund ausspülen.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.
R48/25:Giftig: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Verschlucken.
R26:Sehr giftig beim Einatmen.
R24/25:Giftig bei Berührung mit der Haut und beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.

Chemische Eigenschaften

Ergocalciferol is an odorless white crystalline solid

Verwenden

The synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. Commercial solutions are usually made with propylene glycol or sesame oil. Antirachitic

Verwenden

antirachitic vitamin; LD50 (rat) 56 mg/kg po

Verwenden

Rodenticide.

Verwenden

Vitamin d2 is fat-soluble, and is stable unless oxidized. It is necessary for growth and maintenance of teeth and bones and the normal utilization of calcium and phosphorus; it is used medicinally in the treatment of rickets and as a dietary supplement. Its sources include fish liver and vitamin d-fortified milk.

Verwenden

Vitamin D2 is formed by photochemical cleavage of ergosterin, which is a side-product of many fermentation processes. Microorganisms usually contain up to 3 percent of ergosterin.

Definition

ChEBI: A vitamin D supplement and has been isolated from alfalfa.

Trademarks

Deltalin (Lilly); Drisdol(Sanofi Aventis).

Allgemeine Beschreibung

Odorless white crystals. Used as a dietary supplement and food additive.

Reaktivität anzeigen

Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Health Hazard

Vitamin D2 poisoning disturbs calcium metabolism and causes kidney damage. Vitamin D2 in a single acute ingestion presents no toxic hazards. Daily ingestion in excess of 5000 units/day in children or 7500 units/day in adults will produce toxic symptoms associated with hypervitaminosis D. Those with hypercalcemia are at a greater risk.

Brandgefahr

Shows signs of decomposition when stored for a few days at room temperature.

Sicherheitsprofil

Poison by ingestion, intraperitoneal, intravenous, and intramuscular routes. An experimental teratogen. Human systemic effects by ingestion: anorexia, nausea or vomiting, and weight loss. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.

mögliche Exposition

Used as a nutrient and/or dietary supplement food additive

Stoffwechselwegen

Ergocalciferol (vitamin D2) is a product made by the UV irradiation of yeast ergosterol. It is a common form of vitamin D and it has very similar biological activity to that of cholecalciferol (vitamin D3) in the treatment of the vitamin D deficiency diseases (e.g. rickets). The bioactive form of this vitamin is also the 1,25-dihydroxy-derivative and this has equal antirachitic activity to that of the cholecalciferol analogue (Jones et al., 1975).

Versand/Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials

läuterung methode

It is converted into its 3,5-dinitrobenzoyl ester and crystallised repeatedly from acetone. The ester is then saponified and the free vitamin is isolated. [Laughland & Phillips Anal Chem 28 817 1956, Beilstein 6 IV 4404.]

Degradation

It is unstable in light and air and in acidic media. It is inactivated within a few days under normal exposure conditions. This is due to oxidation and fragmentation of the triene functionality. Ergocalciferol is slightly more unstable, probably because of the additional alkene group in the side chain. One of the several degradation products of ergocalciferol has been identified as the ketone (8, shown in Scheme 1) formed by the loss of the methano-cyclohexanol function (Stewart et al., 1984).

Inkompatibilitäten

Dust may be combustible and may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides.

Waste disposal

Dispose of contents and container to an approved waste disposal plant. All federal, state, and local environmental regulations must be observed. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffeegrounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 327)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
CARBOGEN AMCIS B.V.
+31 318 545 767
+31 318 54 57 67 rene.vanoosten@carbogen-amcis.com THE NETHERLANDS 10 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 535 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 892 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58

50-14-6(9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol)Verwandte Suche:


  • Oleovitamin D2
  • Ergocalciferol for system suitability
  • Ergocalciferol, Vitamin D2, Calciferol
  • Calciferol[Ergocalciferol]
  • 9,10-secoergosta-5,7,10(19),22-tetra-en-3-ol
  • 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-
  • activatedergosterol
  • Buco-D
  • Calciferol (vitamin D2)
  • Calciferon 2
  • calciferon2
  • component of Geltabs Vitamin D
  • component of Haliver
  • Condacaps
  • Condocaps
  • Condol
  • Crtron
  • Crystallina
  • Daral
  • D-Arthin
  • Davitamon D
  • davitamond
  • Davitin
  • Decaps
  • Dee-Osterol
  • Dee-Ron
  • Dee-Ronal
  • Dee-Roual
  • Deltalin
  • minad2
  • Mulsiferol
  • Novovitamin-D
  • Oleovitamin D
  • Oleovitamin D, Synthetic
  • oleovitamind
  • Ostelin
  • Radiostol
  • Radstein
  • Radsterin
  • Rodine C
  • rodinec
  • Shock-ferol
  • Shock-ferol sterogyl
  • sorexc.r.
  • Sterogyl
  • Synthetic Vitamin D
  • Uvesterol-D
  • Vigantol
  • Vio-D
  • Viostdrol
  • Viosterol in Oil
  • Vitavel-D
  • ERGOCALCIFEROL-WATER SOLUBLE
  • ERGOSTEROL IRRADIATED
  • 'ERGOSTEROL IRRADIATED'
  • 9,10-secoergosta-5,7,10,22-tetraen-3-ol
  • 5,7,10(19),22-CHOLESTATETRAEN-24BETA-METHYL-3BETA-OL-9,10-SECO
  • 5,7,10(19),22-CHOLESTATETRAEN-24B-METHYL-3B-OL-9,10-SECO
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