Ceramides

Ceramides Struktur
100403-19-8
CAS-Nr.
100403-19-8
Englisch Name:
Ceramides
Synonyma:
CERAMIDE 3;CERAMIDE 2;CERAMIDE 1;Ceramides NP;CERAMIDE 6 II;CERAMIDE 5;CeramideNP;Aqua Ceramide;Ceramide 3B;Ceramide W.S
CBNumber:
CB4874731
Summenformel:
C24H47NO3
Molgewicht:
397.63488
MOL-Datei:
100403-19-8.mol

Ceramides Eigenschaften

storage temp. 
Store at -20°C
Löslichkeit
Methanol: 25 mg/mL
Aggregatzustand
A crystalline solid
LogP
13.577 (est)
CAS Datenbank
100403-19-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Ceramides Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The ceramides mixture consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.

Verwenden

ceramides is a family of naturally occurring lipids that act primarily in the skin’s uppermost layer, forming a protective barrier and reducing natural transepidermal water loss. Ceramides repair the stratum corneum layer in cases of dry skin, improve skin hydration, and increase the feeling of softness. They are beneficial for stressed, sensitive, scaly, rough, dry, aged, and sun-damaged skin. Ceramides play an essential role in the structure of superficial epidermal layers and form an integral part of the intercellular membrane network. They help generate and sustain the skin’s barrier function. This is extremely important: if the stratum corneum’s hydration is maintained, then it functions more normally in terms of flexibility and desquamation, its integrity is upheld, and the skin is less susceptible to irritation. Ceramide production decreases with age, accentuating any tendency to dry skin. When incorporated into a skin care preparation, the topical application of ceramides could benefit the stratum corneum if the ceramides manage to fill the intercellular spaces and if they are hydrolyzed by the correct extracellular enzymes on the skin. Such application also can stimulate ceramide production in the skin, thereby increasing the skin’s natural lipid content and reinforcing the skin’s protective barrier, measured through transepidermal water loss. Topically applied ceramides have been shown to capture and bind water, necessary for the skin to remain supple, smooth, and hydrated. natural ceramides are obtained from animals and plants. While ceramides can be synthetically manufactured, it is hard to obtain an identical equivalent to those found in nature, making them expensive raw materials.

Mechanism of action

Ceramides, fatty acid and cholesterol constitute the extracellular lipid matrix of epidermal barrier in an approximately equimolar ratio and are assembled in a dense orthorhombic lateral packing within SC interstices. Among them, ceramides are central to the permeability barrier structure and function. Epidermal ceramides account for approximately 50 % of total epidermal lipid by weight. In addition, ceramides also act as an active second messenger, regulate keratinocyte proliferation and differentiation, enhance proinflammatory cytokines production, and modulate immune responses. Aberrant metabolism and function of ceramides is involved in the pathogenesis of several inflammatory skin diseases, including psoriasis, atopic dermatitis (AD) and ichthyosis[1-2].

Ceramides Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Ceramides Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 278)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+86-18580541567 +86-17782035140
sales@zhswyy.com China 338 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 992 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953
sales@pioneerbiotech.com China 3000 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126
info@binbobiological.com China 282 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5993 58
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410
sales@ichemie.com China 985 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 1000 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823
admin@guyunchem.com China 616 58
Wuhan Quanjinci New Material Co.,Ltd.
+8615271838296
kyra@quanjinci.com China 1532 58

100403-19-8()Verwandte Suche:


  • CERAMIDE 4
  • CERAMIDE 1 A
  • HYDROXYCAPROYL PHYTOSPHINGOSINE
  • HYDROXYCAPRYLOYL PHYTOSPHINGOSINE
  • HYDROXYLAUROYL PHYTOSPHINGOSINE
  • LACTOYL PHYTOSPHINGOSINE
  • PHYTOSPHINGOSINE LACTATE
  • Ceramides
  • PHYTOSPHINGOSINE PCA
  • BioaActive Ceramide
  • BioaActive Repair
  • Nanoactive Ceramide
  • Soluble Ceramide
  • SymRepair 100
  • ProductName:Ceramide-2(highcontents)
  • Nano-Liposomal Ceramide
  • Ceramide Liposome
  • Ceramdie
  • Ceramides2
  • Ceramides ISO 9001:2015 REACH
  • Ceramide 3% (rice bran)
  • CAPROYL SPHINGOSINE
  • CERAMIDE 1
  • CERAMIDE 2
  • CERAMIDE 3
  • CERAMIDE 5
  • CERAMIDE 6 II
  • Einecs 309-560-3
  • Aqua Ceramide
  • Ceramides Mixture
  • Ceramide W.S
  • Ceramide Powder
  • CeramideNP
  • Ceramides NP
  • Ceramide 3B
  • Ceramide IIIB
  • CERAMIDE NP2
  • Ceramide NP1
  • Ceramide VI(AP)
  • Ceramide IIIB(NP1)
  • Ceramide NP1(IIIB)
  • Ceratamine
  • Oil soluble ceramide NP transparent oil
  • NP water-soluble dispersion particles
  • CERAMIDE AS
  • 100403-19-8
  • API
  • 100403-19-8
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