Ceftazidim
|
|
|
- CAS-Nr.
- 72558-82-8
- Bezeichnung:
- Ceftazidim
- Englisch Name:
- CeftazidiMe
- Synonyma:
- hy;CEFTAZIDINE;CeftazidiMe with SodiuM Carbonate;Tazidime;Ceptaz;Fortaz;Ceftazidime CRS;caz;sn401;C06889
- CBNumber:
- CB7289569
- Summenformel:
- C22H22N6O7S2
- Molgewicht:
- 546.57
- MOL-Datei:
- 72558-82-8.mol
|
Ceftazidim Eigenschaften
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Löslichkeit
- ≥21.25 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
- Aggregatzustand
- powder to crystal
- Farbe
- White to Orange to Green
- Merck
- 14,1946
- Stabilität:
- Stable, but keep refrigerated. Incompatible with strong oxidizing agents, nitric acid, permanganates, peroxides.
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P261, P285, P304+P341, P342+P311,P501 |
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht außerhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P284 |
Atemschutz tragen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
Ceftazidim Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
In ceftazidime the oxime moiety is more complex, containing two methyl groups and a carboxylic acid. This
assemblage conveys even more pronounced β-lactamase stability, greater anti–Pseudomonas aerugi nosa,
and increased activity against Gram-positive organisms. The C-3 side chain has been replaced by a charged
pyridinium moiety. The latter considerably enhances water solubility and also highly activates the β-lactam
bond toward cleavage. The drug must be protected against heat and light and may darken without significant
loss of potency. It is not stable under some conditions. such as the presence of aminoglycosides and
vancomycin. It also is attacked readily in sodium bicarbonate solutions. Resistance is mediated by
chromosomally mediated β-lactamases and by lack of penetration into target bacteria. Otherwise, it has a
very broad antibacterial spectrum.
Chemische Eigenschaften
solid
Verwenden
Like most of the third-generation cephalosporin antibiotics described above, ceftazidime
has a broad spectrum of antimicrobial action, including the most clinically important
microorganisms: Gram-positive, Gram-negative, aerobic, and anaerobic. It is resistant to
most beta-lactamases of Gram-positive and Gram-negative bacteria.
It is used for treating most serious bacterial infections. Synonyms of this drug are fortum, ceftim, stacef, and tazicef.
Definition
ChEBI: A cephalosporin bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.
Ceftazidim Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ceftazidim Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 398)Lieferanten
72558-82-8(Ceftazidim)Verwandte Suche:
5-Thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsure, 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, Dinatriumsalz, [6R-[6α,7β(Z)]]-
(6R-trans)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsure
2-Acetamidoacrylsure
Ceftazidim
Cefazolin
[6R-[6α,7β(R*)]]-Hydrogen-4-carbamoyl-1-[[2-carboxylato-8-oxo-7-(phenylsulfonatoacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium, Mononatriumsalz
Cefaloridin
[[(1-Methylethyliden)amino]oxy]essigsure
- CeftazidimePentahydrateBufferedUsp24
- CEFTAZIDIME HYDRATE
- 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino] acetyl]
- 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium Inner Salt
- Fortam
- [(6R-[6α，7β(Z)]]-1-[[7-[[(2-Amino-4-thiazolyl)[(1-earboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabieyelo[4.2.0]oct-2-en-3-y1]methyl]pyridinium inner salt
- (6R,7R)-7-[(3Z)-3-(2-AMINO-1,3-THIAZOL-4-YL)-3-{[(2-CARBOXY-2-PROPANYL)OXY]IMINO}-2-OXOPROPYL]-8-OXO-3-(1-PYRIDINIUMYLMETHYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLATE
- (6R,7R)-7-[[(Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- (6R,7R)-7-[2-(2-Amino-4-thiazolyl)-2-[(Z)-1-carboxy-1-methylethoxyimino]acetylamino]-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
- Ceftazidime (contains ca. 10% Na2CO3)
- C06889
- CeftazidiMe (C22H22N6O7S2 · xH2O)
- Ceftim，Fortam
- Glazidim
- Kefadim
- Kefamin
- Panzid
- Stareef
- Tazicef：CAZ
- 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino] acetyl] amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-en-3-yl]methyl]pyridinum hydroxide inner
- Ceftazidime/Sodium Carbonate
- Ceftazidime
- caz
- Fortum
- gr20263
- innersalt,(6r-(6-alpha,7-beta-(z)))-droxid
- pyridinium,1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acety
- sn401
- 1-[[(6r,7r)-7-[[(2z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino] acetyl] amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-en-3-yl]methyl]pyridinum hydroxide inner salt
- thermogra
- (6R,7R)-7-[(Z)-2-(Aminothiazol-4-yl)-2-(2-carboxypropoxyimino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate
- Biotum
- Ceftacidin
- Modacin
- Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
- Pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, [6R-[6α,7β(Z)]]-
- Tazicef
- TIANFUCHEM--72558-82-8--High purity Ceptaz factory price
- Ceftazidime D6
- CeftazidimeQ: What is
Ceftazidime Q: What is the CAS Number of
Ceftazidime Q: What is the storage condition of
Ceftazidime
- Ceftazidime (GR20263)
- CEFTAZIDIME FREE ACID
- (6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (contains ca. 10% Na2CO3)
- (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- Ceftazidime powder
- Ceftazidime(containsca.10%Na2CO3)>
- Ceftazidime for peak identification CRS
- ceftazidime / Ceftazidime powder
- (6R,7R,z)-7-(2-(2-Aminothiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)-acetamido)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylatesodium
- (6R,7R)-7-((Z)-2
- Nitrazepam Solution, 100ppm
- Tazidime
- CEFTAZIDINE
- CeftazidiMe with SodiuM Carbonate
- Ceptaz
- hy
- Fortaz
- Ceftazidime CRS
