Saccharose

Sucrose Struktur
57-50-1
CAS-Nr.
57-50-1
Bezeichnung:
Saccharose
Englisch Name:
Sucrose
Synonyma:
SUGAR;SACCHAROSE;CANE SUGAR;Granulated sugar;White sugar;(2R,3R,4S,5S,6R)-2-(((2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxyMethyl)tetrahydrofuran-2-yl)oxy)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol;SACCHARUM;BEET SUGAR;Sucrose BP;Table sugar
CBNumber:
CB4337508
Summenformel:
C12H22O11
Molgewicht:
342.3
MOL-Datei:
57-50-1.mol

Saccharose Eigenschaften

Schmelzpunkt:
185-187 °C (lit.)
alpha 
67 º (c=26, in water 25 ºC)
Siedepunkt:
397.76°C (rough estimate)
Dichte
1.5805
Brechungsindex
66.5 ° (C=26, H2O)
Flammpunkt:
93.3°C
storage temp. 
Inert atmosphere,Room Temperature
Löslichkeit
H2O: 500 mg/mL
Aggregatzustand
Liquid
pka
12.7(at 25℃)
Farbe
White
Geruch (Odor)
Odorless
Säure-Base-Indikators(pH-Indikatoren)
5.5 - 7 at 342 g/l at 25 °C
PH
5.0-7.0 (25℃, 1M in H2O)
Optische Aktivität
[α]25/D +66.3 to +66.8°(lit.)
Wasserlöslichkeit
1970 g/L (15 ºC)
maximale Wellenlänge (λmax)
λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.08
Merck 
14,8881
BRN 
90825
Dielectric constant
3.3(Ambient)
Expositionsgrenzwerte
ACGIH: TWA 10 mg/m3
OSHA: TWA 15 mg/m3; TWA 5 mg/m3
NIOSH: TWA 10 mg/m3; TWA 5 mg/m3
Stabilität:
Stable. Combustible. Incompatible with strong oxidizing agents. Hydrolyzed by dilute acids and by invertase.
InChIKey
CZMRCDWAGMRECN-UGDNZRGBSA-N
LogP
-4.492 (est)
CAS Datenbank
57-50-1(CAS DataBase Reference)
NIST chemische Informationen
Sucrose(57-50-1)
EPA chemische Informationen
Sucrose (57-50-1)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 24/25-37/39-26
WGK Germany  2
RTECS-Nr. WN6500000
3
TSCA  Yes
HS Code  17019910
Giftige Stoffe Daten 57-50-1(Hazardous Substances Data)
Toxizität LD50 orally in Rabbit: 29700 mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten Räumen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Saccharose Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

WEISSER FESTSTOFF IN VERSCHIEDENEN FORMEN.

PHYSIKALISCHE GEFAHREN

Staubexplosion der pulverisierten oder granulierten Substanz in Gemischen mit Luft möglich.

CHEMISCHE GEFAHREN

Reagiert mit starken Oxidationsmitteln unter Feuergefahr.

ARBEITSPLATZGRENZWERTE

TLV: 10 mg/m?(als TWA); Krebskategorie A4 (nicht klassifizierbar als krebserzeugend für den Menschen); (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).

AUFNAHMEWEGE

Aufnahme in den Körper durch Inhalation und durch Verschlucken.

WIRKUNGEN BEI KURZZEITEXPOSITION

WIRKUNGEN BEI KURZZEITEXPOSITION:
Reizt möglicherweise mechanisch.

WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION

Möglich sind Auswirkungen auf die Zähne. Führt zu Zahnkaries. Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen.

LECKAGE

Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern.

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

Sucrose is a sugar obtained from sugar cane (Saccharum officinarum Linne' (Fam. Gramineae)), sugar beet (Beta vulgaris Linne' (Fam. Chenopodiaceae)), and other sources. It contains no added substances. Sucrose occurs as colorless crystals, as crystalline masses or blocks, or as a white crystalline powder; it is odorless and has a sweet taste.

Verwenden

sucrose (table sugar) is an emollient, mild emulsifier, and humectant. It can be used in place of glycerin.

Definition

ChEBI: Sucrose is a disaccharide formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose.

Vorbereitung Methode

Sucrose is obtained from the sugar cane plant, which contains 15–20% sucrose, and sugar beet, which contains 10–17% sucrose. Juice from these sources is heated to coagulate water-soluble proteins, which are removed by skimming. The resultant solution is then decolorized with an ion-exchange resin or charcoal and concentrated. Upon cooling, sucrose crystallizes out. The remaining solution is concentrated again and yields more sucrose, brown sugar, and molasses.

Allgemeine Beschreibung

White odorless crystalline or powdery solid. Denser than water.

Air & Water Reaktionen

Water soluble. Sugar dust explosion is possibility.

Reaktivität anzeigen

D(+)-Sucrose is a reducing agent. Can react explosively with oxidizing agents such as chlorates and perchlorates. Is hydrolyzed by dilute acids and by invertase (a yeast enzyme) . Chars rapidly and exothermically when mixed with concentrated sulfuric acid.

Hazard

Dental erosion. Questionable carcinogen.

Health Hazard

None

Pharmazeutische Anwendungen

Sucrose is widely used in oral pharmaceutical formulations. Sucrose syrup, containing 50–67% w/w sucrose, is used in tableting as a binding agent for wet granulation. In the powdered form, sucrose serves as a dry binder (2–20% w/w) or as a bulking agent and sweetener in chewable tablets and lozenges. Tablets that contain large amounts of sucrose may harden to give poor disintegration.
Sucrose syrups are used as tablet-coating agents at concentrations between 50% and 67% w/w. With higher concentrations, partial inversion of sucrose occurs, which makes sugar coating difficult.
Sucrose syrups are also widely used as vehicles in oral liquiddosage forms to enhance palatability or to increase viscosity.(4,5) Sucrose has been used as a diluent in freeze-dried protein products.
Sucrose is also widely used in foods and confectionery, and therapeutically in sugar pastes that are used to promote wound healing.

Landwirtschaftliche Anwendung

is obtained from sugar beet, sugar cane and sweet sorghum. Table sugar is the most common form of sucrose. It comprises a glucose unit joined to a fructose unit. Honey consists of sucrose and its hydrolysis products.
Sucrose, glucose and fructose all exhibit optical activity. When sucrose is hydrolyzed, the rotation changes from right to left. This is called inversion, and an equimolar mixture of glucose and fructose is called invert sugar. The enzyme invertase hydrolyzes sucrose to glucose and fructose.
Sugar occurs universally throughout the plant kingdom in fruits, seeds, flowers and roots.

Sicherheitsprofil

Mildly toxic by ingestion. An experimental teratogen. Mutation data reported. Vigorous reaction with nitric acid or sulfuric acid (forms carbon monoxide and carbon dioxide). When heated to decomposition it emits acrid smoke and irritating fumes.

Sicherheit(Safety)

Sucrose is hydrolyzed in the small intestine by the enzyme sucrase to yield dextrose and fructose, which are then absorbed. When administered intravenously, sucrose is excreted unchanged in the urine.
Although sucrose is very widely used in foods and pharmaceutical formulations, sucrose consumption is a cause of concern and should be monitored in patients with diabetes mellitus or other metabolic sugar intolerance.
Sucrose is also considered to be more cariogenic than other carbohydrates since it is more easily converted to dental plaque. For this reason, its use in oral pharmaceutical formulations is declining. Although sucrose has been associated with obesity, renal damage, and a number of other diseases, conclusive evidence linking sucrose intake with some diseases could not be established.( 13,14) It was, however, recommended that sucrose intake in the diet should be reduced.
LD50 (mouse, IP): 14 g/kg
LD50 (rat, oral): 29.7 g/kg

Lager

Sucrose has good stability at room temperature and at moderate relative humidity. It absorbs up to 1% moisture, which is released upon heating at 90°C. Sucrose caramelizes when heated to temperatures above 160°C. Dilute sucrose solutions are liable to fermentation by microorganisms but resist decomposition at higher concentrations, e.g. above 60% w/w concentration. Aqueous solutions may be sterilized by autoclaving or filtration.
When sucrose is used as a base for medicated confectionery, the cooking process, at temperatures rising from 110 to 145℃, causes some inversion to form dextrose and fructose (invert sugar). The fructose imparts stickiness to confectionery but prevents cloudiness due to graining. Inversion is accelerated particularly at temperatures above 130°C and by the presence of acids.

läuterung methode

Crystallise D(+)-sucrose from water (solubility: 1g in 0.5mL H2O at 20o, 1g in 0.2mL in boiling H2O). It is soluble in EtOH (0.6%) and MeOH (1%). Sucrose diacetate hexaisobutyrate is purified by melting and, while molten, treated with NaHCO3 and charcoal, then filtered. [Beilstein 17/8 V 399.]

Inkompatibilitäten

Powdered sucrose may be contaminated with traces of heavy metals, which can lead to incompatibility with active ingredients, e.g. ascorbic acid. Sucrose may also be contaminated with sulfite from the refining process. With high sulfite content, color changes can occur in sugar-coated tablets; for certain colors used in sugarcoating the maximum limit for sulfite content, calculated as sulfur, is 1 ppm. In the presence of dilute or concentrated acids, sucrose is hydrolyzed or inverted to dextrose and fructose (invert sugar). Sucrose may attack aluminum closures.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (injections; oral capsules, solutions, syrups, and tablets; topical preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Saccharose Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Saccharose Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 643)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971
deasea125996@gmail.com China 2503 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 2991 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 1000 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20391 58
Apeloa production Co.,Limited
+8619933239880
admin@apcl.com.cn China 354 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3002 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21686 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@
sales03@shyrchem.com CHINA 738 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3620 58

57-50-1(Saccharose)Verwandte Suche:


  • SUCROSE CONFECTIONERS
  • SUCROSE
  • SUCROSE SOLUTION
  • SUCROSE STANDARD
  • (alpha-D-Glucosido)-beta-D-fructofuranoside
  • .alpha.-D-Glucopyranoside,.beta.-D-fructofuranosyl
  • alpha-d-glucopyranoside,beta-d-fructofuranosyl
  • amerfand
  • Amerfond
  • beta-D-Fructofuranoside, alpha-D-glucopyranosyl
  • beta-d-fructofuranoside,alpha-d-glucopyranosyl
  • confectioner’ssugar
  • Confectioner's sugar
  • D-(+)-Saccharose bp ph.eur
  • -D-Fructofuranosyl-D-glucopyra-noside
  • Fructofuranoside, alpha-D-glucopyranosyl, beta-D
  • fructofuranoside,alpha-d-glucopyranosyl,beta-d
  • Glucopyranoside, beta-D-fructofuranosyl, alpha-D
  • glucopyranoside,beta-d-fructofuranosyl,alpha-d
  • granulatedsugar
  • Microse
  • NCI-C56597
  • Rock candy
  • rockcandy
  • Sugartab
  • White sugar Enovit M
  • whitesugar
  • SucroseWhite
  • D(+)-Sucrose, for analysis ACS
  • D(+)-Sucrose, for analysis, 99+%
  • D(+)-Sucrose, for biochemistry, 99.7%
  • D(+)-Sucrose, RNAse free and DNAse free, for biochemistry, 99+%
  • SUCROSE REAGENT (ACS)
  • SUCROSE,BIOTECHGRADE
  • SUCROSE,CRYSTAL,FCC
  • SUCROSE,CRYSTAL,NF
  • SUCROSE,CRYSTAL,REAGENT,ACS
  • (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • Surose
  • SUGARDUST
  • SUCROSECHEWINGGUM
  • SUCROSESYRUP
  • D(+)-SACCHAROSE
  • D(+)-SUCROSE
  • beta-d-fructofuranose-(2-1)-alpha-d-glucopyranoside
  • BETA-D-FRUCTOFURANOSYL-ALPHA-D-GLUCOPYRANOSIDE
  • D-(+)-SUCROSE, PLANT CELL CULTURE TESTED
  • D-(+)-SUCROSE MOLEKULA BIOLOGY GRADE
  • SUCROSE N.F.
  • Sucrose Total Dust
  • Sucrose, respirable dust
  • SUCROSE extrapure AR
  • Sucrose, Crystal, Reagent
  • α-D-Glc-(1-2)-β-D-Fru, D(+)-Saccharose, Saccharum, Sugar, β-D-Fructofuranosyl-α-D-glucopyranoside, α-D-Glucopyranosyl β-D-fructofuranoside
  • α-D-Glc-(1-2)-β-D-Fru, D(+)-Saccharose, Sugar, β-D-Fructofuranosyl-α-D-glucopyranoside, α-D-Glucopyranosyl β-D-fructofuranoside
  • D(+)-Sucrose, 99.7%, for biochemistry
  • D(+)-Sucrose, 99+%, for analysis
  • D(+)-SUCROSE, 99+%, RNASE FREE AND DNASE FREE, FOR BIOCHEMISTRY
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