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Picolinamide

Picolinamide structure

CAS No.: 1452-77-3

Chemical Name:: Picolinamide

Synonyms: PICOLINAMIDE;2-PICOLINAMIDE;Picolinoylamide;PicolinaMide 98%;Picolinamide ,98%;2-Picolinamide>alpha-Picolinamide;TIMTEC-BB SBB008128;2-Carbamoylpyridine;Picolinic acid amide

CBNumber:: CB00124741

Molecular Formula:: C6H6N2O

Molecular Weight:: 122.12

MDL Number:: MFCD00023483

MOL File:: 1452-77-3.mol

MSDS File:: SDS

Last updated:2023-10-13 18:16:27

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Picolinamide Properties

Melting point	110 °C (dec.)(lit.)
Boiling point	143 °C / 20mmHg
Density	1.2236 (rough estimate)
refractive index	1.5350 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	pK1: 2.10(+1) (20°C)
form	Solid
color	White to Off-White
BRN	109617
CAS DataBase Reference	1452-77-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	I3550CCL59
EPA Substance Registry System	2-Pyridinecarboxamide (1452-77-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

TSCA

Yes

HS Code

29333990

NFPA 704

	0
2		0

Picolinamide price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	104051	Picolinamide 98%	1452-77-3	10g	$49.8	2024-03-01	Buy
Sigma-Aldrich	104051	Picolinamide 98%	1452-77-3	50g	$237	2024-03-01	Buy
TCI Chemical	P0414	2-Picolinamide >98.0%(HPLC)(T)	1452-77-3	25g	$105	2024-03-01	Buy
Alfa Aesar	A15410	Pyridine-2-carboxamide, 98%	1452-77-3	5g	$43.65	2024-03-01	Buy
Alfa Aesar	A15410	Pyridine-2-carboxamide, 98%	1452-77-3	25g	$169.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
104051	10g	$49.8	Buy
104051	50g	$237	Buy
P0414	25g	$105	Buy
A15410	5g	$43.65	Buy
A15410	25g	$169.65	Buy

Picolinamide Chemical Properties,Uses,Production

Description

Picolinamide is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.

Uses

Picolinamide is a nicotinic acid derivative for prevention and treatment of cancer by activating RUNX3 gene.

Preparation

Picolinamide is prepared by processes that include coupling together a 4-methoxy-3-acyloxypicolinic acid with key 2-amino-L-alaninate esters derived from substituted 2-phenylethanols.

Pharmacology

picolinamide is a poly (adp-ribose) synthetase (parp) inhibitor. Parp inhibitors, a group of pharmacological inhibitors of the enzyme poly adp ribose polymerase (parp), are developed for multiple indications, especially for the treatment of cancer.

Picolinamide Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Potassium carbonate Dichloromethane Dimethyl sulfoxide Sodium hydroxide

2-Cyanopyridine Sulfuric acid Methanol Carbon dioxide Dimethyl carbonate

Methyl picolinate

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Preparation Products

2-Pyridinecarboxamide, N-cyclohexyl-

Picolinamide Suppliers

Global( 230)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Standardpharm Co. Ltd.	58

View Lastest Price from Picolinamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-17	N-BENZYL-4-(BENZYLAMINO)PICOLINAMIDE 913836-29-0	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2021-10-11	N-BENZYL-4-(BENZYLAMINO)PICOLINAMIDE 913836-29-0	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2020-02-17	N-(2-cyanophenyl)picolinaMide 304650-02-0	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

N-BENZYL-4-(BENZYLAMINO)PICOLINAMIDE
913836-29-0
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

N-BENZYL-4-(BENZYLAMINO)PICOLINAMIDE
913836-29-0
US $1.10 / g
99.00%
Dideu Industries Group Limited

N-(2-cyanophenyl)picolinaMide
304650-02-0
US $7.00 / KG
99%
Career Henan Chemical Co

PYRIDINE-2-CARBOXAMIDE Spectrum

PYRIDINE-2-CARBOXAMIDE(1452-77-3)MS PYRIDINE-2-CARBOXAMIDE(1452-77-3)¹HNMR PYRIDINE-2-CARBOXAMIDE(1452-77-3)¹³CNMR PYRIDINE-2-CARBOXAMIDE(1452-77-3)IR1 PYRIDINE-2-CARBOXAMIDE(1452-77-3)IR2 PYRIDINE-2-CARBOXAMIDE(1452-77-3)Raman

1452-77-3(Picolinamide)Related Search:

PYRIDINE-2-CARBOXYLIC ACID HYDRAZIDE Isonicotinamide Nicotinamide 2,4-Pyridinedicarboxylic acid, 2-Methyl ester Pyridine hydrofluoride

4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE 3-(2-PYRIDYL)ACRYLIC ACID Nicotinic acid NAD+ β-Nicotinamide Mononucleotide

Nicotinamide-N-oxide 3-Cyanopyridine Pyridine-3-sulfonyl chloride hydrochloride PYRIDINE-3-SULFONIC ACID SODIUM SALT PYRIDINE-2,4-DICARBONITRILE

Pyridine, 4-(diethylboryl)- Pyridine, 3-(3-ethoxyandrosta-5,16-dien-17-yl)- Pyridine, 3-[3-(1-methylethoxy)androsta-5,16-dien-17-yl]- Picolinamide

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alpha-Picolinic acid amide Picolinic acid amide Picolinoylamide Pyridine-2-carboxylicamide 2-PYRIDINECARBOXAMIDE 2-PICOLINAMIDE PICOLINAMIDE PYRIDINE-2-CARBOXYLIC ACID AMIDE PYRIDINE-2-CARBOXAMIDE TIMTEC-BB SBB008128 Picolinamide ,98% Picolinamide,2-Pyridinecarboxamide PicolinaMide 98% 2-Carbamoylpyridine alpha-Picolinamide Isoniazid Impurity I Nicotinamide EP Impurity C Nicotinamide Impurity 3(Nicotinamide EP Impurity C) 2-Picolinamide> 2-Picolinamide, 98%, for synthesis PYRIDINE-2-CARBOXAMIDE ISO 9001：2015 REACH 2-aminocarbonyl-pyridine 2-Pyridinecarboxamide (9CI, ACI) pyridine-2-carboxamide (picolinamide) Nicotinamide Impurity C Nicotinamide EP Impurity C（Picolinamide） Pyridin-2-carboxamide 1452-77-3 Heterocyclic Building Blocks Pyridines C6 Building Blocks Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Heterocyclic Compounds