ChemicalBook >> CAS DataBase List >>N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt structure

CAS No.: 150374-95-1

Chemical Name:: N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt

Synonyms: ONO5046-Na;EI546 sodium;LY544349 sodium;SIVELESTAT SODIUM;Sodium sivelestat;Sivelestat sodium sa;Sivelestat sodium salt;Sivelestat SodiuM anhydrous;N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt;sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate

CBNumber:: CB02131171

Molecular Formula:: C20H21N2NaO7S

Molecular Weight:: 456.44

MDL Number:

MOL File:: 150374-95-1.mol

Last updated:2023-06-30 15:45:59

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N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Properties

Melting point	104-108 °C(Solv: water (7732-18-5))
storage temp.	Desiccate at RT
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
FDA UNII	0CLL4232KD

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	3535	Sivelestatsodiumsalt ≥98%(HPLC)	150374-95-1	10	$125	2021-12-16	Buy
Tocris	3535	Sivelestatsodiumsalt ≥98%(HPLC)	150374-95-1	50	$526	2021-12-16	Buy
Usbiological	256675	Sivelestat sodium salt	150374-95-1	10mg	$366	2021-12-16	Buy
TRC	S497060	SivelestatSodium	150374-95-1	5mg	$50	2021-12-16	Buy
ChemScene	CS-2920	Sivelestatsodium 99.13%	150374-95-1	10mg	$84	2021-12-16	Buy

Product number	Packaging	Price	Buy
3535	10	$125	Buy
3535	50	$526	Buy
256675	10mg	$366	Buy
S497060	5mg	$50	Buy
CS-2920	10mg	$84	Buy

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Chemical Properties,Uses,Production

Uses

Sivelestat Sodium is an inhibitor of neutrophil elastase. Also, it is a promising therapeutic agent for severe acute pneumonitis caused by gefitinib.

Uses

Treatment of acute lung injury; acute respiratory distress syndrome (elastase inhibitor).

Biological Activity

Selective leukocyte elastase inhibitor (IC 50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF- κ B activation and LTB 4 -induced neutrophil transmigration in vitro . Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo .

storage

Desiccate at RT

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Suppliers

Global( 74)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15956	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	27945	58
AFINE CHEMICALS LIMITED	0571-85134551 18958018566;	info@afinechem.com	China	15377	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
InvivoChem	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

150374-95-1(N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt)Related Search:

ETHANE Chlorodimethylphenylsilane 4-Hydroxy-D-(-)-2-phenylglycine Benzoyl chloride Dimethyl sulfoxide

Montelukast sodium Sulfuryl chloride Dimethyldimethoxysilane Sodium hydroxide Sodium citrate

Sivelestat Sodium sulfate BENZOYL ISOCYANATE Dimethyl fumarate Diclofenac sodium

Imipenem-Cilastatin sodium hydrate Diethoxydimethylsilane Sodium benzoate

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n-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(s)-glycine monosodium salt SIVELESTAT SODIUM N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt Sivelestat sodium salt Glycine, N-[2-[[[4-(2,2-diMethyl-1-oxopropoxy)phenyl]sulfonyl]aMino]benzoyl]-, MonosodiuM salt Sivelestat SodiuM anhydrous sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate sodium 2-[[[2-[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonylamino]phenyl]-oxomethyl]amino]acetate N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt USP/EP/BP Sivelestat sodium sa EI546 sodium LY544349 sodium ONO5046-Na Sodium sivelestat 150374-95-1 GYL