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Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- structure

CAS No.: 211555-08-7

Chemical Name:: Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-

Synonyms: Janex 3;WHI-P180, >98%;WHI-P180(Janex 3);WHI P180;JANEX3;WHIP180;JANEX-3;3-(6,7-dimethoxyquinazolin-4-ylamino)phenol;3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol;Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-;3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol (Related Reference);WHI-P-180,HER1,Janex3,WHI P180,RET,EGFR,Vascular endothelial growth factor receptor,Inhibitor,Janex-3,WHIP180,inhibit,WHI-P180,VEGFR,ErbB-1,Epidermal growth factor receptor

CBNumber:: CB02667258

Molecular Formula:: C16H15N3O3

Molecular Weight:: 297.31

MDL Number:: MFCD02683970

MOL File:: 211555-08-7.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:20

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Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Properties

Boiling point	476.5±40.0 °C(Predicted)
Density	1.336±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
solubility	DMSO : 25 mg/mL (84.09 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form	Powder
pka	9.58±0.10(Predicted)

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	681500	WHI-P180 A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo.	211555-08-7	1MG	$259	2024-03-01	Buy
Cayman Chemical	23452	WHI-P180 ≥98%	211555-08-7	500μg	$93	2024-03-01	Buy
Cayman Chemical	23452	WHI-P180 ≥98%	211555-08-7	1mg	$176	2024-03-01	Buy
Cayman Chemical	23452	WHI-P180 ≥98%	211555-08-7	5mg	$684	2024-03-01	Buy
ChemScene	CS-1702	WHI-P180 99.76%	211555-08-7	50mg	$1080	2021-12-16	Buy

Product number	Packaging	Price	Buy
681500	1MG	$259	Buy
23452	500μg	$93	Buy
23452	1mg	$176	Buy
23452	5mg	$684	Buy
CS-1702	50mg	$1080	Buy

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Chemical Properties,Uses,Production

Biological Activity

WHI-P180 is an inhibitor of multiple kinases with IC50 values of 4.5 nM and 66 nM for RET (c-RET) and KDR, respectively.

in vivo

WHI-P180 is also an active inhibitor of IgE-mediated mast cell responses. The elimination half-life of WHI-P180 in CD-1 mice (BALB/c mice) following iv, ip, or po administration is less than 10 min. Systemic clearance of WHI-P180 is 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic ip bolus doses of 25 mg/kg, inhibits IgE/antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis.

target

Target	Value
RET (Cell-free assay)	4.5 nM
KDR (Cell-free assay)	66 nM

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Suppliers

Global( 79)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Alfa Chemistry	58
InvivoChem	58
Coresyn Pharmatech Co., Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-09-06	Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- 211555-08-7	US $1.00 / KG	1KG	98%	20kg	Career Henan Chemical Co

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
211555-08-7
US $1.00 / KG
98%
Career Henan Chemical Co

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Spectrum

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-(211555-08-7)¹HNMR

211555-08-7(Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-)Related Search:

4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL WEHI-345 JAK3 INHIBITOR II JAK3 INHIBITOR I 4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE

WH-4-023 7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE 3,4-Dimethoxyphenethylamine 2-Methylsulfonyl-4,6-dimethoxypyrimidine WHI-P97

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE JAK3 Inhibitor

1of3

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- 3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol Janex 3 3-(6,7-dimethoxyquinazolin-4-ylamino)phenol 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol (Related Reference) WHI P180;JANEX3;WHIP180;JANEX-3 WHI-P180(Janex 3) WHI-P180, >98% WHI-P-180,HER1,Janex3,WHI P180,RET,EGFR,Vascular endothelial growth factor receptor,Inhibitor,Janex-3,WHIP180,inhibit,WHI-P180,VEGFR,ErbB-1,Epidermal growth factor receptor 211555-08-7 Inhibitors