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Volitinib

Volitinib Structure
Volitinib structure
CAS No.
1313725-88-0
Chemical Name:
Volitinib
Synonyms
Savolitinib;HMPL-504;Savolitinib (AZD6094);CS-2676;Volitinib;AZD-6094);EOS-60799;HMPL0-504;Volitinib USP/EP/BP;AZD-6094 (VOLITINIB)
CBNumber:
CB02731160
Molecular Formula:
C17H15N9
Molecular Weight:
345.36
MDL Number:
MFCD28359096
MOL File:
1313725-88-0.mol
Last updated:2023-09-20 16:43:00
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Volitinib Properties

Melting point 205-207°C
Density 1.55±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka 5.67±0.50(Predicted)
form Solid
color Pale Beige
CAS DataBase Reference 1313725-88-0
FDA UNII 2A2DA6857R
NCI Drug Dictionary savolitinib

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360D

Volitinib price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC S142903 Savolitinib 1313725-88-0 100mg $1215 2021-12-16 Buy
ChemScene CS-4062 Savolitinib 99.56% 1313725-88-0 100mg $850 2021-12-16 Buy
ChemScene CS-4062 Savolitinib 99.56% 1313725-88-0 5mg $100 2021-12-16 Buy
Biosynth Carbosynth BV160378 Volitinib 1313725-88-0 5mg $100 2021-12-16 Buy
Biosynth Carbosynth BV160378 Volitinib 1313725-88-0 50mg $600 2021-12-16 Buy
Product number Packaging Price Buy
S142903 100mg $1215 Buy
CS-4062 100mg $850 Buy
CS-4062 5mg $100 Buy
BV160378 5mg $100 Buy
BV160378 50mg $600 Buy

Volitinib Chemical Properties,Uses,Production

Description

Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.

Uses

Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.

Clinical Use

It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.

Volitinib synthesis

3167-49-5
1313725-88-0
Synthesis of Volitinib from 6-Aminonicotinic acid

Volitinib Preparation Products And Raw materials

Raw materials

N-methoxy-N-methylimidazo[1,2-a]pyridine-6-carboxamide IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID 1-Methyl-4-pyrazole boronic acid pinacol ester 6-Aminonicotinic acid

Preparation Products

Volitinib(enantiomer)

Volitinib Suppliers

Global( 127)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12471 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 28455 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118 xie@china-sinoway.com China 992 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hong Kong Tiansheng New Material Trading Co., Ltd 		+8617320695765 zxx@hktiansheng.com China 981 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
career henan chemical co 		58
Hebei Mojin Biotechnology Co., Ltd 		58
Dideu Industries Group Limited 		58
Sinoway Industrial co., ltd. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Hong Kong Tiansheng New Material Trading Co., Ltd 		58

View Lastest Price from Volitinib manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pharmaceutical Intermediate Volitinib pictures 2023-01-31 Pharmaceutical Intermediate Volitinib
1313725-88-0
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Savolitinib pictures 2022-02-25 Savolitinib
1313725-88-0
 US $38.99 / KG 1KG 99% 100KG Hong Kong Tiansheng New Material Trading Co., Ltd
Volitinib USP/EP/BP pictures 2021-07-06 Volitinib USP/EP/BP
1313725-88-0
 US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
  • Savolitinib pictures
  • Savolitinib
    1313725-88-0
  • US $38.99 / KG
  • 99%
  • Hong Kong Tiansheng New Material Trading Co., Ltd

Volitinib Spectrum

Volitinib(1313725-88-0)1HNMR

1313725-88-0(Volitinib)Related Search:

PLX4032 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol Ibrutinib SU 6668 3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione
INCB39110 X-376 Filgotinib Decernotinib Masitinib
Lestaurtinib CAL-101 PLX3397 (Pexidartinib) CO-1686 Momelotinib
AZD-6244 ARRY-334543 Verteporfin

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AZD6094,Volitinib, HMPL-504, Savolitinib 1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine (S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine Volitinib HMPL-504(AZD6094, Volitinib) EOS-60799 AZD-6094) Savolitinib (Volitinib (S)-1-(1-(imidazo[1,2-a] yridine-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (S)-1-(1-(IMIDAZO[1,2-A] HMPL-504; HMPL504; HMPL504; AZD-6094; AZD 6094; AZD6094 Volitinib (Savolitinib, AZD-6094) CS-2676 VOLITINIB; HMPL504; AZD-6094;VOLITINIB; HMPL-504; AZD6094; HMPL 504; AZD 6094 Savolitinib(AZD6094, HMPL-504) 1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)- Volitinib USP/EP/BP 4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[ 1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyra zole Savolitinib HMPL-504 Savolitinib (AZD6094) Pharmaceutical Intermediate Volitinib AZD-6094 (VOLITINIB) VOLITINIB (AZD6094, SAVOLITINIB) HMPL0-504 1313725-88-0 API