Erlotinib D6 HCl
- CAS No.
- 1189953-78-3
- Chemical Name:
- Erlotinib D6 HCl
- Synonyms
- Erlotinib D6;OSI-774 D6 hydrochloride;Erlotiniβ-d6 Hydrochloride;CP-358774 D6 hydrochloride;NSC 718781 D6 hydrochloride;[2H6]-Erlotinib Hydrochloride;Erlotinib Hydrochloride Impurity G
- CBNumber:
- CB03049808
- Molecular Formula:
- C22H18ClD6N3O4
- Molecular Weight:
- 435.933630668
- MDL Number:
- MFCD09840535
- MOL File:
- 1189953-78-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
NFPA 704 |
|
Erlotinib D6 HCl price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 22101 | Erlotinib-d6 (hydrochloride) ≥99% deuterated forms (d1-d6) | 1189953-78-3 | 1mg | $279 | 2024-03-01 | Buy |
TRC | E625002 | Erlotinib-d6Hydrochloride | 1189953-78-3 | 1mg | $145 | 2021-12-16 | Buy |
AK Scientific | 7728DG | ErlotinibD6Hydrochloride | 1189953-78-3 | 1mg | $409 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006809 | ERLOTINIB-D6-HYDROCHLORIDE 95.00% | 1189953-78-3 | 10MG | $1871.1 | 2021-12-16 | Buy |
Erlotinib D6 HCl Chemical Properties,Uses,Production
Description
Erlotinib-d6 (hydrochloride) contains six deuterium atoms located on the methoxy group. It is intended for use as an internal standard for the quantification of erlotinib by GC- or LC-MS. Erlotinib is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. Formulations containing erlotinib are used to treat certain forms of cancer, including non-small cell lung cancer.
Uses
Erlotinib D6 HCl is a Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, Antineoplastic.;Labeled Erlotinib, intended for use as an internal standard for the quantification of Erlotinib by GC- or LC-mass spectrometry.
Erlotinib D6 HCl Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14335 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
SIMSON PHARMA LIMITED | +91-8291074273 | k.das@simsonpharma.com | India | 228 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 7183 | 65 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
Artis Biotech Co. Ltd. | 19138486554 18582380095 | sales@artisbio.com | China | 2964 | 58 |
View Lastest Price from Erlotinib D6 HCl manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-05-27 | Erlotinib-D6 Hydrochloride
1189953-78-3
|
US $0.00-0.00 / mg | 1mg | 96% | 50 mg | Simson Pharma limited |
- Erlotinib-D6 Hydrochloride
1189953-78-3
- US $0.00-0.00 / mg
- 96%
- Simson Pharma limited