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2-Acetamidophenol

2-Acetamidophenol structure

CAS No.: 614-80-2

Chemical Name:: 2-Acetamidophenol

Synonyms: NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol;O-ACETAMINOPHENOL;O-ACETAMIDOPHENOL;2-ACETAMIDOPHENOL;2-acetamido-pheno

CBNumber:: CB0342159

Molecular Formula:: C8H9NO2

Molecular Weight:: 151.16

MDL Number:: MFCD00002181

MOL File:: 614-80-2.mol

MSDS File:: SDS

Last updated:2023-08-17 18:11:45

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2-Acetamidophenol Properties

Melting point	205-210 °C(lit.)
Boiling point	273.17°C (rough estimate)
Density	1.2023 (rough estimate)
refractive index	1.5810 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Powder
pka	9.35±0.35(Predicted)
color	Off-white to beige to brown
BRN	607592
Stability	Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
CAS DataBase Reference	614-80-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	4AS8989RNI
NIST Chemistry Reference	Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA Substance Registry System	2'-Hydroxyacetanilide (614-80-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Xi,Xn

Risk Statements

36/38-22-36/37/38

Safety Statements

26-36-37/39

RIDADR

2811

WGK Germany

RTECS

AE4025000

1-8

TSCA

Yes

HazardClass

6.1(b)

PackingGroup

III

HS Code

29242995

NFPA 704

	1
2		0

2-Acetamidophenol price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A7000	2-Acetamidophenol 97%	614-80-2	25g	$48.7	2024-03-01	Buy
Sigma-Aldrich	A7000	2-Acetamidophenol 97%	614-80-2	100g	$90.1	2024-03-01	Buy
Sigma-Aldrich	1003031	Acetaminophen Related Compound C United States Pharmacopeia (USP) Reference Standard	614-80-2	50mg	$1380	2024-03-01	Buy
TCI Chemical	H0189	2'-Hydroxyacetanilide >99.0%(HPLC)(N)	614-80-2	25g	$68	2024-03-01	Buy
Alfa Aesar	B21264	2-Acetamidophenol, 97%	614-80-2	25g	$22.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
A7000	25g	$48.7	Buy
A7000	100g	$90.1	Buy
1003031	50mg	$1380	Buy
H0189	25g	$68	Buy
B21264	25g	$22.65	Buy

2-Acetamidophenol Chemical Properties,Uses,Production

Chemical Properties

white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.

Uses

An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.

Preparation

Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.

Definition

ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol synthesis

Synthesis of 2-Acetamidophenol from Acetic anhydride and 2-Aminophenol

2-Acetamidophenol Preparation Products And Raw materials

Raw materials

2-Aminophenol Acetic anhydride

Preparation Products

4-Bromo-2-hydroxybenzoic acid 2-Methylbenzoxazole 6-BROMO-2H-1,4-BENZOXAZIN-3(4H)-ONE N-(2-Butyloxyphenyl)acetamide DIMETHYL 2-(4-METHOXYBENZYL)MALONATE

2-Acetamidophenol Suppliers

Global( 318)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Xi'an Kono chem co., Ltd.,	58
Standardpharm Co. Ltd.	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2-Acetamidophenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-09-06	2-Acetamidophenol 614-80-2	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.
2023-08-18	2-Acetamidophenol 614-80-2	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-02-13	acetoaminophenol 614-80-2	US $50.00 / kg	1kg	99%	50MT	Hebei baicao biology science and technology co., ltd

2-Acetamidophenol
614-80-2
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

2-Acetamidophenol
614-80-2
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

acetoaminophenol
614-80-2
US $50.00 / kg
99%
Hebei baicao biology science and technology co., ltd

2-Acetamidophenol Spectrum

2-Acetamidophenol(614-80-2)MS 2-Acetamidophenol(614-80-2)¹HNMR 2-Acetamidophenol(614-80-2)IR1 2-Acetamidophenol(614-80-2)IR2 2-Acetamidophenol(614-80-2)Raman

614-80-2(2-Acetamidophenol)Related Search:

2-Chloro-4-acetamidophenol 4'-Aminoacetanilide 4'-Nitroacetanilide Acetamide 4-Hydroxyaniline hydrochloride

3-Diethylaminophenol p-Acetotoluidide 2-BENZOYLACETANILIDE 2-ACETAMIDOFLUORENE 4-Aminophenol

2-Aminophenol ACETAMINOPHEN IMPURITY B 4,4'-Iminodiphenol hydrochloride 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one 4'-CHLOROACETANILIDE

4'-Hydroxyacetophenone 2'-Hydroxyacetophenone 4-Acetoxyacetanilide

1of4

2-ACETYLAMINOPHENOL 2-ACETAMIDOPHENOL 2-ACETAMINO PHENOL Acetaminophen Related Compound C (50 mg) (N-(2-hydroxyphenyl)acetamide) AKOS BBB/377 O-HYDROXYACETANILIDE O-ACETAMIDOPHENOL O-ACETAMINOPHENOL N-(2-Hydroxyphenyl)acetamide 2'-HYDROXYACETANILIDE 2-HYDROXYACETANILIDE 2’-hydroxy-acetanilid 2-acetamido-pheno 2-Hydroxyanilid kyseliny octove 2-hydroxyanilidkyselinyoctove Acetanilide, 2'-hydroxy- Acet-o-aminofenol n-(2-hydroxyphenyl)-acetamid N-(2-hydroxyphenyl)ethanamide N-Acetyl-2-aminophenol N-Acetyl-o-aminophenol o-(Acetylamino)phenol o-Acetylaminofenol Phenol, 2-acetamido- 2-Acetamidophenol99% 2-Acetamidophenol,97% 2-(N-Acetylamino)phenol NSC 398 2-Acetamino o-Acetamidophenol AP ORTHO-HYDROXYACETANILIDE 2-HYDROXYACETANILIDE / 2-ACETAMIDOPHENOL NSC 3989 o-Aminophenol N-acetate 2-Acetamide phenol O AcetaMinophen ParacetaMol IMpurity A 2-AcetaMidophenol, 98.5% AcetaMinophen Related CoMpound C Paracetamol EP Impurity A(2-Acetamidophenol) Paracetamol EP Impurity A Paracetamol Impurity 1(Paracetamol EP Impurity A) 2'-Hydroxyacetanilide> N-(2-Hydroxyphenyl)acetamide (2-Ace Acetamide, N-(2-hydroxyphenyl)- acetoaminophenol Paracetamol(Acetaminophen) EP Impurity A Paracetamol EP Impurity Acetaminophen related compound C Paracetamol Impurity A Acetaminophen impurities1455 Acetaminophen EP Impurity A Acetaminophen Related Compound C (R00920) Acetaminophen Related Compound C (N-(2-hydroxyphenyl)acetamide) (1003031) Acetaminophen USP Related Compound C 2 Acetamidophenol,2Acetamidophenol Paracetamol EP Impurity A (Acetaminophen USP Related Compound C) Paracetamol EP Impurity A N-(2-hydroxyphenyl)acetamide 2'-Hydroxyacetanilide, ≥ 99.0%