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Phenetidine structure
Chemical Name:
cp5685;NSC 3116;Benzenam;phenetidine;p-Fenetidin;Phenethidine;p-Phenetidin;ethoxaniline;4-PHENETIDINE;P-PHENETIDINE
Molecular Formula:
Formula Weight:
MOL File:

Phenetidine Properties

Melting point:
2-5 °C(lit.)
Boiling point:
250 °C(lit.)
1.065 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.559(lit.)
Flash point:
240 °F
storage temp. 
5.2(at 28℃)
8 (1g/l, H2O, 20℃)
Water Solubility 
practically insoluble
Air Sensitive
Stability Stable, but light and air sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
156-43-4(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
Benzenamine, 4-ethoxy-(156-43-4)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  T,Xi,Xn
Risk Statements  23/24/25-33-68-43-36-20/21/22
Safety Statements  28-36/37-45-46
RIDADR  UN 2311 6.1/PG 3
WGK Germany  1
RTECS  SI6465500
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  III
HS Code  29222200
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P391 Collect spillage. Hazardous to the aquatic environment
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

NFPA 704

Diamond Hazard Value Description
Flammability   1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

Phenetidine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P14815 4-Ethoxyaniline 98% 156-43-4 100g $24.9 2018-11-13 Buy
Sigma-Aldrich P14815 4-Ethoxyaniline 98% 156-43-4 500g $55.8 2018-11-13 Buy
TCI Chemical P0090 p-Phenetidine >98.0%(GC) 156-43-4 25g $29 2018-11-22 Buy
TCI Chemical P0090 p-Phenetidine >98.0%(GC) 156-43-4 500g $103 2018-11-22 Buy

Phenetidine Chemical Properties,Uses,Production

Chemical Properties

colourless liquid


A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.


ChEBI: An aromatic ether that is aniline in which the hydrogen at position 4 is replaced by an ethoxy group. It is a hydrolysis metabolite of phenacetin.

General Description

Colorless to dark red liquid.

Air & Water Reactions

Very sensitive to exposure to air and light. Turns red to brown on exposure to light and air. . Slightly soluble in water.

Reactivity Profile

Phenetidine reacts vigorously with powerful oxidizers.

Fire Hazard

Phenetidine is combustible.

Safety Profile

Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. Caution: It can be absorbed through the skin. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Phenetidine Preparation Products And Raw materials

Raw materials

Preparation Products

Phenetidine Suppliers

Global( 189)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21954 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20095 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4669 58
Suzhou Ryan Pharmaceutical Technology Co., Ltd. +86-512-68780025
+86-512-68780026 China 103 62
Suzhou Aibote Chemical Co., Ltd. 15250011737 China 136 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76

Phenetidine Spectrum

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