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L-Malic acid

L-Malic acid Structure
L-Malic acid structure
CAS No.
97-67-6
Chemical Name:
L-Malic acid
Synonyms
L-MALIC ACID;L-Malic;(2S)-2-hydroxybutanedioic acid;L-Mailcacid;HYDROXYBUTANEDIOIC ACID;L-Gydroxybutanedioicacid;apple acid;pinguosuan;(S)-(-)-MALIC ACID;-(-)-MaL
CBNumber:
CB0493594
Molecular Formula:
C4H6O5
Molecular Weight:
134.09
MDL Number:
MFCD00064213
MOL File:
97-67-6.mol
MSDS File:
SDS
Last updated:2024-04-23 14:28:52
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L-Malic acid Properties

Melting point 101-103 °C (lit.)
Boiling point 167.16°C (rough estimate)
alpha -2 º (c=8.5, H2O)
Density 1.60
vapor pressure 0Pa at 25℃
FEMA 2655 | L-MALIC ACID
refractive index -6.5 ° (C=10, Acetone)
Flash point 220 °C
storage temp. Store below +30°C.
solubility H2O: 0.5 M at 20 °C, clear, colorless
form Powder
Specific Gravity 1.595 (20/4℃)
color White
PH 2.2 (10g/l, H2O, 20℃)
pka (1) 3.46, (2) 5.10(at 25℃)
Odor odorless
Odor Type odorless
optical activity [α]20/D 30±2°, c = 5.5% in pyridine
Water Solubility soluble
JECFA Number 619
Merck 14,5707
BRN 1723541
InChIKey BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP -1.68
Substances Added to Food (formerly EAFUS) L-MALIC ACID
SCOGS (Select Committee on GRAS Substances) L-Malic acid
CAS DataBase Reference 97-67-6(CAS DataBase Reference)
FDA UNII J3TZF807X5
NIST Chemistry Reference Butanedioic acid, hydroxy-, (s)-(97-67-6)
EPA Substance Registry System Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  ON7175000
TSCA  Yes
HS Code  29181980
NFPA 704
0
2 0

L-Malic acid price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.00384 L-(-)-Malic acid for resolution of racemates for synthesis 97-67-6 5G $27.2 2024-03-01 Buy
Sigma-Aldrich 8.00384 L-(-)-Malic acid for resolution of racemates for synthesis 97-67-6 10g $39.7 2024-03-01 Buy
Sigma-Aldrich 8.00384 L-(-)-Malic acid for resolution of racemates for synthesis 97-67-6 50g $99.8 2024-03-01 Buy
Sigma-Aldrich 8.00384 L-(-)-Malic acid for resolution of racemates for synthesis 97-67-6 500g $411 2024-03-01 Buy
Sigma-Aldrich 8.00384 L-(-)-Malic acid for resolution of racemates for synthesis 97-67-6 1kg $801 2024-03-01 Buy
Product number Packaging Price Buy
8.00384 5G $27.2 Buy
8.00384 10g $39.7 Buy
8.00384 50g $99.8 Buy
8.00384 500g $411 Buy
8.00384 1kg $801 Buy

L-Malic acid Chemical Properties,Uses,Production

Description

L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.

Chemical Properties

L-Malic acid is nearly odorless (sometimes a faint, acrid odor). This compound has a tart, acidic, nonpungent taste.

Chemical Properties

clear colourless solution

Occurrence

Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.

Uses

The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece

Uses

L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.

Uses

Intermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.

Preparation

L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.

Definition

ChEBI: An optically active form of malic acid having (S)-configuration.

General Description

L-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.

Biochem/physiol Actions

L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

Purification Methods

Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]

L-Malic acid synthesis

1009815-87-5
640-68-6
72-18-4
97-67-6
1127229-10-0
1127229-09-7
56-40-6
Synthesis of L-Malic acid from Largazole

L-Malic acid Preparation Products And Raw materials

Raw materials

Calcium carbonate Disodium fumarate Poly(acrylic acid) (2S)-1-(3-Acetylthio-2-methyl-1-oxopropyl)-L-proline

Preparation Products

Fluorescent Brightener 135 (S)-(+)-3-Hydroxytetrahydrofuran (-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID (R)-(-)-3-Quinuclidinol (S)-1-Benzyl-3-pyrrolidinol
(S)-3-Hydroxypyrrolidine hydrochloride Diethyl malate (R)-3-Quinuclidinol hydrochloride Coumalic acid CHLOROSUCCINIC ACID
2,5-Pyrrolidinedione, 3-(acetyloxy)-, (3S)- Butanedioic acid, 2-hydroxy-, 1-(phenylmethyl) ester, (2S)- Cabozantinib Malate

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L-Malic acid Suppliers

Global( 693)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd
510-85010237 overseamarketing@alphahi-tech.com CHINA 41 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040 sales@myuchem.com China 6710 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 994 58
Hebei Jingbo New Material Technology Co., Ltd 		+8619931165850 hbjbtech@163.com China 1000 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
airuikechemical co., ltd. 		+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618740459177 sarah@tnjone.com China 893 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 2259 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 476 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Supplier Advantage
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd
58
Shanghai UCHEM Inc.
58
Anhui Ruihan Technology Co., Ltd 		58
Hebei Jingbo New Material Technology Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
airuikechemical co., ltd. 		58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55

Related articles

View Lastest Price from L-Malic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Malic acid pictures 2024-04-23 L-Malic acid
97-67-6
 US $200.00-85.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
L-Malic Acid pictures 2024-04-22 L-Malic Acid
97-67-6
 US $0.00 / kg 1kg 99% 10000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
L-Malic acid pictures 2024-04-19 L-Malic acid
97-67-6
 US $50.00 / kg 1kg 99.10% 5000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
  • L-Malic acid pictures
  • L-Malic acid
    97-67-6
  • US $200.00-85.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
  • L-Malic Acid pictures
  • L-Malic Acid
    97-67-6
  • US $0.00 / kg
  • 99%
  • Shaanxi TNJONE Pharmaceutical Co., Ltd
  • L-Malic acid pictures
  • L-Malic acid
    97-67-6
  • US $50.00 / kg
  • 99.10%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd

L-Malic acid Spectrum

L-(-)-Malic Acid(97-67-6)MSL-(-)-Malic Acid(97-67-6)1HNMRL-(-)-Malic Acid(97-67-6)13CNMRL-(-)-Malic Acid(97-67-6)IR1L-(-)-Malic Acid(97-67-6)IR2L-(-)-Malic Acid(97-67-6)Raman

97-67-6(L-Malic acid)Related Search:

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Glycine D(+)-Malic acid Ascoric Acid Oxobutanedioic acid 3,4-dihydroxybutanoic acid
Malic acid 4-Me ester 2-HYDROXYSUCCINIC ACID METHYL ESTER L-Carnosine

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L(-)-Malic acid, 30 wt% aqueous solution Butanedioic acid, hydroxy-, (2S)- L-MALIC ACID L L-LYSINEMONOHCL L-MALIC ACID / (S)-(-)-HYDROXYSUCCINIC ACID (S)-(-)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid S-2-Hydroxybutanedioic acid )-Malic ac L-()-Malic ac L(-)-Malic acid, 99% 25GR L-2-Hydroxybutanedioic acid L-(-)-MALIC ACID FOR RESOLUTION OF RACEM L-(-)-Malic acid 95-100% (enzyMatic) L-(-)-Malic acid 97%, optical purity ee: 99% (GLC) L-(-)-Malic acid ReagentPlus(R), >=99% L-(-)-Malic Acid, 97+% L-(-)-Malicacid,98+% L-(-)-Malicacid,99% L-(-)-ALIC ACID, AQUEOUS SOLUTION L-(-)-Malic acid Vetec(TM) reagent grade, 97% malic acid ,Hydrozybutanedioic acid (S)-(-)-2-Hydroxysuccinic acid L-Hydroxybutanedioic acid Apple acid L-(-)-Apple Acid (S)-(-)-HYDROXYSUCCINIC ACID (S)-HYDROXYSUCCINIC ACID (S)-HYDROXYBUTANEDIOIC ACID (S)-2-HYDROXYBUTANEDICARBOXYLIC ACID S(-)-2-HYDROXYSUCCINIC ACID NATURAL APPLE ACID L-HYDROXYSUCCINIC ACID L-HYDROXYBUTANEDIOIC ACID L-(-)-APPLE ACID L-APPLE ACID L(-)-MALATE (-)-L-MALIC ACID L-(-)-MALIC ACID MALIC ACID, L-(-)- 2-HYDROXYSYCCINIC ACID 1-HYDROXYSUCCINIC ACID L-Maleic Acid L(+-)MALIC ACID FREE ACID INSECT CELL*CU LTURE TESTE L-MALIC ACID FREE ACID CRYSTALLINE L(-)MALIC ACID FREE ACID PLANT CELL*CULT URE TESTED L (-) MALIC ACID SIGMAULTRA L-MALIC ACID 99+% FCC L-MALIC ACID BIOTECH GRADE 99.5% Butanedioicacid,hydroxy-,(S)- hydroxy-,(S)-Butanedioicacid l-(ii)-malicacid L-(-)-MalicAcid> CultureSure L(-)-Malic Acid, Animal-derived-free -(-)-MaL (S)-malicaci L-(-)-Malic Acid ISO 9001：2015 REACH N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide L-malic acidQ: What is L-malic acid Q: What is the CAS Number of L-malic acid Q: What is the storage condition of L-malic acid Q: What are the applications of L-malic acid L-(-)-Malic acid, CP Butanedioic acid, 2-hydroxy-, (2S)- L-Gydroxybutanedioicacid