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ChemicalBook >> CAS DataBase List >>(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Structure
(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol structure
CAS No.
22348-32-9
Chemical Name:
(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
Synonyms
RDPP;(R)-DIPHENYL(PYRROLIDIN-2-YL)METHANOL;(R)-DIPHENYLPROLINOL;PYRROLIDINEMETHANOL;idinemethanoL;(R)-(+)-2-(Diphenylh;(R)-(+)-α,α-DiphenyL;Nebivolol Impurity 48;α,α-diphenyl-d-prolinol;(R)-1-DIPHENYL-PROLINOL
CBNumber:
CB1101689
Molecular Formula:
C17H19NO
Molecular Weight:
253.35
MDL Number:
MFCD00077754
MOL File:
22348-32-9.mol
MSDS File:
SDS
Last updated:2024-05-16 10:38:43
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(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Properties

Melting point 77-80 °C
alpha 59 º (589nm, c=3, MeOH 25 ºC)
Boiling point 396.54°C (rough estimate)
Density 1.0078 (rough estimate)
refractive index 58 ° (C=2, MeOH)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility almost transparency in Chloroform
form solid
pka 13.15±0.29(Predicted)
color white to off-white
optical activity [α]20/D +69°, c = 3 in chloroform
BRN 4353363
InChIKey OGCGXUGBDJGFFY-MRXNPFEDSA-N
CAS DataBase Reference 22348-32-9(CAS DataBase Reference)
FDA UNII D56JS74WW2
NIST Chemistry Reference (R)-alpha-(2-pyrrolidinyl)benzhydryl alcohol(22348-32-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
F  10-34
TSCA  No
HS Code  29221990
NFPA 704
1
2 0

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382337 (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol 98% 22348-32-9 1g $153.6 2024-03-01 Buy
Sigma-Aldrich 382337 (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol 98% 22348-32-9 5g $208 2024-03-01 Buy
TCI Chemical D2365 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol >98.0%(GC)(T) 22348-32-9 1g $131 2024-03-01 Buy
TCI Chemical D2365 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol >98.0%(GC)(T) 22348-32-9 5g $453 2024-03-01 Buy
Alfa Aesar L09218 (R)-(+)-alpha,alpha-Diphenylprolinol 99% 22348-32-9 1g $148 2023-06-20 Buy
Product number Packaging Price Buy
382337 1g $153.6 Buy
382337 5g $208 Buy
D2365 1g $131 Buy
D2365 5g $453 Buy
L09218 1g $148 Buy

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Chemical Properties,Uses,Production

Chemical Properties

white to faintly yellow crystalline powder

Uses

Used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones.

Uses

suzuki reaction

Definition

ChEBI: (r)-alpha,alpha-diphenyl-2-pyrrolidinemethanol is a diarylmethane.

Synthesis

Draw 14 kg of tetrahydrofuran into the reaction kettle. 61.5 kg of a 34% strength solution of phenylmagnesium chloride in tetrahydrofuran was added to the reaction vessel to initiate agitation and cooling cycles. The control temperature is 10 to 60 °C. The dropping time was controlled for 5 to 6 hours, and stirring was continued for 1 hour. Pump 24 kg of concentrated hydrochloric acid (mass concentration 36%) into the matching drip tank of the reaction kettle. constantly dropping, the dropping time is controlled for 1 hour, and the dropping process control temperature does not exceed 45 ° C. After the addition was completed, stirring was continued for 8 hours.Cool down to -5 ° C ~ 5 ° C to obtain (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol, a total of 17.2 kg, yield 85%.

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol synthesis

137496-68-5
22348-32-9
Synthesis of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol from 1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)-

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

R-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy] diphenylMethyl]-Pyrrolidine

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Suppliers

Global( 502)Suppliers
Supplier Tel Email Country ProdList Advantage
China Synchem Technology Co.,Ltd.
+86-0552-4929304 +86-18055277008 wangxuhui1985@126.com China 55 55
Kindchem(Nanjing)Co.,Ltd 		+86-025-025-85281586 +8618651653755 sales@kindchem.cn China 1227 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 2603 58
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15956 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21688 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Zjartschem 		+86-571-8723 8903 jocelynpan@zjarts.com jocelynpan@zjarts.com CHINA 993 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Supplier Advantage
China Synchem Technology Co.,Ltd.
55
Kindchem(Nanjing)Co.,Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Zjartschem 		58
career henan chemical co 		58

View Lastest Price from (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol pictures 2024-05-16 (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
22348-32-9
 US $32.00 / kg 1kg 99% 5000kg/week Hebei Zhuanglai Chemical Trading Co.,Ltd
(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol pictures 2024-01-17 (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
22348-32-9
 US $0.00-0.00 / G 10G 0.98 500kg Kindchem(Nanjing)Co.,Ltd
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol pictures 2023-09-06 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol
22348-32-9
 US $0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Spectrum

(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)MS(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)1HNMR(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)13CNMR(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)IR1(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)IR2(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)Raman

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?-DIPHENYL(PYRROLIDIN-2-YL)METHANOL (r)-(+)-à,à-diphenyl-2-pyrrolidinemethanol (r)-(+)-à,à-diphenylprolinol α,α-diphenyl-d-prolinol 2,2-DIPHENYL-(2R)-2-PYRROLIDINEMETHANOL (R)-(+)-alpha,alpha-diphenyl-2-pyrrolidine (R)-(+)-ALPHA,ALPHA-DIPHENYL-2-PRRROLIDINE METHANOL 99.0+% (+)-Diphenyl[(2R)-pyrrolidin-2-yl]methanol, (+)-alpha,alpha-Diphenyl-D-prolinol (R)-(+)- alpha,alpha-Diphenyl-2-yrrolidine Methanol -DIPHENYL(PYRROLIDIN-2-YL)METHANOL (R)-(+)-alpha,alpha-Diphenyl-2-Pymolidinemethanol (R)-(+)-α,α-Diphenyl-2-pyrrolidineMethanol 98% 2-PyrrolidineMethanol,a,a-diphenyl-, (2R)- (R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine alpha,alpha-Diphenyl-D-prolinol 2-Pyrrolidinemethanol, .alpha.,.alpha.-diphenyl-, (2R)- (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol 98% (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol, >=99% 2-PYRROLIDINEMETHANOL, A,A-DIPHENYL- diphenyl-[(2R)-pyrrolidin-2-yl]methanol 2-Pyrrolidinemethanol, α,α-diphenyl-, (2R)- (2R)-α,α-diphenyl-2-Pyrrolidinemethanol (R)-1-DIPHENYL-PROLINOL (R)-(+)-2-(DIPHENYLHYDROXYMETHYL)-PYRROLIDIN (R)-(+)-2-(DIPHENYLHYDROXYMETHYL)PYRROLIDINE (R)-2-(DIPHENYLHYDROXYMETHYL)PYRROLIDINE (R)-(+)-ɑ,ɑ-Diphenylprolinol, 99% ALPHA,ALPHA-DIPHENYL-D-PROLINOL A,A-DIPHENYL-D-PROLINOL alpha,alpha-diphenyl-2-pyrrolidinemethanol (R)-α,α-Diphenyl-2-pyrrolidinemethanol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine α,α-Diphenyl-D-prolinol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol,98% (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol ,98% α,α-Diphenyl-D-prolinol,(R)-α,α-Diphenyl-2-pyrrolidinemethanol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol,α,α-Diphenyl-D-prolinol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine (2R)-(+)-2-[Hydroxy(diphenyl)methyl]pyrrolidine (R)-(+)-2-(Diphenylh alpha-Diphenyl-2-pyrrolidineMethanol Diphenyl[(2R)-(+)-pyrrolidin-2-yl]methanol, (R)-(+)-alpha,alpha-Diphenylprolinol alpha,alpha-Diphenyl-D-prolinol (R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine -(+)-2-(DiphenylhydroxyMethyl)pyrrolidine R(+)-A,A-DIPHENYLPROLINOL R-(+)-ALFA,ALFA-DIPHENYL-2-PYRROLIDINE METHANOL (R)-(+)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL (R)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL (R)-(+)-ALPHA,ALPHA-DIPHENYL-(2-PYRROLIDINYL)-METHANOL (R)-(+)-ALPHA,ALPHA-DIPHENYLPROLINOL (R)-(+)-DIPHENYL-2-PYRROLIDINEMETHANOL (R)-(+)-DIPHENYLPYRROLIDINEMETHANOL (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol> (R)-(+)-a,a-2-Pyrrolidinemethanol R-(+)-α,α-Diphenylprolinol (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (R)-(+)- α,α-2-pyrrolidinemethanol iphenyl-[(2R)-pyrrolidin-2-yl]methanol (R)-1,1-Diphenylprolinol (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethan