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Ilomastat

Ilomastat
Ilomastat
CAS No.
142880-36-2
Chemical Name:
Ilomastat
Synonyms
SANTACRUZ;IlloMastat;sc-203979A;galardin tm;Ilomastat, >=98%;GM 6001 Ilomastat;Ilomastat (GM 6001);Galardin CS 610;IloMastat (GM6001, Galardin);Galardin, GM6001, Ilomastat
CBNumber:
CB11178927
Molecular Formula:
C20H28N4O4
Formula Weight:
388.47
MOL File:
142880-36-2.mol

Ilomastat Properties

storage temp. 
2-8°C
solubility 
Soluble in DMSO, and 100% ethanol.
form 
Off-white solid
Sensitive 
Moisture Sensitive
InChIKey
NITYDPDXAAFEIT-DYVFJYSZSA-N

SAFETY

Safety Statements  22-24/25
WGK Germany  3
HS Code  29339900

Ilomastat price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 364205 GM 6001 142880-36-2 1mg $75.2 2018-11-20 Buy
Sigma-Aldrich 364205 GM 6001 142880-36-2 5mg $271 2018-11-20 Buy
Alfa Aesar J65687 GM 6001 142880-36-2 5mg $305 2018-11-13 Buy
Alfa Aesar J65687 GM 6001 142880-36-2 1mg $84.8 2018-11-13 Buy
Cayman Chemical 14533 GM 6001 ≥90% 142880-36-2 500μg $25 2018-11-19 Buy

Ilomastat Chemical Properties,Uses,Production

Uses

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs). It inhibits zinc-containing thermolysin and elastase from P. aeruginosa, both with Ki values of 20 nM. GM 6001 inhibits MMP-1, -2, -7, -8, -9, -12, -13, -14, -16, and -26 with Ki or IC50 values between 0.1 and 10 nM. It inhibits disintegrin and metalloproteinase domain-containing (ADAM) proteins ADAM9, ADAM10, ADAM12, and ADAM17 at nanomolar concentrations. It less potently inhibits lethal factor from B. anthracis anthrax lethal toxin (Ki = 2.74 μM). GM 6001 also impairs the growth of the human pathogen Chlamydia by inhibiting peptide deformylase, which contains iron rather than zinc (IC50 = 38 nM).

Ilomastat Preparation Products And Raw materials

Raw materials

Preparation Products


Ilomastat Suppliers

Global( 69)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
0086-411-39042497
0086-411-39042693 sales@alphabiopharm.com China 1954 58
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2097 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14293 60
Shanghai XunTang Chemical Technology Co., Ltd. 15900811974/qq546264981
- 546264981@qq.com China 116 58
Shanghai Boyle Chemical Co., Ltd.
86-21-57758967 sales@boylechem.com China 2928 55
Alabiochem Tech.Co., Ltd. 0086-512-58900862; 400-0707-518; 0086-512-56727736
0086-512-56765862 sales@alabiochem.com China 944 59
VDM Biochemicals 0330-2528181
0330-2528171 sales@vdmbio.com United States 511 64
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1954 70
Chemsky(shanghai)International Co.,Ltd. 18964648857
shchemsky@163.com China 300 58
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811783;
+86 (531) 55696010 QQ 1762738062 sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) China 1858 62

142880-36-2(Ilomastat)Related Search:


  • (2R)-N4-Hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-butanediamide Ilomastat (GM6001, Galardin)
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  • Ilomastat, >=98%
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