2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
- CAS No.
- 4065-45-6
- Chemical Name:
- 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
- Synonyms
- BENZOPHENONE-4;BP-4;SULISOBENZONE;uvinul;UV-284;HMBS;5-BENZOYL-4-HYDROXY-2-METHOXYBENZENESULFONIC ACID;BIP1;2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULPHONIC ACID;ms40
- CBNumber:
- CB1359279
- Molecular Formula:
- C14H12O6S
- Molecular Weight:
- 308.31
- MDL Number:
- MFCD00024962
- MOL File:
- 4065-45-6.mol
- MSDS File:
- SDS
Melting point | 170 °C |
---|---|
Boiling point | 0°C |
Density | 1.4574 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.5300 (estimate) |
Flash point | 0°C |
storage temp. | Inert atmosphere,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | -0.70±0.50(Predicted) |
form | Solid |
color | White to Off-White |
Water Solubility | 300.92g/L at 25℃ |
Merck | 14,8983 |
BRN | 2889165 |
InChIKey | CXVGEDCSTKKODG-UHFFFAOYSA-N |
LogP | 0.515 at 25℃ |
CAS DataBase Reference | 4065-45-6(CAS DataBase Reference) |
EWG's Food Scores | 3 |
FDA UNII | 1W6L629B4K |
EPA Substance Registry System | Sulisobenzone (4065-45-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H412 | |||||||||
Precautionary statements | P264-P273-P280-P302+P352-P305+P351+P338-P332+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39-36/37/39-27 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | DB5044300 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29147000 | |||||||||
NFPA 704 |
|
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 1642100 | Sulisobenzone United States Pharmacopeia (USP) Reference Standard | 4065-45-6 | 500mg | $483 | 2024-03-01 | Buy |
Sigma-Aldrich | 09649 | 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid ≥97.0% (HPLC) | 4065-45-6 | 10g | $114 | 2024-03-01 | Buy |
TCI Chemical | H0466 | 2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid Hydrate(contains 5-10% Isopropyl Alcohol) >98.0%(T) | 4065-45-6 | 25g | $49 | 2024-03-01 | Buy |
TCI Chemical | H0466 | 2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid Hydrate(contains 5-10% Isopropyl Alcohol) >98.0%(T) | 4065-45-6 | 500g | $334 | 2024-03-01 | Buy |
Alfa Aesar | L12912 | 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid hydrate, tech. 85%, may cont. up to 10% 2-propanol | 4065-45-6 | 10g | $66.65 | 2024-03-01 | Buy |
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Chemical Properties,Uses,Production
Chemical Properties
white to yellowish powder
Originator
Uval,Dome,US,1965
Uses
sulisobenzone is the drug name for benzophenone-4, a sunscreen chemical.
Uses
Ultraviolet absorber for leather and textile fibers; in cosmetics and shampoos.
Uses
ultraviolet screen
Uses
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid is a commonly used, FDA approved sunscreen chemical with uVA-absorbing properties and an approved usage level of 5 to 10 percent. It protects a formulation from the effects of uV-light exposure.
Definition
ChEBI: Sulisobenzone is a member of benzophenones.
Manufacturing Process
663 g of dichloroethane and 74.6 g 2-hydroxy-4-methoxybenzophenone were charged into a 3-neck flask equipped with stirrer, thermometer, reflux condenser and dropping funnel and a heating mantle. The solution was heated to the reflux temperature (85°C to 86°C) and was dehydrated by distilling off 66.5 g 1,2-dichloroethane. While maintaining at reflux, 30 g chlorosulfonic acid was added slowly over a period of about two hours. The rate of addition was regulated by the speed of evolution of the HCl. After all the chlorosulfonic acid was added, the charge was still maintained at reflux for an additional 15 minutes to remove traces of HCl. It was then cooled to 5°C and filtered. The filter cake was washed with 500 g cold 1,2-dichloroethane and dried. 98 g of product were obtained.
brand name
Sungard (Bayer).
Therapeutic Function
Sunscreen agent
General Description
Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.
Flammability and Explosibility
Non flammable
Contact allergens
BZP-4 is widely used in cosmetics, particularly shampoos and hair products. Cross-reactivity is rarely expected in patients photoallergic to ketoprofen.
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Qingdao Truelight functional Material Technology Co., Ltd. | +86-13573844393 | songjames@truelightchem.com | China | 221 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD | +86 13658692156 | zandrew@jadenmtc.com | China | 222 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
Wuhan Fortuna Chemical Co.,Ltd | +8618007136271 | hk@fortunachem.com | China | 5964 | 58 |
Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3003 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3878 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5866 | 58 |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1090 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
View Lastest Price from 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-19 | Suncreen Agent UV 284
4065-45-6
|
US $100.00-80.00 / KG | 10KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-19 | 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
4065-45-6
|
US $3.50 / kg | 1kg | ≥99% | 3000tons/month | Hebei Andu Technology Com.,Ltd | ||
2024-09-19 | 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
4065-45-6
|
US $0.00-0.00 / kg | 0.10000000149011612kg | ≥99% | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
- Suncreen Agent UV 284
4065-45-6
- US $100.00-80.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
4065-45-6
- US $3.50 / kg
- ≥99%
- Hebei Andu Technology Com.,Ltd
- 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
4065-45-6
- US $0.00-0.00 / kg
- ≥99%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.