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Tribenoside

Tribenoside structure

CAS No.: 10310-32-4

Chemical Name:: Tribenoside

Synonyms: TBGF;Venex;Alven;21401-Ba;Glyvenol;Glyvenal;Glivenol;Tohcuron;Ba 21401;Flebosan

CBNumber:: CB1842212

Molecular Formula:: C29H34O6

Molecular Weight:: 478.58

MDL Number:: MFCD00801089

MOL File:: 10310-32-4.mol

MSDS File:: SDS

Last updated:2023-09-21 18:22:39

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Tribenoside Properties

alpha	D26 +8° (chloroform)
Boiling point	bp1.2 270-280°
Density	1.19±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Practically insoluble in water, very soluble in acetone, in methanol and in methylene chloride.
pka	13.01±0.70(Predicted)
color	Pale Yellow to Light Yellow
InChIKey	ULLNJSBQMBKOJH-VIVFLBMVSA-N
CAS DataBase Reference	10310-32-4
FDA UNII	Z7N0Y673NU
ATC code	C05AX05,C05CX01

SAFETY

Risk and Safety Statements

Hazard statements	H411
Toxicity	LD50 oral in rat: > 20gm/kg

Tribenoside price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0000165	Tribenoside European Pharmacopoeia (EP) Reference Standard	10310-32-4	y0000165	$220	2024-03-01	Buy
Usbiological	293301	Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside	10310-32-4	5g	$382	2021-12-16	Buy
Medical Isotopes, Inc.	O106695	Ethyl3-5-6-tri-O-benzyl-D-glucofuranoside	10310-32-4	5G	$395	2021-12-16	Buy
Biosynth Carbosynth	ME02540	Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside	10310-32-4	50g	$425	2021-12-16	Buy
Biosynth Carbosynth	ME02540	Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside	10310-32-4	100g	$750	2021-12-16	Buy

Product number	Packaging	Price	Buy
Y0000165	y0000165	$220	Buy
293301	5g	$382	Buy
O106695	5G	$395	Buy
ME02540	50g	$425	Buy
ME02540	100g	$750	Buy

Tribenoside Chemical Properties,Uses,Production

Chemical Properties

Yellowish to pale yellow, clear, viscous liquid.

Originator

Glyvenol,Ciba,W. Germany,1967

Uses

Sclerosing agent.

Uses

Tribenoside is a vasoprotective drug. It’s used in the treatment of hemorrhoids as it has mild anti-inflammatory and wound healing properties.

Definition

ChEBI: (3R,4R,5R)-5-[(1R)-1,2-bis(phenylmethoxy)ethyl]-2-ethoxy-4-phenylmethoxy-3-oxolanol is a glycoside.

Manufacturing Process

4.9 g of 3,5,6-tribenzyl-1,2-isopropylidene glucofuranose are kept overnight at room temperature with 100 cc of N-ethanolic hydrochloric acid. Evaporation under vacuum at below 50°C is then carried out and the residue taken up in 150 cc of chloroform. The chloroform solution is thoroughly washed with sodium bicarbonate solution, dried with calcined sodium sulfate and evaporated under vacuum. The oily residue is then distilled under vacuum with a free flame. In this manner there is obtained the ethyl-3,5,6-tribenzyl_x0002_D-glucofuranoside of boiling point 270°C to 275°C under 1 mm pressure. The glucofuranose used as starting material is obtained as follows: 8.8 g of 1,2-isopropylidene-D-glucofuranose and 50.6 g of benzyl chloride are treated with a total of 28 g of potassium hydroxide in portions with cooling and stirring. The mixture is then stirred for 3 hours at 80°C to 90°C. Working up from chloroform solution and distillation at 250°C to 260°C under 0.1 mm pressure give 8.9 g of 1,2-isopropylidene-3,5,6-tribenzyl-D-glucofuranose.

Therapeutic Function

Topical venotonic

Hazard

Low toxicity by ingestion.

Contact allergens

This drug is used for the treatment, both topical and oral, of hemorrhoids. It leads to benzo?c acid, that is contained in Myroxylon pereirae as well, and could be the sensitizer.

Tribenoside Preparation Products And Raw materials

Raw materials

Benzyl chloride

Preparation Products

Tribenoside Suppliers

Global( 126)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	6011	58
shandong perfect biotechnology co.ltd	+86-53169958659; +8618596095638	sales@sdperfect.com	China	294	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	985	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15956	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10247	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	7019	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
shandong perfect biotechnology co.ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
BOC Sciences	58

View Lastest Price from Tribenoside manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-12	Tribenoside 10310-32-4	US $0.00-0.00 / KG	1KG	98% HPLC	1000kg	shandong perfect biotechnology co.ltd
2023-11-01	Tribenoside 10310-32-4	US $0.00 / kg	1kg	99.0%min	10000kg	Hangzhou ICH Biofarm Co., Ltd
2023-09-20	Tribenoside 10310-32-4	US $100.00 / kgkg	1kgkg	0.99	100	Hebei Yanxi Chemical Co., Ltd.

Tribenoside
10310-32-4
US $0.00-0.00 / KG
98% HPLC
shandong perfect biotechnology co.ltd

Tribenoside
10310-32-4
US $0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

Tribenoside
10310-32-4
US $100.00 / kgkg
0.99
Hebei Yanxi Chemical Co., Ltd.

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Glivenol Glucofuranoside, ethyl 3,5,6-tri-O-benzyl- (7CI) Glucofuranoside, ethyl 3,5,6-tri-O-benzyl-, D- (8CI) Glyvenal Glyvenol Hemocuron TBGF Tribenzoside Venex 1-O-Ethyl-3-O,5-O,6-O-tribenzyl-D-glucofuranose 21401-Ba Tohcuron (3R,4R,5R)-4-(Benzyloxy)-5-((R)-1,2-bis(benzyloxy)ethyl)-2-ethoxytetrahydrofuran-3-ol D-Glucofuranoside,ethyl 3,5,6-tris-O-(phenylMethyl)- -1,2-bis(benzyloxy) -2-ethoxytetrahydrofuran-3-ol (3R,4R,5R)-5-[1,2-Bis(phenylmethoxy)ethyl]-2-ethoxy-4-(phenylmethoxy)oxolan-3-ol ETHYL-3,5,6-TRI-O-BENZYL-D-GLUCOFURANOSIDE Alven Ba 21401 D-Glucofuranoside, ethyl 3,5,6-tris-O-(phenylmethyl)- (9CI) Flebosan TRIBENOSIDE (3R,4R,5R)-4-(benzyloxy)-5-[(1R)-1,2-bis(benzyloxy)ethyl]-2-ethoxyoxolan-3-ol Tribenoside (3R,4R,5R)-5-[1,2-Bis(phenylmethoxy)ethyl]-2-ethoxy-4-(phenylmethoxy)oxolan-3-ol Tribenoside CRS Tribenoside API Tribenzyl glycoside 10310-32-4 C29H34O6