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2-Ethoxyethanol structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

2-Ethoxyethanol Properties

Melting point:
-100 °C
Boiling point:
135 °C(lit.)
0.93 g/mL at 25 °C(lit.)
vapor density 
3.1 (vs air)
vapor pressure 
3.8 mm Hg ( 20 °C)
refractive index 
n20/D 1.407(lit.)
Flash point:
107.6 °F
storage temp. 
Flammables area
water: miscible
Clear, colorless
Sweetish; mild, pleasant, ethereal.
explosive limit
Water Solubility 
λ: 215 nm Amax: 1.00
λ: 225 nm Amax: 0.50
λ: 250 nm Amax: 0.20
λ: 305 nm Amax: 0.01
Exposure limits
TLV-TWA skin 5 ppm (18.5 mg/m3) (ACGIH). .
Stable. Readily forms explosive mixtures with air - note the wide explosion range. Vapour may travel considerable distance to a source of ignition. Flammable. Incompatible with strong acids, strong bases, strong oxidizing agents, aluminium, alkalies.
CAS DataBase Reference
110-80-5(CAS DataBase Reference)
NIST Chemistry Reference
Ethanol, 2-ethoxy-(110-80-5)
EPA Substance Registry System
Ethanol, 2-ethoxy-(110-80-5)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  T
Risk Statements  60-61-10-20/21/22-20/22
Safety Statements  53-45
RIDADR  UN 1171 3/PG 3
WGK Germany  1
RTECS  KK8050000
Autoignition Temperature 460 °F
HazardClass  3
PackingGroup  III
HS Code  29094990
Hazardous Substances Data 110-80-5(Hazardous Substances Data)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.

NFPA 704

Diamond Hazard Value Description
2 0
Health   2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
Flammability   2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

2-Ethoxyethanol price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 128082 2-Ethoxyethanol ReagentPlus , 99% 110-80-5 1l $51.3 2018-11-13 Buy
Sigma-Aldrich 128082 2-Ethoxyethanol ReagentPlus , 99% 110-80-5 4l $183 2018-11-13 Buy
TCI Chemical E0047 2-Ethoxyethanol >99.0%(GC) 110-80-5 25mL $16 2018-11-22 Buy
TCI Chemical E0047 2-Ethoxyethanol >99.0%(GC) 110-80-5 500mL $23 2018-11-22 Buy
Alfa Aesar A16100 2-Ethoxyethanol, 99% 110-80-5 500ml $24.2 2018-11-15 Buy

2-Ethoxyethanol Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Chemical Properties

2-Ethoxyethanol is a colorless, viscous liquid with a sweetish odor

Chemical Properties

Ethylene glycol monoethyl ether is a colorless liquid with a sweet, mild odor and slightly bitter taste. It is miscible in all proportions of acetone, benzene, carbon tetrachloride, ethyl ether, methanol, and water. It dissolves many oils, resins, and waxes.


Ethylene glycol monoethyl ether is used in varnish removers, lacquers, and as a solvent for printing inks, duplicating fluids, and epoxy. Ethylene glycol monobutyl ether is used in hydraulic fluids, as a coupling agent for water-based coatings, in vinyl and acrylic paints and varnishes, and as a solvent for varnishes, enamels, spray lacquers, dry cleaning compounds, textiles, and cosmetics.


antiobesity agent pancreatic lipase inhibitor


Ethylene glycol monoethyl ether (EGEE) isused as a solvent for nitrocellulose, lacquers,and varnishes; in dye baths and cleansingsolutions; and as an emulsion stabilizer.


ChEBI: A hydroxyether that is the ethyl ether derivative of ethylene glycol.

General Description

A clear colorless liquid. Flash point of 120°F. Less dense than water. Its vapors are heavier than air.

Air & Water Reactions

Flammable. Water soluble.

Reactivity Profile

ETHYLENE GLYCOL MONOMETHYL ETHER may react with oxidizing materials, i.e. hydrogen peroxide, to form peroxides. 2-Ethoxyethanol dissolves many oils, resins and waxes.


Toxic by skin absorption. Moderate fire risk.

Health Hazard

Some eye irritation. Inhalation of vapors causes irritation of nose.

Health Hazard

EGEE is a teratogen and at high concentration a toxic substance. The target organs arethe lungs, kidney, liver, and spleen. Animalexperiments indicated that inhalation of itsvapors at 2000 ppm for several hours couldproduce toxic effect. Death resulted from kid ney injury when the test species were sub jected to a 24-hour exposure. It producedkidney injury, hematuria, and microscopiclesions of both the liver and kidney. EGEEmay be absorbed through the skin. Wheninserted into the eyes, it produced corneal irritation. The recovery occurred within 24 hours
Investigating the subchronic inhalationtoxicology of EGEE in the rat and rabbit,Barbee et al. (1984) reported no biologicalsignificant effect of this compound in theseanimals at an exposure level of 400 and100 ppm, respectively. Chronic treatment ofrats with EGEE at 0.5–1.0 g/kg in an oraldose caused enlargement of adrenal gland inmale rats and affected the development ofspontaneous lesions of the spleen (males andfemales), pituitary (males and females), andLD50 value(rats):3000 mg/kg(NIOSH1986)testis (males) (Melnick 1984).
LC50 value (mice): 1820 ppm/7 hr (NIOSH 1986)
In humans there is no report of any severe poisoning case. The toxic effect from inhaling its vapors at 1000 ppm may be less than noticeable. EGEE is less toxic than EGME. Whenadministeredorallyto youngmale rats, EGEE produced testicular atrophy similar to that of EGME (Nagano et al. 1984). However, a fivefold dose, 250–1000 mg/kg/day, was required to elicit equivalent severity (Foster et al. 1984)
Reproductive toxicity of EGEE has been investigated extensively (Lamb et al. 1984; Hardin et al. 1984; Oudiz et al. 1984). Testicular atrophy, decline in sperm count, and increased abnormal sperm were observed in treated male rats, but no specific anomalies were noted in the females. Wier et al. (1987) investigated postnatal growth and survival. EGEE produced embryo lethality and malformations and decreased fetal weight. Prenatal exposure to EGEE produced kinked tails in pups. Ethanol caused potentiation of reproductive toxicity of EGEE (Nelson et al. 1984).

Fire Hazard

Flash Point (°F): 120 ℃; 202 ℃; Flammable Limits in Air (%): 1.8-14,0; Fire Extinguishing Agents: Alcohol foam, carbon dioxide, or dry chemical; Fire Extinguishing Agents Not To Be Used: Not pertinent; Special Hazards of Combustion Products: Not pertinent; Behavior in Fire: Not pertinent; Ignition Temperature (°F): 455; Electrical Hazard: Not pertinent; Burning Rate: 2.4 mm/min.

Fire Hazard

Special Hazards of Combustion Products: Toxic gases, such as carbon monoxide, may be produced in fire.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

Moderately toxic by ingestion, skin contact, intravenous, and intraperitoneal routes. Mildly toxic by inhalation and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. A mild eye and skin irritant. Combustible when exposed to heat or flame; can react with oxidzing materials. Moderate explosion hazard in the form of vapor when exposed to heat or flame. Mxture with hydrogen peroxide + polyacrylamide gel + toluene is explosive when dry. To fight fire, use alcohol foam, dry chemical. See also GLYCOL ETHERS.

Potential Exposure

This material is used as a solvent for nitrocellulose and alkyd resins in lacquers; as a solvent for printing inks; in dyeing leathers and textiles; in the formulation of cleaners and varnish removers; as an anti-icing additive in brake fluids and auto and aviation fuels.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Keep victim under medical observation


UN1171 Ethylene glycol monoethyl ether, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Dry it with CaSO4 or K2CO3, filter and fractionally distil it. Peroxides can be removed by refluxing with anhydrous SnCl2 or by filtration under slight pressure through a column of activated alumina. [Beilstein 1 IV 2377.]


May form explosive mixture with air. Strong oxidizers may cause fire and explosions. Attacks some plastics, rubber and coatings. Able to form peroxides. Incompatible with strong acids; aluminum and its alloys

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≧100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal

2-Ethoxyethanol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Ethoxyethanol Suppliers

Global( 251)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32606 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1747 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6402 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24093 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20177 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4696 58
career henan chemical co
+86-371-86658258 CHINA 19975 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 China 25086 65
Nanjing Apicci Pharmaceutical Technology Co., Ltd. 18061682508,QQ3590429773;18014482516,QQ 977144864
025-52184842 China 287 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76

View Lastest Price from 2-Ethoxyethanol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-05 2-Ethoxyethanol Factory
US $1.00 / kg 1kg Heavy metal < 1-10 ppb High quality Factory Chemwill Asia Co.,Ltd.
2018-12-18 2-Ethoxyethanol
US $1.00 / kg 1kg as customer's need 500kg career henan chemical co

2-Ethoxyethanol Spectrum

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