ChemicalBook
Chinese Japanese Germany Korea

4-Methoxyphenol

4-Methoxyphenol
4-Methoxyphenol structure
CAS No.
150-76-5
Chemical Name:
4-Methoxyphenol
Synonyms
PMF;1OP;MEHQ;MQ-F;HQMM;Hqmme;usafan-7;MEQUINOL;NSC 4960;USAF an-7
CBNumber:
CB7853133
Molecular Formula:
C7H8O2
Formula Weight:
124.14
MOL File:
150-76-5.mol

4-Methoxyphenol Properties

Melting point:
56 °C
Boiling point:
243 °C(lit.)
Density 
1,55 g/cm3
vapor density 
4.3 (vs air)
vapor pressure 
<0.01 mm Hg ( 20 °C)
refractive index 
1.5286 (estimate)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
Soluble in acetone, ethyl acetate, ethanol, ether, benzene and carbon tetrachloride.
form 
Liquid
pka
10.21(at 25℃)
color 
Clear colorless to pale yellow
PH
5.1 (30g/l, H2O, 20℃)
Odor Threshold
0.0027ppm
Water Solubility 
40 g/L (25 ºC)
BRN 
507924
Stability:
Stable. Combustible. Incompatible with halogens, oxidizing agents.
InChIKey
NWVVVBRKAWDGAB-UHFFFAOYSA-N
CAS DataBase Reference
150-76-5(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances
4-METHOXYPHENOL
FDA 21 CFR
177.1010
EWG's Food Scores
4-7
FDA UNII
6HT8U7K3AM
ATC code
D11AX06
NIST Chemistry Reference
Mequinol(150-76-5)
EPA Substance Registry System
p-Methoxyphenol (150-76-5)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H402-H302-H317-H319-H361d-H412
Precautionary statements  P201-P273-P280-P308+P313-P333+P313-P337+P313-P261-P264-P270-P272-P301+P312+P330-P302+P352+P333+P313+P363-P305+P351+P338+P337+P313-P501-P262-P280a-P301+P310-P305+P351+P338-P315
Hazard Codes  Xn
Risk Statements  22-36-43
Safety Statements  24/25-26-37/39-46
WGK Germany  1
RTECS  SL7700000
Autoignition Temperature 789 °F
TSCA  Yes
HS Code  29095090
Toxicity LD50 orally in Rabbit: 1600 mg/kg
NFPA 704
1
2 0

4-Methoxyphenol price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.21233 4-Methoxyphenol for synthesis 150-76-5 5 g $17.2 2021-03-22 Buy
Sigma-Aldrich 8.21233 4-Methoxyphenol for synthesis 150-76-5 25 g $22.01 2021-03-22 Buy
Sigma-Aldrich 54050 4-Methoxyphenol purum, ≥98.0% (HPLC) 150-76-5 100g $31.4 2021-03-22 Buy
Sigma-Aldrich 8.21233 4-Methoxyphenol for synthesis 150-76-5 250 g $39.5 2021-03-22 Buy
Sigma-Aldrich 54050 4-Methoxyphenol purum, ≥98.0% (HPLC) 150-76-5 500g $63.2 2021-03-22 Buy

4-Methoxyphenol Chemical Properties,Uses,Production

Chemical Properties

4-Methoxyphenol is a colorless to white, waxy solid with an odor of caramel and phenol. A combustible solid.

Uses

Inhibitor for acrylic monomers; stabilizer for chlorinated hydrocarbons and ethyl cellulose; UV inhibitor

Uses

4-Methoxyphenol is an active ingredient and used in dermatology. It is employed as a pharmaceutical drug in skin depigmentation. It is used as polymerization inhibitors. For example, in the radical polymerization of acryaltes and styrene monomers. It is also used as an intermediate in the preparationagrochemicals, liquid crystals. It acts as a stabilizer for the formulation of inks, toners and adhesives. It is mainly used as an additive for textile and leather industries.

Uses

Intermediates of Liquid Crystals.
4-methoxyphenol may be used in the synthesis of butylated hydroxy anisoles via alkylation with methyl tert-butyl ether over a non-zeolitic solid acidic catalyst. This process is eco-friendly when compared to the Friedel-Crafts alkylation reaction. 4-MP may also react with aqueous nitrous acid to form 2-nitro-4-methoxyphenol and benzoquinone in varying ratios depending on the reaction conditions. 4-MP can be used as a building block in designing β-cyclodextrin 4-methoxyphenol conjugates that can be potential ligands for drug complexation.

Indications

Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts as a competitive inhibitor of melanogenesis.

Synthesis Reference(s)

The Journal of Organic Chemistry, 42, p. 1479, 1977 DOI: 10.1021/jo00428a054
Synthesis, p. 751, 1983 DOI: 10.1055/s-1983-30501
Tetrahedron Letters, 34, p. 7667, 1993 DOI: 10.1016/S0040-4039(00)61534-4

General Description

Pink crystals or white waxy solid.

Air & Water Reactions

Sensitive to moisture. Water soluble.

Reactivity Profile

4-Methoxyphenol can react with oxidizing materials.

Hazard

Eye irritant and skin damage.

Health Hazard

4-Methoxyphenol is expected to cause liver and renal toxicity with narcosis, but only at high levels of exposure.

Fire Hazard

Combustible

Safety Profile

Poison by intraperitoneal route. A skin irritant. When heated to decomposition it emits acrid smoke and fumes. See also ETHERS.

Shipping

UN3335 Aviation regulated solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Crystallise 4-methoxyphenol from *benzene, pet ether or H2O, and dry it under vacuum over P2O5 at room temperature. Sublime it in vacuo. [Wolfenden et al. J Am Chem Soc 109 463 1987, Beilstein 6 IV 5717.]

4-Methoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products


4-Methoxyphenol Suppliers

Global( 591)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Jinan Finer Chemical Co., Ltd
+8615508631887 +86-531-88989536
+86-531-88989539 sales@finerchem.com CHINA 1716 58
Yancheng Green Chemicals Co.,Ltd
86-25-86655873
86-25-52279193 sales@greenchem-china.com CHINA 93 58
Foshan Sanshui Jingze Chemical Co.,Ltd
025-86639253
025-52279193 sales@jingze-chem.com CHINA 54 58
Hebei Yanxi Chemical Co., Ltd.
+8618633081222
peter@yan-xi.com CHINA 692 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20892 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8910 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Anhui Royal Chemical Co., Ltd.
+86-025-86655873
marketing@royal-chem.com CHINA 536 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55

Related articles


View Lastest Price from 4-Methoxyphenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-08 p-Hydroxyanisole (MEHQ)
150-76-5
US $0.00 / kg 1kg 99% 500mt Jinan Finer Chemical Co., Ltd
2021-12-01 Mequinol
150-76-5
US $8.00 / Kg/Bag 10g 99% 10000kg Hebei Crovell Biotech Co Ltd
2021-11-29 4-Methoxyphenol
150-76-5
US $0.00 / KG 1KG 99% 20ton Wuhan Dujiang Industrial Co., Ltd.

4-Methoxyphenol Spectrum


150-76-5(4-Methoxyphenol)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved