chlorproethazine

chlorproethazine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Originator

Neuriplege, Genevrier ,France,1961

Uses

MIchlorproethazine.

Manufacturing Process

2-Bromo-2'-(3''-dimethylaminopropyl)-amino-4'-chlorodiphenylsulfide (10 g) is dissolved in dimethylformamide (80 cc). To this solution is added potassium carbonate (5 g) and copper powder (0.4 g). It is then heated under reflux for 48 hours, cooled, and the insoluble matter filtered off. After washing with dimethylformamide (20 cc), the filtrate is taken up in distilled water (200cc). The base formed is extracted with ether (3 times with 50 cc), the ethereal solution is dried over sodium sulfate, the ether driven off on a water-bath and the residue distilled. In this way there is obtained 3-chloro-10-(3'- dimethylaminopropyl)-phenothiazine (6.4 g) which boils at 210 C to 225°C under 0.7 mm of mercury. The hydrochloride is made by the action of ethereal hydrogen chloride on the base dissolved in acetone; this hydrochloride melts at 180°C

Therapeutic Function

Muscle relaxant; Tranquilizer

chlorproethazine Preparation Products And Raw materials

Raw materials

Preparation Products

chlorproethazine Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Toronto Research Chemicals	--	--	info@trc-canada.com	Canada	6113	71
Service Chemical Inc.	--	--	sales@chemos-group.com	Germany	6483	71

84-01-5(chlorproethazine )Related Search:

---

• chlorproethazine
• 3-(2-chlorophenothiazin-10-yl)-N,N-diethylpropan-1-amine
• CHLOROPROETHAZINE
• 2-CHLORO-10-(3-(DIETHYLAMINO)PROPYL)PHENOTHIAZINE
• 2-Chloro-10-(3-diethylaminopropyl)-10H-phenothiazine
• 2-Chloro-N,N-diethyl-10H-phenothiazine-10-propan-1-amine
• Neuriplege
• RP-4909
• 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-diethyl-
• 84-01-5
• C19H14D10Cl2N2S
• Amines
• Aromatics
• Heterocycles
• Intermediates & Fine Chemicals
• Isotope Labelled Compounds
• Pharmaceuticals
• Sulfur & Selenium Compounds