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chlorproethazine

chlorproethazine
chlorproethazine structure
CAS No.
84-01-5
Chemical Name:
chlorproethazine
Synonyms
RP-4909;Neuriplege;chlorproethazine;CHLOROPROETHAZINE;2-CHLORO-10-(3-(DIETHYLAMINO)PROPYL)PHENOTHIAZINE;2-Chloro-10-(3-diethylaminopropyl)-10H-phenothiazine;10H-Phenothiazine-10-propanamine, 2-chloro-N,N-diethyl-;2-Chloro-N,N-diethyl-10H-phenothiazine-10-propan-1-amine;3-(2-chlorophenothiazin-10-yl)-N,N-diethylpropan-1-amine
CBNumber:
CB1939080
Molecular Formula:
C19H23ClN2S
Formula Weight:
346.92
MOL File:
84-01-5.mol

chlorproethazine Properties

Melting point:
153-156°C
Boiling point:
211°C (rough estimate)
Density 
1.1206 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
-20?C Freezer
FDA UNII
960NX27Z07

chlorproethazine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Originator

Neuriplege, Genevrier ,France,1961

Uses

MIchlorproethazine.

Manufacturing Process

2-Bromo-2'-(3''-dimethylaminopropyl)-amino-4'-chlorodiphenylsulfide (10 g) is dissolved in dimethylformamide (80 cc). To this solution is added potassium carbonate (5 g) and copper powder (0.4 g). It is then heated under reflux for 48 hours, cooled, and the insoluble matter filtered off. After washing with dimethylformamide (20 cc), the filtrate is taken up in distilled water (200cc). The base formed is extracted with ether (3 times with 50 cc), the ethereal solution is dried over sodium sulfate, the ether driven off on a water-bath and the residue distilled. In this way there is obtained 3-chloro-10-(3'- dimethylaminopropyl)-phenothiazine (6.4 g) which boils at 210 C to 225°C under 0.7 mm of mercury. The hydrochloride is made by the action of ethereal hydrogen chloride on the base dissolved in acetone; this hydrochloride melts at 180°C

Therapeutic Function

Muscle relaxant; Tranquilizer

chlorproethazine Preparation Products And Raw materials

Raw materials

Preparation Products


chlorproethazine Suppliers

Global( 2)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Toronto Research Chemicals --
-- info@trc-canada.com Canada 6113 71
Service Chemical Inc. --
-- sales@chemos-group.com Germany 6483 71

84-01-5(chlorproethazine )Related Search:


  • chlorproethazine
  • 3-(2-chlorophenothiazin-10-yl)-N,N-diethylpropan-1-amine
  • CHLOROPROETHAZINE
  • 2-CHLORO-10-(3-(DIETHYLAMINO)PROPYL)PHENOTHIAZINE
  • 2-Chloro-10-(3-diethylaminopropyl)-10H-phenothiazine
  • 2-Chloro-N,N-diethyl-10H-phenothiazine-10-propan-1-amine
  • Neuriplege
  • RP-4909
  • 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-diethyl-
  • 84-01-5
  • C19H14D10Cl2N2S
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
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