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1-INDOLEPROPIONIC ACID

CAS No.
6639-06-1
Chemical Name:
1-INDOLEPROPIONIC ACID
Synonyms
1-INDOLEPROPIONIC ACID;Indole-1-propionic acid;B-N-INDOLEPROPIONIC ACID;1H-indole-1-propanoic acid;3-indol-1-ylpropionic acid;3-indol-1-ylpropanoic acid;3-(1-indolyl)propanoic acid;BETA-N-INDOLE PROPIONIC ACID;3-(1H-INDOL-1-YL)PROPANOIC ACID
CBNumber:
CB2379252
Molecular Formula:
C11H11NO2
Molecular Weight:
189.21
MDL Number:
MFCD00022896
MOL File:
6639-06-1.mol
MSDS File:
SDS
Last updated:2026-01-13 11:16:07
Product description Number Pack Size Price
1-INDOLEPROPIONIC ACID AldrichCPR S540390 1 unit $197
1-INDOLEPROPIONIC ACID AldrichCPR S540390 1G $179
3-(1H-Indol-1-yl)propanoicacid Z5006 10g $611
1-INDOLEPROPIONIC ACID 95.00% CHM0118689 1G $648.81
1-INDOLEPROPIONIC ACID 95.00% CHM0118689 2.5G $852.21

1-INDOLEPROPIONIC ACID Properties

Melting point 91 °C
Boiling point 180-197 °C
Density 1.19±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 4.59±0.10(Predicted)
FDA UNII HN7XR99LDF

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338-P310
HazardClass  IRRITANT
HS Code  2933998090

1-INDOLEPROPIONIC ACID price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S540390 1-INDOLEPROPIONIC ACID AldrichCPR 6639-06-1 1 unit $197 2026-03-19 Buy
Sigma-Aldrich S540390 1-INDOLEPROPIONIC ACID AldrichCPR 6639-06-1 1G $179 2024-03-01 Buy
AK Scientific Z5006 3-(1H-Indol-1-yl)propanoicacid 6639-06-1 10g $611 2021-12-16 Buy
American Custom Chemicals Corporation CHM0118689 1-INDOLEPROPIONIC ACID 95.00% 6639-06-1 1G $648.81 2021-12-16 Buy
American Custom Chemicals Corporation CHM0118689 1-INDOLEPROPIONIC ACID 95.00% 6639-06-1 2.5G $852.21 2021-12-16 Buy
Product number Packaging Price Buy
S540390 1 unit $197 Buy
S540390 1G $179 Buy
Z5006 10g $611 Buy
CHM0118689 1G $648.81 Buy
CHM0118689 2.5G $852.21 Buy

1-INDOLEPROPIONIC ACID Chemical Properties,Uses,Production

Synthesis

Indole

120-72-9

Methyl 3-bromopropionate

3395-91-3

1-INDOLEPROPIONIC ACID

6639-06-1

General procedure for the synthesis of 1-indolepropionic acid from indole and methyl 3-bromopropionate: Synthesis of 3-(1H-indol-1-yl)propionic acid (Intermediate-25): 10 mL of DMF was added to a 100 mL round bottom flask fitted with a magnetic stirrer. to the stirred solvent was added indole (1.0 g, 8.53 mmol) followed by sodium hydride (400 mg, 10.24 mmol). The resulting mixture was stirred at room temperature for 1 hr. Methyl 3-bromopropionate (2.13 g, 12.79 mmol) was added to the above reaction solution and stirring was continued for 24 hours at room temperature. After completion of the reaction (the progress of the reaction was monitored by TLC), the reaction mixture was diluted with 30 mL of ice water and washed with ether. The aqueous phase was acidified with 1N HCl to pH=2 and subsequently extracted with EtOAc and concentrated to give Intermediate-24 (900 mg).

References

[1] Patent: WO2013/128465, 2013, A1. Location in patent: Page/Page column 94
[2] Patent: US2015/158860, 2015, A1. Location in patent: Paragraph 0332
[3] Patent: WO2004/43899, 2004, A1. Location in patent: Page 37; 38

1-INDOLEPROPIONIC ACID Preparation Products And Raw materials

1-INDOLEPROPIONIC ACID Suppliers

Global( 55)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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Nantong Bosu Pharmaceutical Technology Co., Ltd. 15962844273 tashiyxy@163.com China 544 58
BETA-N-INDOLE PROPIONIC ACID B-N-INDOLEPROPIONIC ACID 3-(1H-INDOL-1-YL)PROPANOIC ACID 1-INDOLEPROPIONIC ACID 1H-indole-1-propanoic acid 3-(1-indolyl)propanoic acid 3-indol-1-ylpropanoic acid 3-indol-1-ylpropionic acid Indole-1-propionic acid 6639-06-1 6639-6-1 CARBOXYLIC ACID