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[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide structure

CAS No.: 27710-82-3

Chemical Name:: [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide

Synonyms: (3-DIMETHYLAMINOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE HYDROBROMIDE;orOlopatadine;forOlopatadine;[3-(Dimethylamino)pr;Olopatadine Impurity 8 HBr;Olopatadine Impurity 13 HBr;Olatadine Impurity 17(hydrobromide);(3-DIMETHYLAMINOPROPYL)-TRIPHENYL-PHOSPH;triphenylphosphoniuM broMide hydrobroMide;[3-(DiMethylaMino)propyl]triphenylphosphoniuM broM

CBNumber:: CB3135473

Molecular Formula:: C23H28Br2NP

Molecular Weight:: 509.27

MDL Number:: MFCD00077740

MOL File:: 27710-82-3.mol

MSDS File:: SDS

Last updated:2025-09-26 17:40:57

Product description	Number	Pack Size	Price
[3-(Dimethylamino)propyl]triphenylphosphoniumBromideHydrobromide	D495303	5g	$65
(3-(Dimethylamino)propyl)triphenyl-phosphonium bromide hydrobromide 95+%	097494	1g	$87
(3-Dimethylaminopropyl)triphenylphosphonium bromide hydrobromide	FD147012	50g	$105
[3-(Dimethylamino)propyl]triphenylphosphoniumbromidehydrobromide	N760	10g	$30
[3-(Dimethylamino)propyl]triphenylphosphoniumbromidehydrobromide	J52092	25g	$46
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[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide Properties

Melting point	283-285 °C
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	Off-White
Stability	Hygroscopic
InChI	InChI=1S/C23H27NP.2BrH/c1-24(2)19-12-20-25(21-13-6-3-7-14-21,22-15-8-4-9-16-22)23-17-10-5-11-18-23;;/h3-11,13-18H,12,19-20H2,1-2H3;2*1H/q+1;;/p-1
InChIKey	NEQVFHFOWYYPBS-UHFFFAOYSA-M
SMILES	[P+](C1C=CC=CC=1)(C1C=CC=CC=1)(C1C=CC=CC=1)CCCN(C)C.[Br-].Br
CAS DataBase Reference	27710-82-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H401-H227
Precautionary statements	P501-P273-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	3-10

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D495303	[3-(Dimethylamino)propyl]triphenylphosphoniumBromideHydrobromide	27710-82-3	5g	$65	2021-12-16	Buy
Matrix Scientific	097494	(3-(Dimethylamino)propyl)triphenyl-phosphonium bromide hydrobromide 95+%	27710-82-3	1g	$87	2021-12-16	Buy
Biosynth Carbosynth	FD147012	(3-Dimethylaminopropyl)triphenylphosphonium bromide hydrobromide	27710-82-3	50g	$105	2021-12-16	Buy
AK Scientific	N760	[3-(Dimethylamino)propyl]triphenylphosphoniumbromidehydrobromide	27710-82-3	10g	$30	2021-12-16	Buy
AK Scientific	J52092	[3-(Dimethylamino)propyl]triphenylphosphoniumbromidehydrobromide	27710-82-3	25g	$46	2021-12-16	Buy

Product number	Packaging	Price	Buy
D495303	5g	$65	Buy
097494	1g	$87	Buy
FD147012	50g	$105	Buy
N760	10g	$30	Buy
J52092	25g	$46	Buy

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide Chemical Properties,Uses,Production

Uses

(3-(Dimethylamino)propyl)triphenylphosphonium bromide is used as a reactant for preparing chlorpheniramine analogs reverse chloroquine resistance in Plasmodium falciparum by inhibiting PfCRT.

Synthesis

(3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE

3607-17-8

124-40-3

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide

27710-82-3

To a suspension of (3-bromopropyl)triphenylphosphonium bromide (1.0 g, 2.1 mmol) in ethanol (5 mL) was slowly added 40% aqueous dimethylamine (3 mL) at room temperature. The reaction mixture was transferred to a sealed microwave reaction tube and heated at 100 °C with stirring for 30 min. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by recrystallization in acetonitrile to afford [3-(dimethylamino)propyl]triphenylphosphonium bromide hydrobromide (0.90 g, 82% yield) as a white solid, which was used directly in the subsequent reaction.ESI MS m/z 348.3 (corresponding to Ph3PCH2CH2CH2CH2NMe2+ ions).

References

[1] Patent: WO2012/79017, 2012, A1. Location in patent: Page/Page column 68
[2] Patent: US2007/232814, 2007, A1. Location in patent: Page/Page column 24

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide synthesis

Synthesis of [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide from (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE and Dimethylamine

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide Preparation Products And Raw materials

Raw materials

(3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Dimethylamine

Preparation Products

Olopatadine Olopatadine hydrochloride (E)-Olopatadine Hydrochloride

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide Suppliers

Global( 234)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Anhui Royal Chemical Co., Ltd.	+86-025-86655873 +8613962173137	marketing@royal-chem.com	China	199	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Changzhou Rokechem Technology Co., Ltd.	18758118018	sales001@rokechem.com	China	255	58
Anhui Dexinjia Biopharm Co., Ltd	+86-531-82375818 +86-15064153060	sales01@jndxj.com	China	301	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8768	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21614	55

Supplier	Advantage
Anhui Royal Chemical Co., Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
Changzhou Rokechem Technology Co., Ltd.	58
Anhui Dexinjia Biopharm Co., Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-03	[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide 27710-82-3	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-11-28	[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide 7710-82-3	US $0.00-0.00 / kg	0.001kg	99.99%	200000T	Anhuyan (Hainan) Biotechnology Co., LTD
2025-11-18	[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide 27710-82-3	US $1.10 / g	1g	99.0% Min	100 Tons	Dideu Industries Group Limited

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide
27710-82-3
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide
7710-82-3
US $0.00-0.00 / kg
99.99%
Anhuyan (Hainan) Biotechnology Co., LTD

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide
27710-82-3
US $1.10 / g
99.0% Min
Dideu Industries Group Limited

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide Spectrum

[3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide(27710-82-3)¹HNMR

27710-82-3([3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide)Related Search:

Scopolamine hydrobromide Sodium bromate Clidinium bromide Hydrogen bromide Propyl gallate

(FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Propyl butyrate HYOSCINE N BUTYL BROMIDE BP Ethidium bromide DEXTROMETHORPHAN HYDROBROMIDE

Methyl bromide Olopatadine 3-((Dimethylamino)propyl)triphenylphosphonium bromide (3-AMINOPROPYL)DIPHENYLPHOSPHINE [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide

Bromide

1of4

(3-DIMETHYLAMINOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE HYDROBROMIDE 98% (3-DIMETHYLAMINOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE HBR [3-(Dimethylamino)pr [3-(DiMethylaMino)propyl]triphenylphosphoniuM broM triphenylphosphoniuM broMide hydrobroMide (3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide hydrobroMide puruM (3-diMethylaMinopropyl)triphenylphospho-niuM broMo hydrobroMide [3-(diMethylaMino)propyl]triphenylphosphaniuM hydrobroMide broMide [3-(Dimethylamino)propyl]triphenylphosphonium bromide Hcl orOlopatadine PHOSPHONIUM, [3-(DIMETHYLAMINO)PROPYL]TRIPHENYL BROMIDE HYDROBROMIDE (3-dimethylaminopropyl)triphenylphospho-nium brom.hydrobromi PHOSPHONIUM,[3-(DIMETHYLAMINO)PROPYL]TRIPHENYL BROMIDE HBr [3-(Dimethylamino)propyl]triphenyl bromide hydrobromide (3-DIMETHYLAMINOPROPYL)-TRIPHENYL-PHOSPH PHOSPHONIUM, [3-(DIMETHYLAMINO)PROPYL]TRIPHENYL BROMIDE HYDROBROMIDE (FOR OLOPATADINE) [3-(Dimethylamino)propyl] triphenylphosphonium bromide hydrobromide ( For Olopatadine ) [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide (Olopatadine) forOlopatadine 3-(4-bromo-2,3-diphenylphenyl)-N,N-dimethyl-1-propanamine hydrobromide 3-(Dimethylamino)Propyl]Triphenylphosphonium Bromide Hydrobromide,>98% [3-(Dimethylamino)propyl]triphenylphosphonium bromide hydrobromide ISO 9001：2015 REACH [3-(Dimethylamino)propyl]triphenyl-bromide phosphonium hydrobromide Olopatadine Impurity 8 HBr (3-dimethylaminopropyl)triphenylphospho-nium bromo hydrobrom... Hydrobromide (3-(dimethylamino)propyl)triphenylphosphonium bromide (3-DIMETHYLAMINOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE HYDROBROMIDE 3- (dimethylamino) propyl] triphenylphosphine bromide hydrobromide Olatadine Impurity 17(hydrobromide) Olopatadine Impurity 13 HBr [3-(dimethylamino)propyl](triphenyl)phosphonium bromide hydrobromide (1:1:1) 27710-82-3 7710-82-3 C23H27NPBrHBr CH32NCH2CH2CH2PC6H53BrHBr C23H28Br2NP C23H27BrPHBr C23H27NPBrBrH C-C Bond Formation Synthetic Reagents Wittig Reagents Olefination APIs Intermediate