Dihydrokawain
- CAS No.
- 587-63-3
- Chemical Name:
- Dihydrokawain
- Synonyms
- MARINDININ;DIHYDROKAVAIN;DIHYDROKAWAIN;dihydro-kawai;DIHYDROKAWAIN;DIHYDROKAVAIN(P);7,8-DIHYDROKAWAIN;7,8-Dihydrokavain;(S)-(+)-7,8-Dihydrokavain;Dihydrokavain (7,8-Dihydrokawain
- CBNumber:
- CB4314738
- Molecular Formula:
- C14H16O3
- Molecular Weight:
- 232.27
- MDL Number:
- MFCD01694032
- MOL File:
- 587-63-3.mol
- MSDS File:
- SDS
| Melting point | 58-60° |
|---|---|
| alpha | D24 +31° (methanol) |
| Boiling point | 314.44°C (rough estimate) |
| Density | 1.1649 (rough estimate) |
| refractive index | 1.5557 (estimate) |
| storage temp. | 2-8°C |
| solubility |
DMF:25.0(Max Conc. mg/mL);107.62(Max Conc. mM) DMSO:25.0(Max Conc. mg/mL);107.62(Max Conc. mM) Ethanol:5.0(Max Conc. mg/mL);21.52(Max Conc. mM) |
| optical activity | [α]/D 29±2°, c = 0.5 in methanol |
| BRN | 15362 |
| InChIKey | VOOYTQRREPYRIW-LBPRGKRZSA-N |
| LogP | 1.950 (est) |
| FDA UNII | NW8ZGW9XRZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Dihydrokawain price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 41866 | (S)-(+)-7,8-Dihydrokavain analytical standard | 587-63-3 | 5mg | $539 | 2022-05-15 | Buy |
| Usbiological | 361778 | Dihydrokawain | 587-63-3 | 10mg | $581 | 2021-12-16 | Buy |
| TRC | D450620 | (+)-(S)-Dihydrokavain | 587-63-3 | 1mg | $185 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD76571 | Dihydrokawain | 587-63-3 | 10mg | $250 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000214 | DIHYDROKAVAIN 95.00% | 587-63-3 | 5MG | $713.26 | 2021-12-16 | Buy |
Dihydrokawain Chemical Properties,Uses,Production
Chemical Properties
White-pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of kava-kava (Piper methysticum G. Forst).
Uses
(+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
Definition
ChEBI: Dihydrokavain is a member of 2-pyranones and an aromatic ether.
Application
Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.Used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
Preparation
Starting from 2,3-O-isopropylidene-D-glyceraldehyde (2) as chiral material, the naturally occurring (S)-(+)-dihydrokavain (1a) was synthesized by a procedure that involves a sonochemical Blaise reaction as the key step. The absolute configuration of (S)-(+)-dihydrokavain (1a) is demonstrated for the first time by total synthesis from a chiral source. Its opposite enantiomer, (R)-(–)-dihydrokavain (1b), was also synthesized after inversion of the chiral center in a Mitsunobu reaction.
A Total Synthesis of (+)- and (–)-Dihydrokavain with a Sonochemical Blaise Reaction as the Key Step
Dihydrokawain Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
View Lastest Price from Dihydrokawain manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Dihydrokavain
587-63-3
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2020-01-19 | DIHYDROKAVAIN
587-63-3
|
US $3.00 / KG | 1KG | 98% | 1kg,5kg,50kg | Career Henan Chemical Co |
-
- Dihydrokavain
587-63-3
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- DIHYDROKAVAIN
587-63-3
- US $3.00 / KG
- 98%
- Career Henan Chemical Co