ChemicalBook >> CAS DataBase List >>DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID
DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID
- CAS No.
- 76326-31-3
- Chemical Name:
- DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID
- Synonyms
- APV;AP-5;DL-AP5;DL-APV;C13734;(±)-2-AP5;5-phosphono-L-norvaline;Norvaline, 5-phosphono-;5-PHOSPHONO-DL-NORVALINE;2-amino-5-phosphopentanoicacid
- CBNumber:
- CB3448803
- Molecular Formula:
- C5H12NO5P
- Molecular Weight:
- 197.13
- MDL Number:
- MFCD00010515
- MOL File:
- 76326-31-3.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 238-245oC |
|---|---|
| Boiling point | 482.1±55.0 °C(Predicted) |
| Density | 1.529±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | NH4OH 1 M: 50 mg/mL, clear, colorless |
| pka | 2.46±0.10(Predicted) |
| form | solid |
| color | white |
| Water Solubility | Soluble to 10 mM in water and to 100 mM in 1eq. NaOH |
| BRN | 2446389 |
| CAS DataBase Reference | 76326-31-3(CAS DataBase Reference) |
| FDA UNII | 39PJ29YY8Z |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| NFPA 704 |
|
DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A5282 | DL-2-Amino-5-phosphonopentanoic acid solid | 76326-31-3 | 10mg | $110 | 2024-03-01 | Buy |
| Sigma-Aldrich | A5282 | DL-2-Amino-5-phosphonopentanoic acid solid | 76326-31-3 | 25mg | $298 | 2024-03-01 | Buy |
| Cayman Chemical | 14540 | DL-AP5 ≥95% | 76326-31-3 | 5mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 14540 | DL-AP5 ≥95% | 76326-31-3 | 10mg | $73 | 2024-03-01 | Buy |
| Sigma-Aldrich | A5282 | DL-2-Amino-5-phosphonopentanoic acid solid | 76326-31-3 | 50mg | $477 | 2024-03-01 | Buy |
DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Chemical Properties,Uses,Production
Uses
DL-2-Amino-5-phosphonopentanoic acid has been used:
- in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses
- used in growth medium for inhibition of electrical activity in the neuronal network
- used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product
- used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)
Definition
ChEBI: The 5-phosphono derivative of 2-aminopentanoic acid; acts as an N-methyl-D-aspartate receptor antagonist.
Biological Activity
Potent NMDA antagonist. See separate isomers (D-(-)-2-Amino-5-phosphonopentanoic acid and L-(+)-2-Amino-5-phosphonopentanoic acid ).
Biochem/physiol Actions
Anticonvulsant; potent and selective NMDA receptor antagonist.
storage
Room temperature
Synthesis of DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID from diethyl 2-acetamido-2-(3-(diethoxyphosphoryl)propyl)malonate
DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 64)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12755 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7433 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
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