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piperidine-4-propanol

piperidine-4-propanol structure

CAS No.: 7037-49-2

Chemical Name:: piperidine-4-propanol

Synonyms: Einecs 230-318-7;4-piperidinepropanol;4-piperidinopropanol;piperidine-4-propanol;4-Piperidine-1-propanol;3-Piperidin-4-propan-1-ol;3-(4-Piperidinyl)propanol;3-(4-Piperidyl)-1-propanol;4-(3-Hydroxypropy)piperidine;3-(4-Piperidinyl)-1-propanol

CBNumber:: CB3919129

Molecular Formula:: C8H17NO

Molecular Weight:: 143.23

MDL Number:: MFCD02178380

MOL File:: 7037-49-2.mol

MSDS File:: SDS

Last updated:2025-12-31 14:38:37

Product description	Number	Pack Size	Price
4-PIPERIDINEPROPANOL 97%	65242	1G	$42
4-PIPERIDINEPROPANOL 97%	65242	5G	$140
4-PIPERIDINEPROPANOL 97%	65242	25G	$475
4-(3-Hydroxypropyl)piperidine	H952655	50mg	$165
3-Piperidin-4-yl-propan-1-ol 95+%	020666	500mg	$27
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piperidine-4-propanol Properties

Melting point	65 °C
Boiling point	235℃
Density	0.929
Flash point	90℃
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	15.16±0.10(Predicted)
Appearance	White to light yellow Solid
InChI	InChI=1S/C8H17NO/c10-7-1-2-8-3-5-9-6-4-8/h8-10H,1-7H2
InChIKey	DBIMLJDSPUCGGY-UHFFFAOYSA-N
SMILES	N1CCC(CCCO)CC1
EPA Substance Registry System	4-Piperidinepropanol (7037-49-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
TSCA	TSCA listed
HazardClass	IRRITANT
HS Code	2933399990

piperidine-4-propanol price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AstaTech	65242	4-PIPERIDINEPROPANOL 97%	7037-49-2	1G	$42	2026-04-30	Buy
AstaTech	65242	4-PIPERIDINEPROPANOL 97%	7037-49-2	5G	$140	2026-04-30	Buy
AstaTech	65242	4-PIPERIDINEPROPANOL 97%	7037-49-2	25G	$475	2026-04-30	Buy
TRC	H952655	4-(3-Hydroxypropyl)piperidine	7037-49-2	50mg	$165	2021-12-16	Buy
Matrix Scientific	020666	3-Piperidin-4-yl-propan-1-ol 95+%	7037-49-2	500mg	$27	2021-12-16	Buy

Product number	Packaging	Price	Buy
65242	1G	$42	Buy
65242	5G	$140	Buy
65242	25G	$475	Buy
H952655	50mg	$165	Buy
020666	500mg	$27	Buy

piperidine-4-propanol Chemical Properties,Uses,Production

Uses

4-(3-Hydroxypropyl)piperidine is used in the synthesis of G-protein coupled receptor (GPR119) agonists based on a bicyclic amine scaffold. Also used in the synthesis and antimicrobial activities of novel quinoline derivatives.

Uses

piperidine-4-propanol is used in the synthesis of G-protein coupled receptor (GPR119) agonists based on a bicyclic amine scaffold. Also used in the synthesis and antimicrobial activities of no vel quinoline derivatives.

Synthesis

2629-72-3

7037-49-2

Platinum(IV) oxide (1.45 g, 6.4 mmol) was added to a mixed solution of 4-pyridinepropanol (10.0 g, 72.89 mmol) in methanol (110 mL) and 32% hydrochloric acid (18 mL) under argon protection. The reaction mixture was stirred vigorously under low pressure hydrogen (8 kPa) for 46 hours. Upon completion of the reaction, most of the catalyst was removed by filtration, followed by distillation under reduced pressure to remove the volatile solvent. The oily residue obtained was dissolved in 15% NaOH aqueous solution (80 mL) and extracted with dichloromethane (first 150 mL, then 3 x 100 mL). The organic phases were combined, washed with deionized water (20 mL) and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure and dried under vacuum to give 3-(4-piperidinyl)-1-propanol (10.3 g, 98% yield) as a white crystalline solid with a melting point of 58-60 °C. Thin layer chromatography (TLC) showed Rf = 0.2 (Expander: dichloromethane/methanol/28% ammonia = 50:10:1). Infrared spectroscopy (Nujol) showed characteristic absorption peaks located at 3290 cm1 and 1320 cm1. NMR hydrogen spectra (300 MHz, CDOD) δ (ppm): 1.08-1.23 (m, 2H), 1.27-1.36 (m, 2H), 1.36-1.49 (m, 1H), 1.53-1.63 (m, 2H). 1.74 (br d, 2H, J≈13.4 Hz), 2.59 (dt, 2H, J=12.4, 2.6 Hz), 3.04 (td, 2H, J=12.4, 2.9 Hz), 3.56 (t, 2H, J=6.6 Hz). NMR carbon spectrum (75 MHz, CDOD) δ (ppm): 31.5, 34.8, 35.2, 38.0, 47.9, 64.0. mass spectrum (ESI, MeOH) m/z (%): 287 (36) [2M+H] , 144 (100) [M+H] Molecular formula CHNO (molecular weight 143.2).

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 23, # 14, p. 3970 - 3990
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 16, p. 2537 - 2551
[3] Organic Letters, 2002, vol. 4, # 4, p. 549 - 552
[4] Tetrahedron, 1999, vol. 55, # 39, p. 11619 - 11639
[5] Journal of Polymer Science, 1959, vol. 40, p. 377,384

piperidine-4-propanol synthesis

Synthesis of piperidine-4-propanol from 4-Pyridinepropanol

piperidine-4-propanol Preparation Products And Raw materials

Raw materials

ETHYL 3-PIPERIDIN-4-YLPROPANOATE 2-Propyn-1-ol, 3-(4-pyridinyl)- (9CI) TERT-BUTYL 4-(3-HYDROXYPROPYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE 4-Pyridinepropanol 4-Iodopyridine

Hydrogen Hydrochloric acid Water Methanol Platinum dioxide

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Preparation Products

1-Boc-4-(3-broMopropyl)piperidine 1-Azabicyclo[3.2.2]nonane

piperidine-4-propanol Suppliers

Global( 132)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Unipharm pharmaceutical industry Co., Ltd	536-8266195 +8613953676784	lee@unipharm-sd.com	China	1202	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Richest Group Ltd	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Unipharm pharmaceutical industry Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from piperidine-4-propanol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	piperidine-4-propanol 7037-49-2	US $1.00 / KG	1KG	99%	1ton	Career Henan Chemical Co

piperidine-4-propanol
7037-49-2
US $1.00 / KG
99%
Career Henan Chemical Co

piperidine-4-propanol Spectrum

piperidine-4-propanol(7037-49-2)¹HNMR

7037-49-2(piperidine-4-propanol)Related Search:

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QUININE VALERATE TERT-BUTYL 4-(3-HYDROXYPROPYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE 1-Piperidine-1-propanol,piperidine-1-propanol α,α-Diphenyl-1-piperidine-1-propanol (±)-2-Methyl-1-piperidine-1-propanol benzoate,(2R)-2-Methyl-1-piperidine-1-propanol benzoate

α-(Bicyclo[2.2.1]hept-5-en-2-yl)-α-phenyl-1-piperidine-1-propanol α-Cyclopentyl-α-phenyl-1-piperidine-1-propanol Cevadine

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piperidine-4-propanol 4-piperidinepropanol 4-(3-Hydroxypropyl)piperidine 4-Piperidine-1-propanol Einecs 230-318-7 3-(4-Piperidyl)-1-propanol 3-(4-Piperidinyl)propanol 3-(4-Piperidinyl)-1-propanol 4-(3-Hydroxypropy)piperidine 3-Piperidin-4-propan-1-ol 4-Piperidinepropanol (6CI, 7CI, 8CI, 9CI, ACI) 4-piperidinopropanol 3-piperidin-4-yl-propan-1-ol, 97%min 4-Piperidinepropanol - [P13257] 7037-49-2 OLED materials,pharm chemical,electronic