L-(+)-Isoleucinol
- CAS No.
- 24629-25-2
- Chemical Name:
- L-(+)-Isoleucinol
- Synonyms
- L-ISOLEUCINOL;2-amino-3-methylpentan-1-ol;H-ILE-OL;L-Ile-ol;H-L-ILE-OL;H-ISOLEUCINOL;L(+)-ISOLEUCINOL;L-Isoleucinol>(+)-L-ISOLEUCINOL;(S)-(+)-ISOLEUCINOL
- CBNumber:
- CB4284679
- Molecular Formula:
- C6H15NO
- Molecular Weight:
- 117.19
- MDL Number:
- MFCD00004731
- MOL File:
- 24629-25-2.mol
- MSDS File:
- SDS
Melting point | 36-39 °C(lit.) |
---|---|
alpha | 4.5 º (c=1.6, EtOH) |
Boiling point | 97 °C14 mm Hg(lit.) |
Density | 0.9490 (rough estimate) |
refractive index |
n |
Flash point | 213 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
pka | 12.88±0.10(Predicted) |
form | Viscous Liquid |
color | White to light yellow |
optical activity | [α]20/D +4.0°, c = 1.6 in ethanol |
InChI | InChI=1S/C6H15NO/c1-3-5(2)6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t5-,6+/m0/s1 |
InChIKey | VTQHAQXFSHDMHT-NTSWFWBYSA-N |
SMILES | C(O)[C@@H](N)[C@@H](C)CC |
CAS DataBase Reference | 24629-25-2(CAS DataBase Reference) |
NIST Chemistry Reference | (S)-(+)-Isoleucinol(24629-25-2) |
UNSPSC Code | 12352209 |
NACRES | NA.22 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | C,Xi,Xn | |||||||||
Risk Statements | 34-22-40 | |||||||||
Safety Statements | 45-36/37/39-26-36-22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29221990 | |||||||||
NFPA 704 |
|
L-(+)-Isoleucinol price More Price(34)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 190527 | (S)-(+)-Isoleucinol 97% | 24629-25-2 | 1g | $22.48 | 2024-03-01 | Buy |
Sigma-Aldrich | 190527 | (S)-(+)-Isoleucinol 97% | 24629-25-2 | 5g | $145 | 2023-06-20 | Buy |
TCI Chemical | I0462 | L-Isoleucinol >97.0%(GC)(T) | 24629-25-2 | 1g | $51 | 2024-03-01 | Buy |
TCI Chemical | I0462 | L-Isoleucinol >97.0%(GC)(T) | 24629-25-2 | 5g | $117 | 2024-03-01 | Buy |
Alfa Aesar | H60556 | L-Isoleucinol, 97% | 24629-25-2 | 5g | $197 | 2021-12-16 | Buy |
L-(+)-Isoleucinol Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystalline solid or
Uses
peptide synthesis
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis

73-32-5

24629-25-2
The general procedure for the synthesis of L-isoleucinol from L-isoleucine is as follows: the synthesis of L-isoleucinol was carried out by reference to the literature method 61 with minor adjustments. Lithium aluminum hydride (7.2 g, 0.19 mol, 2.5 eq.) was suspended in anhydrous tetrahydrofuran (120 mL) under nitrogen protection with continuous stirring. Subsequently, L-isoleucine (10 g, 0.08 mol) was added in batches and the reaction suspension was heated to reflux for 20 hours. Upon completion of the reaction, it was cooled to room temperature, ethyl acetate was added slowly and the reaction mixture was carefully poured into concentrated sodium hydroxide solution. The organic layer was extracted with water and the organic phase was subsequently dried with sodium sulfate. Removal of the solvent under reduced pressure gave 4.5 g of L-isoleucinol as a yellow oil, which could be used in subsequent reactions without further purification. The product was characterized by 1H NMR (400 MHz, CDCl3) with the following chemical shifts: δ 0.75-0.90 (6H, m), 1.01-1.17 (1H, m), 1.22-1.36 (1H, m), 1.37-1.50 (1H, m), 2.48 (2H, br s), 2.50-2.65 (1H, m), 3.19 -3.29 (1H, m), 3.57 (1H, dd, J = 3.27,10.64Hz) ppm.
References
[1] Synthetic Communications, 1996, vol. 26, # 4, p. 703 - 706
[2] Russian Chemical Bulletin, 2008, vol. 57, # 9, p. 1981 - 1988
[3] Helvetica Chimica Acta, 2004, vol. 87, # 1, p. 90 - 105
[4] Journal of Organic Chemistry, 1993, vol. 58, # 13, p. 3568 - 3571
[5] Chemical Communications, 1997, # 12, p. 1087 - 1088
L-(+)-Isoleucinol Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23653 | 75 |
Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12648 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from L-(+)-Isoleucinol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-07-07 | L-(+)-Isoleucinol
24629-25-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
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2025-06-24 | L-(+)-Isoleucinol
24629-25-2
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-04-15 | L-isoleucinol
24629-25-2
|
US $10.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- L-(+)-Isoleucinol
24629-25-2
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- L-(+)-Isoleucinol
24629-25-2
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- L-isoleucinol
24629-25-2
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
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