ChemicalBook >> CAS DataBase List >>L-(+)-Isoleucinol

L-(+)-Isoleucinol

CAS No.
24629-25-2
Chemical Name:
L-(+)-Isoleucinol
Synonyms
L-ISOLEUCINOL;2-amino-3-methylpentan-1-ol;H-ILE-OL;L-Ile-ol;H-L-ILE-OL;H-ISOLEUCINOL;L(+)-ISOLEUCINOL;L-Isoleucinol>(+)-L-ISOLEUCINOL;(S)-(+)-ISOLEUCINOL
CBNumber:
CB4284679
Molecular Formula:
C6H15NO
Molecular Weight:
117.19
MDL Number:
MFCD00004731
MOL File:
24629-25-2.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47

L-(+)-Isoleucinol Properties

Melting point 36-39 °C(lit.)
alpha 4.5 º (c=1.6, EtOH)
Boiling point 97 °C14 mm Hg(lit.)
Density 0.9490 (rough estimate)
refractive index n20/D 1.4589(lit.)
Flash point 213 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 12.88±0.10(Predicted)
form Viscous Liquid
color White to light yellow
optical activity [α]20/D +4.0°, c = 1.6 in ethanol
InChI InChI=1S/C6H15NO/c1-3-5(2)6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t5-,6+/m0/s1
InChIKey VTQHAQXFSHDMHT-NTSWFWBYSA-N
SMILES C(O)[C@@H](N)[C@@H](C)CC
CAS DataBase Reference 24629-25-2(CAS DataBase Reference)
NIST Chemistry Reference (S)-(+)-Isoleucinol(24629-25-2)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  C,Xi,Xn
Risk Statements  34-22-40
Safety Statements  45-36/37/39-26-36-22-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29221990
NFPA 704
1
0 0

L-(+)-Isoleucinol price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 190527 (S)-(+)-Isoleucinol 97% 24629-25-2 1g $22.48 2024-03-01 Buy
Sigma-Aldrich 190527 (S)-(+)-Isoleucinol 97% 24629-25-2 5g $145 2023-06-20 Buy
TCI Chemical I0462 L-Isoleucinol >97.0%(GC)(T) 24629-25-2 1g $51 2024-03-01 Buy
TCI Chemical I0462 L-Isoleucinol >97.0%(GC)(T) 24629-25-2 5g $117 2024-03-01 Buy
Alfa Aesar H60556 L-Isoleucinol, 97% 24629-25-2 5g $197 2021-12-16 Buy
Product number Packaging Price Buy
190527 1g $22.48 Buy
190527 5g $145 Buy
I0462 1g $51 Buy
I0462 5g $117 Buy
H60556 5g $197 Buy

L-(+)-Isoleucinol Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystalline solid or

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

L-Isoleucine

73-32-5

L-(+)-Isoleucinol

24629-25-2

The general procedure for the synthesis of L-isoleucinol from L-isoleucine is as follows: the synthesis of L-isoleucinol was carried out by reference to the literature method 61 with minor adjustments. Lithium aluminum hydride (7.2 g, 0.19 mol, 2.5 eq.) was suspended in anhydrous tetrahydrofuran (120 mL) under nitrogen protection with continuous stirring. Subsequently, L-isoleucine (10 g, 0.08 mol) was added in batches and the reaction suspension was heated to reflux for 20 hours. Upon completion of the reaction, it was cooled to room temperature, ethyl acetate was added slowly and the reaction mixture was carefully poured into concentrated sodium hydroxide solution. The organic layer was extracted with water and the organic phase was subsequently dried with sodium sulfate. Removal of the solvent under reduced pressure gave 4.5 g of L-isoleucinol as a yellow oil, which could be used in subsequent reactions without further purification. The product was characterized by 1H NMR (400 MHz, CDCl3) with the following chemical shifts: δ 0.75-0.90 (6H, m), 1.01-1.17 (1H, m), 1.22-1.36 (1H, m), 1.37-1.50 (1H, m), 2.48 (2H, br s), 2.50-2.65 (1H, m), 3.19 -3.29 (1H, m), 3.57 (1H, dd, J = 3.27,10.64Hz) ppm.

References

[1] Synthetic Communications, 1996, vol. 26, # 4, p. 703 - 706
[2] Russian Chemical Bulletin, 2008, vol. 57, # 9, p. 1981 - 1988
[3] Helvetica Chimica Acta, 2004, vol. 87, # 1, p. 90 - 105
[4] Journal of Organic Chemistry, 1993, vol. 58, # 13, p. 3568 - 3571
[5] Chemical Communications, 1997, # 12, p. 1087 - 1088

L-(+)-Isoleucinol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 284)Suppliers
Supplier Tel Email Country ProdList Advantage
TCI AMERICA
800-4238616 sales@tciamerica.com Americas 23653 75
Hebei Chuanghai Biotechnology Co., Ltd
+8617732866630 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd
+86-13288715578 sales@hbmojin.com China 12648 58
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+8613343047651 admin@zlchemi.com China 3692 58
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BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10821 58

View Lastest Price from L-(+)-Isoleucinol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-(+)-Isoleucinol pictures 2025-07-07 L-(+)-Isoleucinol
24629-25-2
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
L-(+)-Isoleucinol pictures 2025-06-24 L-(+)-Isoleucinol
24629-25-2
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
L-isoleucinol pictures 2025-04-15 L-isoleucinol
24629-25-2
US $10.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
  • L-(+)-Isoleucinol pictures
  • L-(+)-Isoleucinol
    24629-25-2
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • L-isoleucinol pictures
  • L-isoleucinol
    24629-25-2
  • US $10.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
(2S,3S)-2-AMINO-3-METHYL-PENTAN-1-OL (2S,3S)-2-AMINO-3-METHYL-1-PENTANOL 2-AMINO-3-METHYL-1-PENTANOL (S)-(+)-Isoleucinol,(2S,3S)-2-Amino-3-methyl-1-pentanol, L-Isoleucinol (S)-(+)-Isoleucinol 97% (S)-(-)-2-aMino-3-Methylpentan-1-ol (S)-(+)-Isoleucinol, 95+% L-Isoleucinol,99%e.e. l-2-Amino-3-methyl-1-pentanol (+)-L-ISOLEUCINOL L(+)-ISOLEUCINOL H-ILE-OL H-L-ILE-OL H-ISOLEUCINOL (S)-(+)-2-AMINO-3-METHYL-1-PENTANOL (S)-(+)-ISOLEUCINOL (S,S)-2-AMINO-3-METHYL-1-PENTANOL 1-Pentanol, 2-amino-3-methyl-, [S-(R*,R*)]- L-Ile-ol (S)-(+)-ISOLEUCINOL / L-(+)-2-AMINO-3-METHYL-1-PENTANOL 1-PENTANOL, 2-AMINO-3-METHYL-, (2S,3S)- (2S,3S)-2-Amino-3-methyl-1-pentanol, L-Isoleucinol (2S,3S)-3-Methyl-2-amino-1-pentanol L(+)-Isoleucinol,97% L-Isoleucinol,(2S,3S)-2-Amino-3-methyl-1-pentanol [(2S,3S)-1-hydroxy-3-methylpentan-2-yl]ammonium L-Isoleucinol> L-(+)-Isoleucinol USP/EP/BP L-ISOLEUCINOL 2-amino-3-methylpentan-1-ol (S)-(+)-Isoleucinol 24629-25-2 24629-25-1 C2H5CHCH3CHNH2CH2OH Chiral Building Blocks Amino Alcohols (Chiral) Peptide Synthesis Specialty Synthesis Amino Alcohols Amino Acid Derivatives Pharmaceutical Intermediates Amines blocks Amino Alcohols Isoleucine [Ile, I] Amino Alcohols (Chiral) Chiral Building Blocks Synthetic Organic Chemistry Chiral Compound Amino alcohols